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Database: UniProt
Entry: A0A136HWF1_9ALTE
LinkDB: A0A136HWF1_9ALTE
Original site: A0A136HWF1_9ALTE 
ID   A0A136HWF1_9ALTE        Unreviewed;       539 AA.
AC   A0A136HWF1;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   25-OCT-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AXW14_14080 {ECO:0000313|EMBL:KXJ59966.1};
OS   Alteromonas sp. Nap_26.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Alteromonas.
OX   NCBI_TaxID=1795869 {ECO:0000313|EMBL:KXJ59966.1, ECO:0000313|Proteomes:UP000070342};
RN   [1] {ECO:0000313|EMBL:KXJ59966.1, ECO:0000313|Proteomes:UP000070342}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nap_26 {ECO:0000313|EMBL:KXJ59966.1};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KXJ59966.1}.
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DR   EMBL; LSMP01000174; KXJ59966.1; -; Genomic_DNA.
DR   Proteomes; UP000070342; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000070342};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070342}.
FT   DOMAIN      236    438       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      447    516       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     244    251       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   539 AA;  60734 MW;  FB654E3CF8799BC9 CRC64;
     MSLWNQCLER LRQELPTQQF SMWIRPLVCE EQDGYVALYA PNRFVLDWVR DKYLNNITAL
     LREFAGADAP QLHLEVMSRQ SLNRSAPAAT QQSSQSNVNT PSRYNAGNTS TPSAAPHNAS
     QPSANNVAMG RDGQSRMPTQ ASPNYSQNNG SFGYQQNDHN MESARSDHYD RATNNGNSYG
     QPPRSHTPPK VIPIPEAMKH KSNINPTYQF DNFVEGKSNQ LARAAATQVA NNPGGSYNPL
     FIYGGTGLGK THLLHAVGNG IVANNGDAKI VYMHSERFVQ DMVKALQNNA IEDFKRFYRS
     VDALLIDDIQ FFANKERSQE EFFHTFNALL EGNQQIILTS DRYPKEIDGV EDRLKSRFGW
     GLTIAIEPPE LETRVAILMR KAAENRIHLP NEVAFFIAKR LRSNVRELEG ALNRVIANAN
     FTGRPITIDF VREALRDLLA LQEKLVTVDN IQKTVADYYK IKVADILSKR RSRSVARPRQ
     VAMALAKELT NHSLPELGNA FGGRDHTTVL HACRKIEQLR EESHDIKEDY KNLIRTLSS
//
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