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Database: UniProt
Entry: A0A136I1K4_9ALTE
LinkDB: A0A136I1K4_9ALTE
Original site: A0A136I1K4_9ALTE 
ID   A0A136I1K4_9ALTE        Unreviewed;       551 AA.
AC   A0A136I1K4;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   30-AUG-2017, entry version 11.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AXW14_17985 {ECO:0000313|EMBL:KXJ61762.1};
OS   Alteromonas sp. Nap_26.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Alteromonas.
OX   NCBI_TaxID=1795869 {ECO:0000313|EMBL:KXJ61762.1, ECO:0000313|Proteomes:UP000070342};
RN   [1] {ECO:0000313|EMBL:KXJ61762.1, ECO:0000313|Proteomes:UP000070342}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Nap_26 {ECO:0000313|EMBL:KXJ61762.1};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KXJ61762.1}.
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DR   EMBL; LSMP01000050; KXJ61762.1; -; Genomic_DNA.
DR   Proteomes; UP000070342; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000070342};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070342}.
FT   DOMAIN      248    450       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      459    528       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     256    263       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   551 AA;  61596 MW;  4B51DAE8C2312983 CRC64;
     MSLWNQCLER LRQELPTQQF SMWIRPLVCE EQQGVVALYA PNRFVLDWVR DKYLNNITAL
     LKEFAGSDAP QLRLEVMNRH SVSRSQPVST SGSSPAPNTP NNQPSKPSAP AGGQGYQNYN
     TSNQPVHSGS NGQHTSSYSP MSNSGMPSSA SQAGDQGQNN AFSKSPSYTQ GMDLNDRGAQ
     NHDRNGYNAY ADQAPRSSTP PKVIPIPEAM KHKSNINPTY QFDNFVEGKS NQLARAAATQ
     VANNPGGSYN PLFIYGGTGL GKTHLLHAVG NGIVANNGDA KIVYMHSERF VQDMVKALQN
     NAIEDFKRFY RSVDALLIDD IQFFANKERS QEEFFHTFNA LLEGNQQIIL TSDRYPKEID
     GVEDRLKSRF GWGLTIAIEP PELETRVAIL MRKAAENRIH LPNEVAFFIA KRLRSNVREL
     EGALNRVIAN ANFTGRPITI DFVREALRDL LALQEKLVTV DNIQKTVADY YKIKVADILS
     KRRSRSVARP RQVAMALAKE LTNHSLPELG NAFGGRDHTT VLHACRKIEQ LREESHDIKE
     DYKNLIRTLS S
//
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