ID   A0A136JDC6_9PEZI        Unreviewed;      1051 AA.
AC   A0A136JDC6;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Lactase {ECO:0000256|ARBA:ARBA00032230};
GN   ORFNames=Micbo1qcDRAFT_143399 {ECO:0000313|EMBL:KXJ95171.1};
OS   Microdochium bolleyi.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Microdochiaceae; Microdochium.
OX   NCBI_TaxID=196109 {ECO:0000313|EMBL:KXJ95171.1, ECO:0000313|Proteomes:UP000070501};
RN   [1] {ECO:0000313|Proteomes:UP000070501}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J235TASD1 {ECO:0000313|Proteomes:UP000070501};
RG   DOE Joint Genome Institute;
RA   David A.S., May G., Haridas S., Lim J., Wang M., Labutti K., Lipzen A.,
RA   Barry K., Grigoriev I.V.;
RT   "Draft genome sequence of Microdochium bolleyi, a fungal endophyte of
RT   beachgrass.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; KQ964246; KXJ95171.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A136JDC6; -.
DR   STRING; 196109.A0A136JDC6; -.
DR   InParanoid; A0A136JDC6; -.
DR   OrthoDB; 276651at2759; -.
DR   Proteomes; UP000070501; Unassembled WGS sequence.
DR   GO; GO:0009341; C:beta-galactosidase complex; IEA:InterPro.
DR   GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 2.70.98.10; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR004199; B-gal_small/dom_5.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   InterPro; IPR006101; Glyco_hydro_2.
DR   InterPro; IPR023232; Glyco_hydro_2_AS.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR032312; LacZ_4.
DR   PANTHER; PTHR46323; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR46323:SF1; LACTASE; 1.
DR   Pfam; PF02929; Bgal_small_N; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   Pfam; PF16353; LacZ_4; 1.
DR   PRINTS; PR00132; GLHYDRLASE2.
DR   SMART; SM01038; Bgal_small_N; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 2.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070501}.
FT   DOMAIN          754..1046
FT                   /note="Beta galactosidase small chain/"
FT                   /evidence="ECO:0000259|SMART:SM01038"
SQ   SEQUENCE   1051 AA;  117375 MW;  E5A455A620FDF92D CRC64;
     MAQQASGKPD YANLEVLQRN RLPARAYWIP STLLLLNGVW DFHYALSPLE APVLTEQSAA
     VKPDNSWTTI NVPGHWQLQG HGRPHYTNTV YPFPSCPPHI PDENPTGTYR RVFAVPADWE
     ASSQLRLRFD GVDSAYHVWL NGTFVGYSQG SRNPAEFDIS SVVKRGGDVN ELVVQVYQWC
     EATYIEDQDQ WWMSGIFRDV NLLAFPEARV EDFFVKTDLD KEYKDATVLV DLTLHVPESA
     ANKDLKLSLR DGANEVTSST HQVSSKDGTL QVQFDVKNPN KWTAETPSLY QLEITLGSQI
     ITQSVGFRKV ELKDGLITVN GTPLLLRGAN RHEHHPRLGR AVPYEFMKQD LLLMKQHNIN
     ALRCSHYPSQ PRLYDLASEL GLWVMDEADL ECHGFYDVVM QAANMPREDD YEGSKDLFFP
     RAAAFTSDNP AWREAYVDRM RQLVQRDKNH PCIFSWSLGN EAFFGQNHVA MADYARAADP
     SRVIHYEGDI KAQVTDMFSY MYSPPAKLVQ LTEEVGVARD TGKFDKPVIL CEYAHAMGNG
     PGALDDYQEL FRKYPRLQGG FIWEWANHGL WREDGGYYAY GGDFGDKPND GTFVMDGLCN
     SEHKPTPGLT ELKKVFQPVK FDFDRDSGKV FVTNEYAFTG LEHLVGTYTV EALDEKSTQL
     EAGELSIPTV APGARVELEI PADIRQYEKH EQETFLTIKF SLAKDTAWAQ AGHEIAWYQH
     KISAHDYKSS TLSSAAESPI PAKLEIRDSR SKLTVSGPDC SFTFDRVRGY LTSWTRGRQD
     DTTTTTTLLE ADPATHAAIF PNFWRAPTDN DKGAALAGWL EQRVNTITST LRSFEVKDNQ
     PGGAVVVETH TWLAPPVLGW GYDAHTTYTV SPGGSLSVKV SLKTAGEAGP KDVPRVGLSV
     RLPKRLDQAS WFGLGPGESY PDKRTAQRTG IWESSVDGLE VPYDVPQENG NRMETRWVRL
     AAGESEGGVG FKASRRDQST FSWTGGRLSV ETIEGAKHPC DMVREEATLL NLSAKVAGVG
     SAACGPGVRE DLLVKFEDME FEFVLEPIAS A
//