ID   A0A136JL69_9BACT        Unreviewed;       351 AA.
AC   A0A136JL69;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   RecName: Full=RNA polymerase sigma factor {ECO:0000256|RuleBase:RU362124};
GN   Name=sigA {ECO:0000313|EMBL:KXJ97883.1};
GN   ORFNames=UZ19_OD1000947 {ECO:0000313|EMBL:KXJ97883.1};
OS   Parcubacteria bacterium OLB19.
OC   Bacteria; Candidatus Parcubacteria.
OX   NCBI_TaxID=1617425 {ECO:0000313|EMBL:KXJ97883.1, ECO:0000313|Proteomes:UP000070365};
RN   [1] {ECO:0000313|EMBL:KXJ97883.1, ECO:0000313|Proteomes:UP000070365}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OLB19 {ECO:0000313|EMBL:KXJ97883.1};
RA   Speth D.R., In T Zandt M., Guerrero Cruz S., Jetten M.S., Dutilh B.E.;
RT   "Improved understanding of the partial-nitritation anammox process through
RT   23 genomes representing the majority of the microbial community.";
RL   Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. {ECO:0000256|RuleBase:RU362124}.
CC   -!- SIMILARITY: Belongs to the sigma-70 factor family.
CC       {ECO:0000256|RuleBase:RU362124}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXJ97883.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JZEL01000029; KXJ97883.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A136JL69; -.
DR   STRING; 1617425.UZ19_OD1000947; -.
DR   PATRIC; fig|1617425.3.peg.965; -.
DR   Proteomes; UP000070365; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   CDD; cd06171; Sigma70_r4; 1.
DR   Gene3D; 1.10.601.10; RNA Polymerase Primary Sigma Factor; 2.
DR   Gene3D; 1.10.220.120; Sigma-70 factor, region 1.1; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR014284; RNA_pol_sigma-70_dom.
DR   InterPro; IPR000943; RNA_pol_sigma70.
DR   InterPro; IPR009042; RNA_pol_sigma70_r1_2.
DR   InterPro; IPR007627; RNA_pol_sigma70_r2.
DR   InterPro; IPR007624; RNA_pol_sigma70_r3.
DR   InterPro; IPR007630; RNA_pol_sigma70_r4.
DR   InterPro; IPR007127; RNA_pol_sigma_70_r1_1.
DR   InterPro; IPR042189; RNA_pol_sigma_70_r1_1_sf.
DR   InterPro; IPR013325; RNA_pol_sigma_r2.
DR   InterPro; IPR013324; RNA_pol_sigma_r3/r4-like.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   NCBIfam; TIGR02937; sigma70-ECF; 1.
DR   PANTHER; PTHR30603; RNA POLYMERASE SIGMA FACTOR RPO; 1.
DR   PANTHER; PTHR30603:SF47; RNA POLYMERASE SIGMA FACTOR SIGF, CHLOROPLASTIC; 1.
DR   Pfam; PF03979; Sigma70_r1_1; 1.
DR   Pfam; PF00140; Sigma70_r1_2; 1.
DR   Pfam; PF04542; Sigma70_r2; 1.
DR   Pfam; PF04539; Sigma70_r3; 1.
DR   Pfam; PF04545; Sigma70_r4; 1.
DR   PRINTS; PR00046; SIGMA70FCT.
DR   SUPFAM; SSF88946; Sigma2 domain of RNA polymerase sigma factors; 1.
DR   SUPFAM; SSF88659; Sigma3 and sigma4 domains of RNA polymerase sigma factors; 2.
DR   PROSITE; PS00715; SIGMA70_1; 1.
DR   PROSITE; PS00716; SIGMA70_2; 1.
PE   3: Inferred from homology;
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362124};
KW   Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW   ECO:0000256|RuleBase:RU362124};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|RuleBase:RU362124};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|RuleBase:RU362124}.
FT   DOMAIN          143..156
FT                   /note="RNA polymerase sigma-70"
FT                   /evidence="ECO:0000259|PROSITE:PS00715"
FT   DOMAIN          313..339
FT                   /note="RNA polymerase sigma-70"
FT                   /evidence="ECO:0000259|PROSITE:PS00716"
SQ   SEQUENCE   351 AA;  40530 MW;  BB2AB54939092CC3 CRC64;
     MKAAELMRLG RERGYITYDE LLRSFPEIEK DIEFLDVLYE RFSIAGIDVL QSGGMLGEDP
     SIDIIAQKNA FKRSDSSYDS IQMYLREIGQ YPLLNAFEER MLAKRIVEGD EEARNLLARA
     NLRLVVSIAK KYVGRSPDLT LLDLIQEGNL GLFKAVDKFD FTKGFKFSTY ATWWIRQAIT
     RALADQSRTI RIPVHMVETM AKYKQVSRRL SQDLGREPMP EEIATEMGVE VEKIYQIEKI
     SQDTISLELP VGDEDDRSRL SDFISDDKIV SPDQEVAHSI LTDQITEILD TLSEKERKIL
     EMRHGLLDGT YHTLEEVGKE FGVTRERIRQ IEAKALEKIR QHEKARRLKS Y
//