ID A0A136KRZ9_9CHLR Unreviewed; 744 AA.
AC A0A136KRZ9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:KXK12171.1};
GN Name=mrdA {ECO:0000313|EMBL:KXK12171.1};
GN ORFNames=UZ14_CFX002002525 {ECO:0000313|EMBL:KXK12171.1};
OS Chloroflexi bacterium OLB14.
OC Bacteria; Chloroflexota; Tepidiformia.
OX NCBI_TaxID=1617415 {ECO:0000313|EMBL:KXK12171.1, ECO:0000313|Proteomes:UP000070321};
RN [1] {ECO:0000313|EMBL:KXK12171.1, ECO:0000313|Proteomes:UP000070321}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OLB14 {ECO:0000313|EMBL:KXK12171.1};
RA Speth D.R., In T Zandt M., Guerrero Cruz S., Jetten M.S., Dutilh B.E.;
RT "Genome based microbial ecology of anammox granules in a full-scale
RT wastewater treatment system.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXK12171.1}.
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DR EMBL; LMZR01000053; KXK12171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136KRZ9; -.
DR STRING; 1617415.UZ14_CFX002002525; -.
DR PATRIC; fig|1617415.3.peg.2548; -.
DR Proteomes; UP000070321; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 59..274
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 321..727
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 744 AA; 82051 MW; B2C4AA125B029546 CRC64;
MSSNSNNPVR FETWRIATIY GVIIIAFSVL FTRLINLQIF QTADYNARAK DNYTQEVSVP
APRGIIYDRN GYVLARNVAT YNIIITPANL PEDNSDIQQI YRDLSKLIDV PAGSFIAEDS
ITEETLVEVP GGYLTETALE EAKLFTACVP GLSIAQMVAL QDTLAPYSPV RVSCNVSEEI
ARKVEEKAMD WQGVEVEIEA VRDYPTGSLT AHLIGFLGPI PASLEEEYVA QGYVLNRDKI
GYSGVEASLQ DILTGRNGLR VVQVDVAGQE IRNLEPPIAP SPGNNVYLSI DTRLQAAAQA
TFMEEMRFWN TYFGNTRISS GVIIAMNPKT GEILAMVSYP DYENNRFSRI IPAYYYEQLS
QDPRKPLLNN AISAEYPPGS TFKLSTATGA INEGVVDLNQ IIDTPGQLLL CERFNPNDIC
SDANTRPFVD HIFDQNPGGF GSLRFLQCIA YSSNVCFYKL GGGYEDEIPQ GLGIERLRQY
ARALGYDETS GIQLLGEQDG LIPEPDWKRI NTGENWSTGD TYIASVGQGY VLATPLQVLM
SGSVIANYGK LMQPTVVHQV TDGDGNIIPY WFNPEEFTVS QFETQNSYQI SPFTANMKWD
VTVDPLIQEY ICFDTYCDLT DELKTIKPES IQAVREGTRL AVTDPAFGTL HDLFSDFPIA
VAGKTGTAEY CDDVARAANR CAFGAWPTHS WTLAYAPYDD PEIIVVAFAY NGGEGASVAG
PMVARMIKSY FEIKATDLAN GANP
//
