ID A0A136PKF4_9ACTN Unreviewed; 341 AA.
AC A0A136PKF4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KXK58874.1};
GN ORFNames=AWW66_27340 {ECO:0000313|EMBL:KXK58874.1};
OS Micromonospora rosaria.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47874 {ECO:0000313|EMBL:KXK58874.1, ECO:0000313|Proteomes:UP000070620};
RN [1] {ECO:0000313|EMBL:KXK58874.1, ECO:0000313|Proteomes:UP000070620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 803 {ECO:0000313|EMBL:KXK58874.1,
RC ECO:0000313|Proteomes:UP000070620};
RA Yang H., He X., Zhu D.;
RT "Whole genome sequence and analysis of Micromonospora rosaria DSM 803,
RT which can produce antibacterial substance rosamicin.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXK58874.1}.
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DR EMBL; LRQV01000148; KXK58874.1; -; Genomic_DNA.
DR RefSeq; WP_067372115.1; NZ_LRQV01000148.1.
DR AlphaFoldDB; A0A136PKF4; -.
DR OrthoDB; 9785139at2; -.
DR Proteomes; UP000070620; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000070620};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..64
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 341 AA; 36175 MW; 6C88D6AFA760BB57 CRC64;
MGQQPVVRAA VMSDVARLAG VSHQTVSRVL NNHPSVRPET RERVLRAVHQ LNYRPNALAR
GLAGRRSRVI GVVSFDTILY GPAATLLGIE RAARAAGYGI NIVTLERLDR AGMKSAIDAL
TEQSVAGVVI IAPMMTAALA VHGLPTGVPA VVVESGGGTG ELPSVSVDQV AGARLAVEHL
LALGHETVWH VAGPRDWLEA RDRVDGWRLA LEQAGRRVPA VVPGDWSPRA GYEIGQSLVD
RPDVTAVFCA NDHQALGLLR ALHQRGVRVP EDVSVVGFDD IPEAEYLSPP LTTVRQDFDE
VGRRCVAALL ALLGAAGSTG PEPAQVEPVL VVRDSSGPRR S
//
