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Database: UniProt
Entry: A0A136Q490_9FIRM
LinkDB: A0A136Q490_9FIRM
Original site: A0A136Q490_9FIRM 
ID   A0A136Q490_9FIRM        Unreviewed;       466 AA.
AC   A0A136Q490;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   25-OCT-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=HMPREF3293_01681 {ECO:0000313|EMBL:KXK65467.1};
OS   Christensenella minuta.
OC   Bacteria; Firmicutes; Clostridia; Clostridiales; Christensenellaceae;
OC   Christensenella.
OX   NCBI_TaxID=626937 {ECO:0000313|EMBL:KXK65467.1, ECO:0000313|Proteomes:UP000070366};
RN   [1] {ECO:0000313|EMBL:KXK65467.1, ECO:0000313|Proteomes:UP000070366}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22607 {ECO:0000313|EMBL:KXK65467.1,
RC   ECO:0000313|Proteomes:UP000070366};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KXK65467.1}.
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DR   EMBL; LSZW01000061; KXK65467.1; -; Genomic_DNA.
DR   RefSeq; WP_066519761.1; NZ_MAIR01000002.1.
DR   EnsemblBacteria; KXK65467; KXK65467; HMPREF3293_01681.
DR   PATRIC; fig|626937.4.peg.1662; -.
DR   Proteomes; UP000070366; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000070366};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070366}.
FT   DOMAIN      145    280       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      375    443       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     153    160       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   466 AA;  53787 MW;  DB1853DD8AD75BF6 CRC64;
     MSVFNVLWEK TLNYLEEDLP MFQFNVWIKE LKPVHEEDGT YYFEVSSPMH KSLMEEKYAE
     KIRLTMQLAY EELYGVPGAD IRPEFITPQD SSKLNINEKK AEPQPAREQK TNLNPNYTFD
     TFVVGEANKF ANAAALAVAQ APGRAYNPLF LYGGVGLGKT HLMHAVGNHI LQDNPGAEIV
     YVTSETFMNE LIRMIQLTNN RANIDLREQF RRKYRNIDVL LIDDIQFIAG KDVAQDEFFH
     TFNALRDMNK QIVISSDRPP KEMEKLEERM RCRFEWGLIA DIKMPDYETR VAILLKKVQA
     LRSVNPSALP IRDDALHYIA QQKNSNIRTL EGALQKVIMY AELHKESLPS GEIDASVAQK
     ALEDFFASPS VRAITPKGVV DVVCEYFDIR EEDIRGQKRN REYVFPRQIS MFVLRDLTDS
     SYSKIAEFFD RDHSTIMHAE EKIKKQMKDD PELKKVVEDI EAKIKG
//
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