ID   A0A136WB95_9FIRM        Unreviewed;       485 AA.
AC   A0A136WB95;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Cytosol non-specific dipeptidase {ECO:0000313|EMBL:KXL51797.1};
DE            EC=3.4.13.18 {ECO:0000313|EMBL:KXL51797.1};
GN   Name=pepD_2 {ECO:0000313|EMBL:KXL51797.1};
GN   ORFNames=CLNEO_28640 {ECO:0000313|EMBL:KXL51797.1};
OS   Anaerotignum neopropionicum.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Anaerotignum.
OX   NCBI_TaxID=36847 {ECO:0000313|EMBL:KXL51797.1, ECO:0000313|Proteomes:UP000070539};
RN   [1] {ECO:0000313|EMBL:KXL51797.1, ECO:0000313|Proteomes:UP000070539}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM-3847 {ECO:0000313|EMBL:KXL51797.1,
RC   ECO:0000313|Proteomes:UP000070539};
RA   Poehlein A., Beck M.H., Bengelsdorf F.R., Daniel R., Duerre P.;
RT   "Genome sequence of Clostridium neopropionicum X4, DSM-3847.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXL51797.1}.
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DR   EMBL; LRVM01000015; KXL51797.1; -; Genomic_DNA.
DR   RefSeq; WP_066090789.1; NZ_LRVM01000015.1.
DR   AlphaFoldDB; A0A136WB95; -.
DR   STRING; 36847.CLNEO_28640; -.
DR   PATRIC; fig|36847.3.peg.3351; -.
DR   OrthoDB; 9773892at2; -.
DR   Proteomes; UP000070539; Unassembled WGS sequence.
DR   GO; GO:0103046; F:alanylglutamate dipeptidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd03890; M20_pepD; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 2.
DR   InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR   InterPro; IPR002933; Peptidase_M20.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   InterPro; IPR001160; Peptidase_M20C.
DR   NCBIfam; TIGR01893; aa-his-dipept; 1.
DR   PANTHER; PTHR43501; CYTOSOL NON-SPECIFIC DIPEPTIDASE; 1.
DR   PANTHER; PTHR43501:SF1; CYTOSOL NON-SPECIFIC DIPEPTIDASE; 1.
DR   Pfam; PF07687; M20_dimer; 1.
DR   Pfam; PF01546; Peptidase_M20; 1.
DR   PIRSF; PIRSF016599; Xaa-His_dipept; 1.
DR   PRINTS; PR00934; XHISDIPTASE.
DR   SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Dipeptidase {ECO:0000313|EMBL:KXL51797.1};
KW   Hydrolase {ECO:0000313|EMBL:KXL51797.1};
KW   Protease {ECO:0000313|EMBL:KXL51797.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070539}.
FT   DOMAIN          207..292
FT                   /note="Peptidase M20 dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF07687"
SQ   SEQUENCE   485 AA;  54218 MW;  D5D2357AF9F35816 CRC64;
     MGKLDGLGGD KVFYFFEEIC NIPHGSENER ALSDYIVGFA KKRGLYCRQD EHYNVLIKKA
     GSKGYENAAP IILQGHIDMV CEKNAETELN FLTDPIEIYV DGDFIHAKGT TLGADDGIAV
     AYMLALLEDD ALAHPPIEAI FTVEEETGMG GARAFETFDL EGKRFLNMDT EEEGVLLSGC
     AGGRRIRVYL PAERNDSPVG RKGYMISIRG LKGGHSGADI HLQRANANPL MGRILYMLKE
     AVDFSLAGVD GGNMDNAICR EAEATVLFAD KDEETVRELL KKIEKGFQEE YNSRETSITI
     TMETLQEEVF KVLTEDTKNK LIYILLLLPY GVQTMSMEME GLVESSNNIG IVRTTSEHIY
     FDNAVRSSVE SRKELICQKI YGIANLCGAS VENLNDYPGW RFNPDSQLLE LFAKTYREFY
     GKEAEISAIH AGLECGLFLE KIPNLDMVSI GPELHDVHTP DERLSISSTI RVWEFLKEVL
     KKMDH
//