ID A0A136WDJ6_9FIRM Unreviewed; 470 AA.
AC A0A136WDJ6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=HTH-type transcriptional regulatory protein GabR {ECO:0000313|EMBL:KXL52592.1};
GN Name=gabR_2 {ECO:0000313|EMBL:KXL52592.1};
GN ORFNames=CLNEO_20010 {ECO:0000313|EMBL:KXL52592.1};
OS Anaerotignum neopropionicum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerotignum.
OX NCBI_TaxID=36847 {ECO:0000313|EMBL:KXL52592.1, ECO:0000313|Proteomes:UP000070539};
RN [1] {ECO:0000313|EMBL:KXL52592.1, ECO:0000313|Proteomes:UP000070539}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM-3847 {ECO:0000313|EMBL:KXL52592.1,
RC ECO:0000313|Proteomes:UP000070539};
RA Poehlein A., Beck M.H., Bengelsdorf F.R., Daniel R., Duerre P.;
RT "Genome sequence of Clostridium neopropionicum X4, DSM-3847.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: In the C-terminal section; belongs to the class-I
CC pyridoxal-phosphate-dependent aminotransferase family.
CC {ECO:0000256|ARBA:ARBA00005384}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXL52592.1}.
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DR EMBL; LRVM01000006; KXL52592.1; -; Genomic_DNA.
DR RefSeq; WP_066088287.1; NZ_LRVM01000006.1.
DR AlphaFoldDB; A0A136WDJ6; -.
DR STRING; 36847.CLNEO_20010; -.
DR PATRIC; fig|36847.3.peg.2352; -.
DR OrthoDB; 9799482at2; -.
DR Proteomes; UP000070539; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR CDD; cd00609; AAT_like; 1.
DR CDD; cd07377; WHTH_GntR; 1.
DR Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR004839; Aminotransferase_I/II.
DR InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR InterPro; IPR000524; Tscrpt_reg_HTH_GntR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR46577; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR PANTHER; PTHR46577:SF1; HTH-TYPE TRANSCRIPTIONAL REGULATORY PROTEIN GABR; 1.
DR Pfam; PF00155; Aminotran_1_2; 1.
DR Pfam; PF00392; GntR; 1.
DR SMART; SM00345; HTH_GNTR; 1.
DR SUPFAM; SSF53383; PLP-dependent transferases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50949; HTH_GNTR; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW Reference proteome {ECO:0000313|Proteomes:UP000070539};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 22..90
FT /note="HTH gntR-type"
FT /evidence="ECO:0000259|PROSITE:PS50949"
SQ SEQUENCE 470 AA; 52641 MW; 98D42547E337ECE7 CRC64;
MPVNSFTDYP MSWKPEKSKL CQPLYLSLVK LLEQDIKNGT LAPHTKLPPQ RELADYLDIN
LSTVTKAFKQ CQLNGFLYAV VGRGTFVAPN AGVSISIQDT KISPSLIEMG IIKPIDAFNH
YTEDALKKVL RKKSADSLLD YSAPFGSPFQ KSAAEKWLSK FGLHPHPEDI FFTTGGQNAF
AVVLITLFHH GDKIATDRFT YSNFIELANM LNIKLVPIQA DERGMLPEDL EMQCRLQGLQ
GVYLVPTYSN PTGTIMDTAR KEALAKIIRT HHLTLLEDDI YAFLSPKDYT PISAFCPQEG
CYIASLSKAI CPGLRVAILS VPHGFASLLA RGIFNINVKT SSINIETAAY MIQNEIATEI
IEKKRKEALN RNLTYEKFFP GITPTPLSFS RWLPLSVGLY NFPMERLALE KGLHLFHSNR
FLVGTPPKEK YLRIAVTSAN TTEELEYGLK ILKNFLVEEE GKTADFPIII
//
