ID A0A137Q7P0_9AGAR Unreviewed; 761 AA.
AC A0A137Q7P0;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=acylaminoacyl-peptidase {ECO:0000256|ARBA:ARBA00012917};
DE EC=3.4.19.1 {ECO:0000256|ARBA:ARBA00012917};
DE AltName: Full=Dipeptidyl-peptidase V {ECO:0000256|ARBA:ARBA00032829};
GN ORFNames=AN958_01643 {ECO:0000313|EMBL:KXN83272.1};
OS Leucoagaricus sp. SymC.cos.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN83272.1, ECO:0000313|Proteomes:UP000070249};
RN [1] {ECO:0000313|EMBL:KXN83272.1, ECO:0000313|Proteomes:UP000070249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SymC.cos {ECO:0000313|EMBL:KXN83272.1,
RC ECO:0000313|Proteomes:UP000070249};
RA Hu H.;
RT "Leucoagaricus sp. SymC.cos WGS genome.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Cleavage of an N-acetyl or N-formyl amino acid from the N-
CC terminus of a polypeptide.; EC=3.4.19.1;
CC Evidence={ECO:0000256|ARBA:ARBA00000721};
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the peptidase S9C family.
CC {ECO:0000256|ARBA:ARBA00010040}.
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DR EMBL; KQ962842; KXN83272.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137Q7P0; -.
DR STRING; 1714833.A0A137Q7P0; -.
DR OrthoDB; 2877590at2759; -.
DR Proteomes; UP000070249; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008236; F:serine-type peptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR045550; AARE_N.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR001375; Peptidase_S9.
DR PANTHER; PTHR42776:SF4; ACYLAMINO-ACID-RELEASING ENZYME; 1.
DR PANTHER; PTHR42776; SERINE PEPTIDASE S9 FAMILY MEMBER; 1.
DR Pfam; PF19283; APEH_N; 1.
DR Pfam; PF00326; Peptidase_S9; 2.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000070249}.
FT DOMAIN 25..245
FT /note="Acylamino-acid-releasing enzyme N-terminal"
FT /evidence="ECO:0000259|Pfam:PF19283"
FT DOMAIN 507..604
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
FT DOMAIN 665..755
FT /note="Peptidase S9 prolyl oligopeptidase catalytic"
FT /evidence="ECO:0000259|Pfam:PF00326"
SQ SEQUENCE 761 AA; 83463 MW; B3033A9E609372FF CRC64;
MSLYNRLAEI PVPLSATFLN NEVVQIGYSA RNHLANTKKT LTKIVPLTSG VPTNFPLQEV
GEVVGSAVSP SYNLRANLRE SKQGTTTKRY VEIWSGNRTE VSFEVTDHHQ AFYLDENLST
LVFSPSETAL LYTAEANAPE NGSDDPYAKF RYRPSFGEGF GGKKRPHFFL LRWKSPTDST
STVLKPRLYE IHSESDDILF GQGIFFPTAE ETTIYATGYE YTPNGRLLGI KGCFNRPSGI
WELRFQTQSG DGHDDNHDKK QDSIIYSARK ISGTNSGRSP RILQEGSTSI LYWFASDNGG
PHMSTTTLHS LDITILDTIS TEIVSRTKTV VPVPEALSPN FPGLYPPFNL VIRPFLQPDG
GPTEIITQSQ WGSRTTILSI SPSTGTVRHL TPPEPALFSW SLLATDGKNQ IICSRGSSSI
PYQIVLGTFS DKGLQWLVLD QPDLAPDVLS ALKSIRTSIH PIPGRYPVET IVIRSVEEDD
AQAKPAPLIT VPHGGPHGAM TTAFAAANTA LVLEGYTLSF PNFTGTPGYG QSNIYKLLGQ
CGTLDVEDVH ASTLFLVNDL QLARFGPGEI FVMGGSHGGF ITAHLISQYP DVYSAAVMRN
PVTCCGEVAG TDIPDWYFAE FGFQDDFPIK SSPPLSDLST AQKSPAIPNF DPAPHVTPSI
FNKLYEASPT TALYNYLKER SQAPKASKHL PPVLLHIGLS DQRVSPTQGI TFYHLLKGAG
EEVDMLMFEG EGHPLEGIEA TRVGWESTRD WFKKYGRKVS S
//
