ID A0A137QE76_9AGAR Unreviewed; 466 AA.
AC A0A137QE76;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Chitinase A1 {ECO:0000313|EMBL:KXN85555.1};
GN ORFNames=AN958_11122 {ECO:0000313|EMBL:KXN85555.1};
OS Leucoagaricus sp. SymC.cos.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN85555.1, ECO:0000313|Proteomes:UP000070249};
RN [1] {ECO:0000313|EMBL:KXN85555.1, ECO:0000313|Proteomes:UP000070249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SymC.cos {ECO:0000313|EMBL:KXN85555.1,
RC ECO:0000313|Proteomes:UP000070249};
RA Hu H.;
RT "Leucoagaricus sp. SymC.cos WGS genome.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC {ECO:0000256|RuleBase:RU004453}.
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DR EMBL; KQ962451; KXN85555.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137QE76; -.
DR STRING; 1714833.A0A137QE76; -.
DR OrthoDB; 3203764at2759; -.
DR Proteomes; UP000070249; Unassembled WGS sequence.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF406; GH18 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000070249}.
FT DOMAIN 84..462
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT REGION 49..77
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..77
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 466 AA; 49322 MW; 4B0A4020AFEB3560 CRC64;
MYRRPTISNA TSYNSKLLAV SFYVFLCFIL SFSSFPFASA LPMCGLKPPK SARDATQPPA
NAHPGPGSNN NGTVGGGNST ATEVVITGWY PGWQASSFPP SSISWEKWTH LTYAFALTGP
DTSTVVLNSD DQQVLPTFVE QAHSHGVKAL VSIGGWTGSR YFSSAVATPE NRTTFVGAVT
SLAKNYNLDG IDFDWEYPNK QGIGCNIISP QDSANFLLFL QELRGDPVGK KLYLSAAVSI
TPFMGPDGTP MSDVSAFATY LNHIGIMSYD IWGPWSPSIG PNAPLDDSCA PTQVGSAKSA
VAAWTGARFP ANQIVLGVAS YGHSYKLNSQ SSNFTLFSPF TAYSNPLVPS DGSGGVDICG
NPVPGGGGTD VFDFSQMITA GFLNSDGTAA SGIVYLYDNC SQTPFVNNPN SGVVISYDDA
TSFGAKGRFI NSNALKGFAM WEVAGDEHDV LLDAITQAMD VQATCN
//
