ID   A0A137QS84_9AGAR        Unreviewed;       489 AA.
AC   A0A137QS84;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   27-MAR-2024, entry version 30.
DE   SubName: Full=Guanine nucleotide-binding protein alpha-4 subunit {ECO:0000313|EMBL:KXN90125.1};
GN   ORFNames=AN958_04615 {ECO:0000313|EMBL:KXN90125.1};
OS   Leucoagaricus sp. SymC.cos.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX   NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN90125.1, ECO:0000313|Proteomes:UP000070249};
RN   [1] {ECO:0000313|EMBL:KXN90125.1, ECO:0000313|Proteomes:UP000070249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SymC.cos {ECO:0000313|EMBL:KXN90125.1,
RC   ECO:0000313|Proteomes:UP000070249};
RA   Hu H.;
RT   "Leucoagaricus sp. SymC.cos WGS genome.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the G-alpha family.
CC       {ECO:0000256|ARBA:ARBA00005804}.
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DR   EMBL; KQ962070; KXN90125.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A137QS84; -.
DR   STRING; 1714833.A0A137QS84; -.
DR   OrthoDB; 1864818at2759; -.
DR   Proteomes; UP000070249; Unassembled WGS sequence.
DR   GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IEA:InterPro.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR   Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR001019; Gprotein_alpha_su.
DR   InterPro; IPR011025; GproteinA_insert.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10218; GTP-BINDING PROTEIN ALPHA SUBUNIT; 1.
DR   PANTHER; PTHR10218:SF302; GUANINE NUCLEOTIDE-BINDING PROTEIN ALPHA-8 SUBUNIT-RELATED; 1.
DR   Pfam; PF00503; G-alpha; 1.
DR   PRINTS; PR00318; GPROTEINA.
DR   SMART; SM00275; G_alpha; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR   PROSITE; PS51882; G_ALPHA; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070249};
KW   Transducer {ECO:0000256|ARBA:ARBA00023224}.
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          162..194
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        165..189
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   489 AA;  55918 MW;  2722AAB8C19B39A4 CRC64;
     MLQSSDYDPL TAAMRPPPGE TQEQREEREA AEAEALEVSN RIDAEIKASK QAMKRQKKPI
     RVLVLGQSMS GKTTTIKNFQ MIYAQKSWAE ERSSWHIVIC FNLVRNVNTI ADTLNEETTD
     SILTGRRSSL TEWHRSVLFR LSPLRRIEND LKAFLGAGSS ESVEIHHPNR PNTSDGLRDS
     PSAQQISPPE DAKRPQEFCI WSSSGWKSIL NQVKTRSAQG KESQVPRMVR AVLNSCKDDI
     HLLWNDPVVQ SLLRAKHGRL EETPGFFLND VDRILSTDYT PGDEDIVRAR LRTTGVQEYR
     FTLDKGTGTS RDWVMYDVAT AWIPYFPDIT ALIFLAPVSS FNERLMENPR INRLEDTFVL
     WKTVCSSKIL ANVQLILFMN KTDILRRKLE HGYQVKDHIP EFGGNKNEFS SVLEWFRRVF
     RKLFTDNNSS LNRKFIAHFT NVIDTKATQH TLQAGKFSTS RSESMALRYG CFKVQAAILR
     NDIEEAGLM
//