ID   A0A138AIR1_9ACTN        Unreviewed;       594 AA.
AC   A0A138AIR1;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:KXP10343.1};
GN   ORFNames=AXK60_07775 {ECO:0000313|EMBL:KXP10343.1};
OS   Tsukamurella pseudospumae.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC   Tsukamurella.
OX   NCBI_TaxID=239498 {ECO:0000313|EMBL:KXP10343.1, ECO:0000313|Proteomes:UP000070258};
RN   [1] {ECO:0000313|Proteomes:UP000070258}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 15929 {ECO:0000313|Proteomes:UP000070258};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXP10343.1}.
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DR   EMBL; LSRF01000033; KXP10343.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A138AIR1; -.
DR   STRING; 239498.AXK60_07775; -.
DR   OrthoDB; 5241017at2; -.
DR   Proteomes; UP000070258; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..35
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           36..594
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039464480"
FT   DOMAIN          316..573
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   594 AA;  60807 MW;  03AD0A453E885F50 CRC64;
     MRHSSRRHAP TRPARALPGV ALVIAALAGS LVACSEDDVV TKFATAVSAR DAAHAGNLTS
     DPTSATEGLQ ATFDGMGDAK PTVTVGKDGE DRTLTWSWAL PRQHGVRYTT KIAAGGGKVT
     WAPTLVHPDA VAAGSRLRYA DEKPYTTRVV DRKNAPLMTW QTVTVVNLAP EKAVSAADAL
     ATKLRTADPS VTAAGLRKSV AGKDSPTAVI SLRADDAKRV GPLTGIDGVT VREEGRLLTA
     SPALRSPVIP GLEERWRRDV DAAAGSSVTV VDRDGDPVRL VDTFPAKQIP PVRTTVDAGL
     QRAANAAVAG EKRATMLVAI RPSTGGILAV AQNAAADTQG PVALTGLYAP GSTFKTITTA
     AALDAKITTP DAQLACPGRA TFGDRTIPNE NEFTLGTVPL HTAFAKSCNT TMAGLGTKLG
     DTALTDTAKR FGLGVDFTLP GITTVTGSVP AARTSAERVE ESIGQGRVTA SPFGLAVVEA
     SLAARSTVRP ALFDGEPART DTEALPIDAG VAAALRAAMR ETVTAGTATA LRDIEGLGGK
     TGTAEFGDNT HAHGWFAGIV GDLAFATLVV SGESSGPAVA VSGAFLRGAG GDLP
//