ID A0A138AK79_9ACTN Unreviewed; 1007 AA.
AC A0A138AK79;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Ribonuclease E {ECO:0000313|EMBL:KXP10789.1};
GN ORFNames=AXK60_05755 {ECO:0000313|EMBL:KXP10789.1};
OS Tsukamurella pseudospumae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC Tsukamurella.
OX NCBI_TaxID=239498 {ECO:0000313|EMBL:KXP10789.1, ECO:0000313|Proteomes:UP000070258};
RN [1] {ECO:0000313|Proteomes:UP000070258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15929 {ECO:0000313|Proteomes:UP000070258};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXP10789.1}.
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DR EMBL; LSRF01000023; KXP10789.1; -; Genomic_DNA.
DR RefSeq; WP_068571017.1; NZ_LSRF01000023.1.
DR AlphaFoldDB; A0A138AK79; -.
DR STRING; 239498.AXK60_05755; -.
DR OrthoDB; 9804278at2; -.
DR Proteomes; UP000070258; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0004540; F:RNA nuclease activity; IEA:InterPro.
DR GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR CDD; cd04453; S1_RNase_E; 1.
DR Gene3D; 1.10.10.2480; -; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR006847; IF2_N.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR019307; RNA-bd_AU-1/RNase_E/G.
DR InterPro; IPR004659; RNase_E/G.
DR InterPro; IPR003029; S1_domain.
DR NCBIfam; TIGR00757; RNaseEG; 1.
DR PANTHER; PTHR30001; RIBONUCLEASE; 1.
DR PANTHER; PTHR30001:SF0; RIBONUCLEASE G; 1.
DR Pfam; PF04760; IF2_N; 1.
DR Pfam; PF10150; RNase_E_G; 1.
DR SMART; SM00316; S1; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR PROSITE; PS50126; S1; 1.
PE 4: Predicted;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 420..503
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 73..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 126..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 797..845
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 879..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 137..153
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..240
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 303..349
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..822
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1007 AA; 107181 MW; 4540128C46A5E697 CRC64;
MADNTSPEEQ NNEAREEFPQ KLRVHALARL LGLTSKEVLA HLGDLGFVAR SAHSSIDRSA
AERVRDRIAE LAGGAPEVAD QQVAAEPATA APAEPVEETP SLFSEAAVIE PIAEVAPSTI
DTTVPLFLQP EQVEPAPRKA RAPKKKDVVE DAPEPEAPAV DAPATEQDTE PVAEAAAEPA
ESASSSDDSA DDEGAGNRRR RRGRRGRGRG RGENADEQDG QDQAEQTDGA PAQDASTDEQ
QPEADGAAAA EEKTDEASSD GAEGDDVEDV TDGGSRRRRR RRRRRTGAGE DGAEAASSDD
PPNTVVHERE PRESRQRARR DEVRGISGST RLEAKRQRRR DGRDTVRRRP PILTESEFLA
RREAVDRVMV VRERTGVGPS QGQDGHTVPH PADYTQVAVL EDGVLVEHFV TSSSSASMVG
NIYLGRVQNV LPSMEAAFVD IGRGRNGVLY AGEVNWDAAG LDGNARKIEQ ALKPGDQVLV
QVSKDPVGHK GARLTTQISL AGRFLVYVPG GGSAGISRKL PDTERKRLKE ILKEIVPADA
GVIIRTASEG VSAEELAGDV ARLQAQWAEI EAASSQKGVK ALYEEPDLLV KVVRDLFNED
FSKLVIEGRK AWDTTSKYVG DVAPDLLPRV EKFEKAHADA PDVFATFRID EQLAKAMDRK
VWLPSGGTLV IDRTEAMTVV DVNTGKFTGA GGNLEETVTR NNLEAAEEIV RQMRLRDIGG
MIVVDFIDMV LESNRDLVLR RLTEALGRDR TRHQVSEVTS LGLVQMTRKR IGTGLVEAFS
TPCQACAGRG IIVHDAPVES AGGGEEAGRS GERSEGTGRK KRKRSKSDGA VQAPEAQPAP
AKEPVAHKGE HPMFRAMAAH HDEDGNEVAA PVTEAAAEAP EVFDVAPEAP AAEPEQAPAA
QAAPAAAPPE AAPVAEQTPA EQAPSAPRRR RVARKAPTTT SASAQTIVVD IAIPVPDAPT
APAGDAAGAS VAEPARKRAR RRAAARPAGP AAGGVEGDGA DKADQPV
//
