ID A0A139CGJ4_9EURY Unreviewed; 214 AA.
AC A0A139CGJ4;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Dimethylamine corrinoid protein 2 {ECO:0000313|EMBL:KXS40258.1};
GN ORFNames=AWU59_2612 {ECO:0000313|EMBL:KXS40258.1};
OS Methanolobus sp. T82-4.
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanolobus.
OX NCBI_TaxID=1794908 {ECO:0000313|EMBL:KXS40258.1, ECO:0000313|Proteomes:UP000074030};
RN [1] {ECO:0000313|EMBL:KXS40258.1, ECO:0000313|Proteomes:UP000074030}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T82-4 {ECO:0000313|EMBL:KXS40258.1};
RA Wolfe R., Daly R., Wrighton K.;
RT "Methanolobus T82 Annotated.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: One-carbon metabolism; methanogenesis from dimethylamine.
CC {ECO:0000256|ARBA:ARBA00004890}.
CC -!- SIMILARITY: Belongs to the methylamine corrinoid protein family.
CC {ECO:0000256|ARBA:ARBA00010854}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXS40258.1}.
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DR EMBL; LSRV01000133; KXS40258.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A139CGJ4; -.
DR STRING; 1794908.AWU59_2612; -.
DR PATRIC; fig|1794908.3.peg.2521; -.
DR Proteomes; UP000074030; Unassembled WGS sequence.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0050897; F:cobalt ion binding; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProt.
DR GO; GO:0015948; P:methanogenesis; IEA:UniProtKB-KW.
DR CDD; cd02070; corrinoid_protein_B12-BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR InterPro; IPR003759; Cbl-bd_cap.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR036724; Cobalamin-bd_sf.
DR InterPro; IPR012741; Corrinoid_p.
DR InterPro; IPR048095; Dimeth_corrin_MtbC.
DR InterPro; IPR036594; Meth_synthase_dom.
DR NCBIfam; NF041607; dimeth_corrin_MtbC; 1.
DR NCBIfam; TIGR02370; pyl_corrinoid; 1.
DR PANTHER; PTHR45833; METHIONINE SYNTHASE; 1.
DR PANTHER; PTHR45833:SF1; METHIONINE SYNTHASE; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF02607; B12-binding_2; 1.
DR SMART; SM01018; B12-binding_2; 1.
DR SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR SUPFAM; SSF47644; Methionine synthase domain; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51337; B12_BINDING_NTER; 1.
PE 3: Inferred from homology;
KW Cobalt {ECO:0000256|ARBA:ARBA00023285};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Methanogenesis {ECO:0000256|ARBA:ARBA00022994}.
FT DOMAIN 1..91
FT /note="B12-binding N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51337"
FT DOMAIN 92..214
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
SQ SEQUENCE 214 AA; 22736 MW; A4C3575E69D8FC51 CRC64;
MINEEMFKEL SDAIVSCKKD AVTATVEKAR DEGIPPAEII DKGLAAGMNE VGVLFERGKL
FLPHVMMAAG AMEAGVALLE KDMPKDAASK KLGIIVNGTV EGDVHDIGKS IVSTMLQSAG
FEVHDIGRDV PLQDFIDKAK ETSANMIGMS ALMTTTLPGQ KDVIEMLKEQ GMRDDVKVMV
GGAPATEAWA NKIGADCYAE NASEAVAKAK ELLL
//
