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Database: UniProt
Entry: A0A139DCW4_9ALTE
LinkDB: A0A139DCW4_9ALTE
Original site: A0A139DCW4_9ALTE 
ID   A0A139DCW4_9ALTE        Unreviewed;       483 AA.
AC   A0A139DCW4;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   27-SEP-2017, entry version 11.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AWU57_4310 {ECO:0000313|EMBL:KXS51306.1};
OS   Marinobacter sp. T13-3.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC   Alteromonadaceae; Marinobacter.
OX   NCBI_TaxID=1794906 {ECO:0000313|EMBL:KXS51306.1, ECO:0000313|Proteomes:UP000073748};
RN   [1] {ECO:0000313|EMBL:KXS51306.1, ECO:0000313|Proteomes:UP000073748}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T13-3 {ECO:0000313|EMBL:KXS51306.1};
RA   Wolfe R., Daly R., Wrighton K.;
RT   "Marinobacter-3 T13 Annotated.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KXS51306.1}.
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DR   EMBL; LSRT01000594; KXS51306.1; -; Genomic_DNA.
DR   PATRIC; fig|1794906.3.peg.5789; -.
DR   Proteomes; UP000073748; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000073748};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000073748}.
FT   DOMAIN      180    310       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      391    460       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     188    195       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   483 AA;  54940 MW;  3CE8C3CC983E32C7 CRC64;
     MWHQCLEVLR DEFPAQQFNT WLRPLQSDLR EGQLMLFAPN RFVMDWVNQK YLRRIEEVLK
     DLNGGQAPRV VMKVGSAPKE SAPVDRSVDR PEPPSAVEET GRTVTEEEKS VAATVPAATT
     AAVSPERRRN QQRRDVQVEG DIKHQSFLNE SFTFETFVEG KSNQLARAAS MQVAENPGGA
     YNPLFLYGGV GLGKTHLMHA IGNEIVRRNP GAKVAYLRSE RFVADMVKAL QLNAINEFKR
     YYRSVDALLI DDIQFFARKE RSQEEFFHTF NALLEGGQQV IVTCDRFPKE IVDMEERLKS
     RFGWGLTVMV EPPELETRVA ILMKKAEQAN VKLSSEAAFF IAQKIRSNVR ELEGALRLVI
     ANAHFTGSEI TPPFIRESLK DLLALHEKQV SIDNIQRTVA EYYKIKVADL LSKRRTRTVT
     RPRQVAMSLA KELTNHSLPE IGDAFGGRDH TTVLHACKKI IELQETDPGI REDYQNFMRL
     LTT
//
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