ID   A0A139H368_9PEZI        Unreviewed;       858 AA.
AC   A0A139H368;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   22-FEB-2023, entry version 14.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=AC578_7419 {ECO:0000313|EMBL:KXS96861.1};
OS   Pseudocercospora eumusae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX   NCBI_TaxID=321146 {ECO:0000313|EMBL:KXS96861.1, ECO:0000313|Proteomes:UP000070133};
RN   [1] {ECO:0000313|EMBL:KXS96861.1, ECO:0000313|Proteomes:UP000070133}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 114824 {ECO:0000313|EMBL:KXS96861.1,
RC   ECO:0000313|Proteomes:UP000070133};
RA   Chang T.-C., Salvucci A., Crous P.W., Stergiopoulos I.;
RT   "Comparative genomics of the Sigatoka disease complex on banana suggests a
RT   link between parallel evolutionary changes in Pseudocercospora fijiensis
RT   and Pseudocercospora eumusae and increased virulence on the banana host.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC       multimeric enzyme that catalyzes the translocation of protons across
CC       the membranes. Required for assembly and activity of the V-ATPase.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXS96861.1}.
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DR   EMBL; LFZN01000161; KXS96861.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A139H368; -.
DR   STRING; 321146.A0A139H368; -.
DR   OrthoDB; 1967517at2759; -.
DR   Proteomes; UP000070133; Unassembled WGS sequence.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR   PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW   ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070133};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM        424..449
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        470..491
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        551..569
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        581..604
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        647..668
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        760..778
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        790..812
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   COILED          101..128
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   858 AA;  97634 MW;  4AA7BA1C391757FE CRC64;
     MAPNSESLFR SQDMTLTQLY VANEIGREVV SALGELGVMQ FRDLNPETTA FQRTFTQEIR
     RLDNVERQLN YFRSQIEKNS IEMRSIYDFS DAIAAPSASE IDELADRSQQ LEQRIQSLNE
     SYETLKKREV ELTEWRWVLR EAGGFFDRAR GQTEEIRQSI DSSDDAPLLR DVENANGSAE
     GGQQSFSVMN IGFVAGVIPR ERMGAFERIL WRTLRGNLYM NQSEIPDAII DPEKNEEHHK
     NVFVIFAHGK EIIAKIRKIS ESLGADIYNV DENSELRRDQ IHEVNSRLQD LGNVLGNTKR
     TLDAELTQIG RSLAAWMIVI KKEKSVYQTL NRFSYDPARK TLVAEAWCPT SSLGLIKSTL
     QDVNERAGLS VPTIVNQIKT SKTPPTYNKT NKFTLGFQTI IDAYGTAKYT EVNPGLPTIV
     TFPFLFAVMF GDFGHGAIMT LAAIAMIIFE KPLQRGKQDE LFGMAFYGRY IMLMMGIFSM
     YTGLIYCDAF SKEIPLFSSM WEWDFPDNYI PDKTTITAKR VEGYTYPFGL DWRWHDTEND
     LLFSNSYKMK LSIIMGWAHM TYSLCLSYVN ARHFKSNIDI WGNFIPGMIF FQGIFGYLVL
     TIVWKWCVDW YAIGEQPPNL LNMLIYMFLS PGTVEERLYS GQGGVQVILV LLAVIQVPIM
     LFLKPFYLRW EHNRARAKGY RGIGETTAVS ALDDAGDHAN GDAGRPSFAE SDLDGAVITQ
     DIGGDEHEEF EFSEIMIHQV IHTIEFCLNC VSHTASYLRL WALSLAHQQL SIVLWSMTLK
     NAFAFEGATG IVVIFLAFVV WFALTIAVLV VMEGTSAMLH SLRLHWVEAM SKHFIGEGVA
     FEPFSFKQML DDEMTELK
//