ID   A0A139HPH9_9PEZI        Unreviewed;       807 AA.
AC   A0A139HPH9;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=HpcH/HpaI aldolase/citrate lyase domain-containing protein {ECO:0000259|Pfam:PF03328};
GN   ORFNames=AC578_7900 {ECO:0000313|EMBL:KXT04303.1};
OS   Pseudocercospora eumusae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC   Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX   NCBI_TaxID=321146 {ECO:0000313|EMBL:KXT04303.1, ECO:0000313|Proteomes:UP000070133};
RN   [1] {ECO:0000313|EMBL:KXT04303.1, ECO:0000313|Proteomes:UP000070133}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 114824 {ECO:0000313|EMBL:KXT04303.1,
RC   ECO:0000313|Proteomes:UP000070133};
RA   Chang T.-C., Salvucci A., Crous P.W., Stergiopoulos I.;
RT   "Comparative genomics of the Sigatoka disease complex on banana suggests a
RT   link between parallel evolutionary changes in Pseudocercospora fijiensis
RT   and Pseudocercospora eumusae and increased virulence on the banana host.";
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HpcH/HpaI aldolase family.
CC       {ECO:0000256|ARBA:ARBA00005568}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXT04303.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LFZN01000022; KXT04303.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A139HPH9; -.
DR   STRING; 321146.A0A139HPH9; -.
DR   OrthoDB; 2785075at2759; -.
DR   Proteomes; UP000070133; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.20.60; Phosphoenolpyruvate-binding domains; 1.
DR   InterPro; IPR005000; Aldolase/citrate-lyase_domain.
DR   InterPro; IPR015813; Pyrv/PenolPyrv_Kinase-like_dom.
DR   InterPro; IPR040442; Pyrv_Kinase-like_dom_sf.
DR   PANTHER; PTHR30502; 2-KETO-3-DEOXY-L-RHAMNONATE ALDOLASE; 1.
DR   PANTHER; PTHR30502:SF0; PHOSPHOENOLPYRUVATE CARBOXYLASE FAMILY PROTEIN; 1.
DR   Pfam; PF03328; HpcH_HpaI; 1.
DR   SUPFAM; SSF51621; Phosphoenolpyruvate/pyruvate domain; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070133}.
FT   DOMAIN          33..246
FT                   /note="HpcH/HpaI aldolase/citrate lyase"
FT                   /evidence="ECO:0000259|Pfam:PF03328"
FT   REGION          414..502
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          666..686
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        428..442
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        443..476
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        481..502
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        668..686
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   807 AA;  88246 MW;  9FC74D23258EB79C CRC64;
     MQAANRLQKA LKSGGPSLGG WQMLPGANLS RAIARTPGLD WICVDTEHGN ISDAEMHESV
     AAIAACGVSP VVRLPDGQHW MIKRALDAGA HGIIIPLLQS VEDARNVVKF SKFPPNGNRG
     LGSPFAMEKF AEQVSNPKEI SISQYFQEAN SSIVVIVQIE TASALEQIDQ IAAVPGIDVC
     FIGPVDLGNS IGHPPENIGV YAPELENAIS KIHAATQAAG KWTAIYTGSG EQAKRYVNLG
     FNMVNTMNDV GAIRASFAHA AAAAAVKQKP LMRPRVVDFG VTLIAYCALS TTFTKQLAKL
     KLDLNAPNYF PQPFLPQRRR ARLLNSMCFI DIIHYICGGE DQILVERCVL PSLCIPHVRR
     TLHSTTVCEL CGRAWELSAL TEEAYEAVTT PLIESRQANG GYFGYFMQSQ PARPLLCQPQ
     TPPSSDEIEV HELSRKQSPK VVNDRPKMST NTTGPAQHAQ ESDSPAKASK DVTSTSFDAK
     APEPVDEKLM PADGKPIAED DRRPKFDWKG ALSTLATSAV GIATFPGSGT AAMRVNYYQR
     LITEQAIDAL PKEAQRVLFV QLTILALNTD SSLGTPSSNI ENYKRGIQFV LRMLGGKDIG
     SGEPQPSLSS VTDPDRQAEI MTLAVQLAEL FDKHGLLHVC PDVFRGTWEG DFDDEDLEFE
     QEMKSHFQRL QNEPAPSPSP ENTPSVSDTQ IIVTVEALTK LQSRYPDLFA LDTKYLELLA
     EKANLEACVI ESKDDLSKLR KVVEDEAGVM RGQSELKRIY GAADNVRTAI GRHADELKEF
     IDIKSELCEV EIKIAVHLAE KKIRTEL
//