ID A0A139WGR7_TRICA Unreviewed; 2257 AA.
AC A0A139WGR7;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 26.
DE RecName: Full=Phosphoenolpyruvate synthase {ECO:0008006|Google:ProtNLM};
GN Name=AUGUSTUS-3.0.2_34713 {ECO:0000313|EMBL:KYB27089.1};
GN ORFNames=TcasGA2_TC034713 {ECO:0000313|EMBL:KYB27089.1};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:KYB27089.1, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:KYB27089.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB27089.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:KYB27089.1, ECO:0000313|Proteomes:UP000007266}
RP GENOME REANNOTATION.
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB27089.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
CC -!- SIMILARITY: Belongs to the PEP-utilizing enzyme family.
CC {ECO:0000256|ARBA:ARBA00007837}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ971344; KYB27089.1; -; Genomic_DNA.
DR STRING; 7070.A0A139WGR7; -.
DR EnsemblMetazoa; TC034713_001; TC034713_001; TC034713.
DR eggNOG; ENOG502QS3J; Eukaryota.
DR InParanoid; A0A139WGR7; -.
DR Proteomes; UP000007266; Linkage group 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:InterPro.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.30.470.20; ATP-grasp fold, B domain; 1.
DR Gene3D; 3.50.30.10; Phosphohistidine domain; 1.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR008279; PEP-util_enz_mobile_dom.
DR InterPro; IPR036637; Phosphohistidine_dom_sf.
DR InterPro; IPR002192; PPDK_AMP/ATP-bd.
DR PANTHER; PTHR43615; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR PANTHER; PTHR43615:SF1; PHOSPHOENOLPYRUVATE SYNTHASE-RELATED; 1.
DR Pfam; PF00391; PEP-utilizers; 1.
DR Pfam; PF01326; PPDK_N; 1.
DR SUPFAM; SSF56059; Glutathione synthetase ATP-binding domain-like; 1.
DR SUPFAM; SSF52009; Phosphohistidine domain; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..25
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 414..719
FT /note="Pyruvate phosphate dikinase AMP/ATP-binding"
FT /evidence="ECO:0000259|Pfam:PF01326"
FT DOMAIN 1210..1281
FT /note="PEP-utilising enzyme mobile"
FT /evidence="ECO:0000259|Pfam:PF00391"
SQ SEQUENCE 2257 AA; 255932 MW; B73834CFF197F0FE CRC64;
MELLLNFCYY VTLFLIPISL YVLVFQHRTK NRFYTNRDWF YIIKFLIAKS AVKKHQNKFK
TKINITESPI EIRTENYCDN YFIYGADQKG NSLSLRFIIG SGLVGEVFLC LRLSTGAIYT
FPGEKKTKQY NLSDWHWKTK DLHLEILEPF KRHRVTFNGL LSNATNDIEH VRFNLTWIAT
NAPRFHPQDA ATDLLTNALA QHPWRDGDWL SLLGDECGYE QFGALHGFIR GDSFKDDFFV
NLPSCRTRFW GTAEKLAVSK CLHLFVAGHD GTLISIWVKS LKHGCHGLQY GNVVMTNGTI
QPITASDIRF DCLGQNSQLP ETFLIHIYAL KQTFRIVFHT NTIKTIVDGH DLSNIPADCD
LNTQQGKSLV ELWQGVKNTS RDKPLKPLLI ENKSKTLPTC YVISLDDESA KIVNLSGGKG
CSLAMLTCLK SDDFIVPNGF IITVNAFNKQ LEMNFNMKKA VSILDDICCG RSLGDLEHAC
AQTIKTFESE KIIPEVASVI LQAFRNLKPR PTDRFAVRSS AIGEDSEDLS AAGQNSTFLG
CSTFASILQS VSACWASLYT NQSVRYRHKH GIAIPSQMAV VVQKMVQADC AGVLFTCHPS
TGNPAHIVIT ANHGLGESVV SGRSEPDTII LERTFDNDVT IQSKTLGLKN KIVKMTTDGE
GVVECDGLQG FSLTDNQALV LGRVGVALEE KMGGARDIEW AFSQGRLYLL QARPITTLNL
WTDYELLHEF DVATLSDDVV YTVANTGEIL PGAISTLTLS TVVKAIDKSI QISVEGHSNE
YSLKCLGTFQ GHLFVDVITG IHRRVKNKIE LISKIVDLAI FGHPIINEKI HYLSLNRFGP
IGSLEQFKEL YTMIKLAWCN EKNAKMSKTI NETYQVGIDT TRDTLKDIYN KIDKSLNKMA
EVLLLHCYTT RTSVSYQIFA MTVLAENAQD FTIDHYNDIA MLLASCDEVI SAEIPNTLAN
ITRILNENHQ NMKFAEIDPN LGRKWLKDNS PEASKIFEQF IKNHGHRALR EFDIFNETWG
TNPVEVIKMI QTNCRSKSPK QEKTIKPIDE VIAGLVSPTK TSTRKFLKFL MNKSRRAVGL
REQTKSESIR FVDKLRQSYR ILGQKMAFQG LIPEPDLIFH LSHYEIGQIL DKSDRNPIII
TKALRRQKLY PKWDRLKFPE ISYGIPLPET RDFIPRSGSG TVKCEGTPVC FGIIQARACV
ITDLKEIDQL HEGDVLITYC TDIGWSPYFP MLGGIVTELG GLVSHGAVIA REYGLPCIVG
AKGATKMFKT GDLVILSGEN GTVERCATNI PPIFDHFTPK CVFTLPKCSH NLTVTKSRFF
HIRPPNRAKL YTDGENAYAY IILPKIVKFT TCYNAPKQIK TSEQFDEFLN RNWRDSCASD
IVEAFECIKD YCVVKDINVG DVRFDKLVDG LMDHCEKLTD EELLRLLTLL TEYPQCESST
THNYHDIWSC LDDICCWKMS NWNFQKLFTF AEIWYRLNLG RLSDFVYEVI DKAVKKSHRL
PNEFLVYICF YLNVARKKEV PFDFEHTLAE RIDEFNVEEL TIVAMAYFKT KSKVKLLPIL
NAMIRAINAN CDSINEISLT AMLKTIRLSQ HIQTADQIPP LLDNLMPQIP RLSKLAILHI
ALLGTSLQIK HEKSLTRCAQ SILEDIENVR LKDLERILLA CSMFNIDTNP SIFDLVSNEL
KKSNRQQESI QYNRSLGSTI HYLTFRQVYP FELINKVLDT EYINDVYGNS SRNFPRELFS
LDCSLEIECP NYSGNRLDPV KKTKSAKWLT DYTPSHTQFK RLTLADKFYL DVAEHVSIAI
GQNCVRHYHV LPHFSKSDIV ICRDLSDGNF VVPKLLDRYV LGDIMRPFGD FDWFAFIVMT
TNLTVRGRNE PLGSMVMKER QLRRIGFKPI FVYWSEFGEL GTEKEKVKNL FQKIMNKLYK
PKVTFSDSLT KISKNVRREI RPRSRSVYTT SSYISDDLGT PRDLKYENPS SWSPYVPKPI
VVKNYYPDDL NSETWADDGG YMGGTTITPH GVISLRLHDR IRVDISLDRA IRIINMKNYI
VLALNASGSS SALIHPNGRV LQYGSRVEIL AHDGQGNNKY AKMWYKGVSF TSDQCALVYL
VDSAGTRTTT DTFTDLTGDI TLDVFYNRPN CGLDFACVTP GTHLVNEAVS VLQSANYWLT
EDRTDNWIIN NVRISQTADG LVRVGRNSNK FSLRTSPTNG SASVSSPYLH CTGSMGQTRH
LFVRRGERRM HYDGTTFIVR NAGHSAGFDE RHQLKVY
//
