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Database: UniProt
Entry: A0A142HN57_9SPHI
LinkDB: A0A142HN57_9SPHI
Original site: A0A142HN57_9SPHI 
ID   A0A142HN57_9SPHI        Unreviewed;       474 AA.
AC   A0A142HN57;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   05-JUL-2017, entry version 12.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=A0256_02225 {ECO:0000313|EMBL:AMR30315.1};
OS   Mucilaginibacter sp. PAMC 26640.
OC   Bacteria; Bacteroidetes; Sphingobacteriia; Sphingobacteriales;
OC   Sphingobacteriaceae; Mucilaginibacter.
OX   NCBI_TaxID=1300914 {ECO:0000313|EMBL:AMR30315.1, ECO:0000313|Proteomes:UP000073092};
RN   [1] {ECO:0000313|EMBL:AMR30315.1, ECO:0000313|Proteomes:UP000073092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PAMC 26640 {ECO:0000313|EMBL:AMR30315.1,
RC   ECO:0000313|Proteomes:UP000073092};
RA   Park H.;
RT   "Mucilaginibacter sp. genome sequencing.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP014773; AMR30315.1; -; Genomic_DNA.
DR   RefSeq; WP_067187629.1; NZ_CP014773.1.
DR   EnsemblBacteria; AMR30315; AMR30315; A0256_02225.
DR   KEGG; mup:A0256_02225; -.
DR   KO; K02313; -.
DR   Proteomes; UP000073092; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000073092};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000073092}.
FT   DOMAIN      170    300       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      381    450       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     178    185       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   474 AA;  53777 MW;  AE7BE009B656F163 CRC64;
     MEKTCTTVWN SCLLIIKDNI PAQSFKTWFE PIKALRMEGS VLTIQVPSLF FYEWLEEHYV
     GLLRKTIKKQ LGDEGRLEYN IVVEQSSAKP YTTNMPSNGN GAESKNQSMP IPISINKDIK
     NPFVIPGLKK LNVDPQLNRN YTFESFVEGD CNRLARSAGY AVAAKPGGTS FNPLMIYGGV
     GLGKTHLAQA IGNEIKRSLP DKLVLYVSCE KFTQQFVDAL KHNNINDFVN FYQAIDVLIM
     DDVHNFAGKE KTQDFFFHIF NHLHQSGKQL IITSDKAPKD LAGLEERLLS RFKWGLSADL
     QIPDLETRMA ILKNKIYQDG IELSNDVIEY VAHNIDNNVR ELEGAMVSLL AQSTLNRKEI
     DLNLAKQMLK NFVKNSAKEI SMEYIQSLVC EYFEVPIDMV KSQTRKREIV QARQISMYLA
     KAHTKSSLKS IGNFFGGRDH STVIYACQTV EDLIDTDKKF KGYVADIQKK LKMS
//
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