GenomeNet

Database: UniProt
Entry: A0A142L2A3_9BACT
LinkDB: A0A142L2A3_9BACT
Original site: A0A142L2A3_9BACT 
ID   A0A142L2A3_9BACT        Unreviewed;       478 AA.
AC   A0A142L2A3;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   25-OCT-2017, entry version 13.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=AEM51_04240 {ECO:0000313|EMBL:AMS26349.1};
OS   Bacteroidetes bacterium UKL13-3.
OC   Bacteria; Bacteroidetes.
OX   NCBI_TaxID=1690483 {ECO:0000313|EMBL:AMS26349.1, ECO:0000313|Proteomes:UP000075224};
RN   [1] {ECO:0000313|EMBL:AMS26349.1, ECO:0000313|Proteomes:UP000075224}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=UKL13-3 {ECO:0000313|EMBL:AMS26349.1};
RA   Noorani M.;
RL   Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP012155; AMS26349.1; -; Genomic_DNA.
DR   EnsemblBacteria; AMS26349; AMS26349; AEM51_04240.
DR   KEGG; bbau:AEM51_04240; -.
DR   PATRIC; fig|1690483.4.peg.897; -.
DR   KO; K02313; -.
DR   Proteomes; UP000075224; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000075224};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075224}.
FT   DOMAIN      172    301       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      383    452       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     180    187       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   478 AA;  54542 MW;  E640549C6043FFD1 CRC64;
     MSEKSAENVW NNCLKLIQDN VSPQSFKTWF EPIKPIKLEN KVLTIQVPSQ FFYEWLEEHY
     VTLLKKTLKQ ELGTGSRLEY NIIVENSTNN ANPYVVNLPG STNAKSDTQN INVPLNLSSN
     IKNPFIIPGL KKINIDSNLN SNLTFDNFIE GDCNRLARSA GYAVANKPGG TSFNPLMIFS
     DTGLGKTHLV QAIGNMIKQN SKNKIVLYVP VEKFCNQFVD SIRNNSNQDF VNFYQHVDVW
     IVDDVQFLEN KQKTQEIFFT IFNHLHQLGK QIILTSDRAP KDLKGMDERL LSRFKWGLSC
     DLQGPDFETR LAILEHMMYA DGINLSRDVV EYVAHNINTN VRELQGALVS LLAQSSLNRK
     EVTLDLAKQI LKNFVKNSSR EISIEFIQKL VCDYFTIPVE LVKSKTRKRE IVQARQISMF
     YAKDLTKSSL KTIGMHFGGR DHSTVIHACQ TVNDLIETDK KFKADIEEIG KRIKINLV
//
DBGET integrated database retrieval system