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Database: UniProt
Entry: A0A143B2H0_9DELT
LinkDB: A0A143B2H0_9DELT
Original site: A0A143B2H0_9DELT 
ID   A0A143B2H0_9DELT        Unreviewed;       451 AA.
AC   A0A143B2H0;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   25-OCT-2017, entry version 14.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=DBW_0001 {ECO:0000313|EMBL:AMV70402.1};
OS   Desulfuromonas sp. DDH964.
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Desulfuromonadaceae; Desulfuromonas.
OX   NCBI_TaxID=1823759 {ECO:0000313|EMBL:AMV70402.1, ECO:0000313|Proteomes:UP000075994};
RN   [1] {ECO:0000313|EMBL:AMV70402.1, ECO:0000313|Proteomes:UP000075994}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DDH964 {ECO:0000313|EMBL:AMV70402.1,
RC   ECO:0000313|Proteomes:UP000075994};
RA   Badalamenti J.P., Bond D.R.;
RT   "A little goes a long way: Capturing complete genomes from a deep
RT   subsurface metagenome with long reads.";
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00911680}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
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DR   EMBL; CP015080; AMV70402.1; -; Genomic_DNA.
DR   RefSeq; WP_066729553.1; NZ_CP015080.1.
DR   EnsemblBacteria; AMV70402; AMV70402; DBW_0001.
DR   KEGG; deu:DBW_0001; -.
DR   PATRIC; fig|1823759.3.peg.1; -.
DR   KO; K02313; -.
DR   Proteomes; UP000075994; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747950};
KW   Complete proteome {ECO:0000313|Proteomes:UP000075994};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00911664};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00747996};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00911684};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00747895};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075994}.
FT   DOMAIN      148    276       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      359    428       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     156    163       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   451 AA;  51551 MW;  188738623CF90D0E CRC64;
     MNKLWQETVS HLEKTLNPQH FSTWIKPVRF VSLKKDLLIL EVPNRFFFDW IRDHYARLIQ
     ETVSQIGAVS YKITFQIASL PEKGNHQSKD EKVNPASPVE PVRETLPREW NGSYNLNPKY
     VFDEFVSGSS NQFAYAAARA VANNPATTYN PLFIYGGVGL GKTHLINAVG NAILSRNPEM
     KVCYYTSEKF MNELINSLRY AKMDEFRNKF RSMDVLLIDD VQFIAGKERT QEEFFHTFNS
     LYESHKQIVV TSDKFPKEIP GLEERLRSRF EWGLIADIQS PDVETKLAIL KMKAESNFID
     LPEDVAQFLA NSVSSNVREL EGFLIRIGAF ASLTSTKVTL EMAREVLKDI LVEKNRELTV
     EEIQKAVASH YGLKIADLKS PKRLKTLVLP RQVAMYLSRQ MTSMSYPDIG EKFGGKDHST
     IIHAIKKIEK AMIEDLQLRS ALTAIKNTLS Q
//
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