ID A0A143G8E9_9GAMM Unreviewed; 945 AA.
AC A0A143G8E9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Cation:proton antiporter {ECO:0000313|EMBL:AMW80435.1};
GN ORFNames=AMD27_14560 {ECO:0000313|EMBL:AMW80435.1};
OS Acinetobacter sp. TGL-Y2.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Moraxellales; Moraxellaceae;
OC Acinetobacter.
OX NCBI_TaxID=1407071 {ECO:0000313|EMBL:AMW80435.1, ECO:0000313|Proteomes:UP000076238};
RN [1] {ECO:0000313|Proteomes:UP000076238}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TGL-Y2 {ECO:0000313|Proteomes:UP000076238};
RA Zhang G.;
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}.
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DR EMBL; CP015110; AMW80435.1; -; Genomic_DNA.
DR RefSeq; WP_067661833.1; NZ_CP015110.1.
DR AlphaFoldDB; A0A143G8E9; -.
DR STRING; 1407071.AMD27_14560; -.
DR KEGG; acv:AMD27_14560; -.
DR OrthoDB; 9811798at2; -.
DR Proteomes; UP000076238; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-KW.
DR GO; GO:0006811; P:monoatomic ion transport; IEA:UniProtKB-KW.
DR InterPro; IPR007182; MnhB.
DR InterPro; IPR025383; MrpA_C/MbhD.
DR InterPro; IPR046806; MrpA_C/MbhE.
DR InterPro; IPR001750; ND/Mrp_mem.
DR InterPro; IPR001516; Proton_antipo_N.
DR PANTHER; PTHR43373:SF1; ANTIPORTER SUBUNIT MNHA2-RELATED; 1.
DR PANTHER; PTHR43373; NA(+)/H(+) ANTIPORTER SUBUNIT; 1.
DR Pfam; PF13244; MbhD; 1.
DR Pfam; PF20501; MbhE; 1.
DR Pfam; PF04039; MnhB; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR Pfam; PF00662; Proton_antipo_N; 1.
DR PRINTS; PR01434; NADHDHGNASE5.
DR PRINTS; PR01435; NPOXDRDTASE5.
PE 4: Predicted;
KW Antiport {ECO:0000256|ARBA:ARBA00022449};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000076238};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000320};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..51
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 80..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..129
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 135..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 197..223
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..295
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 362..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 462..484
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 504..529
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 579..600
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 638..656
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 662..680
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 700..718
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 756..775
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 796..817
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 823..844
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 864..883
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 903..927
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 68..105
FT /note="NADH-Ubiquinone oxidoreductase (complex I) chain 5
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00662"
FT DOMAIN 130..413
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
FT DOMAIN 622..685
FT /note="MrpA C-terminal/MbhD"
FT /evidence="ECO:0000259|Pfam:PF13244"
FT DOMAIN 695..779
FT /note="MrpA C-terminal/MbhE"
FT /evidence="ECO:0000259|Pfam:PF20501"
FT DOMAIN 798..924
FT /note="Na+/H+ antiporter MnhB subunit-related protein"
FT /evidence="ECO:0000259|Pfam:PF04039"
SQ SEQUENCE 945 AA; 101878 MW; 17DBDC98E561DE4A CRC64;
MDTSVLPIII LLPLILGTFF VLWLKKFSRG ATALGAIGVS LSSFILLLTQ AKNVLNGHAV
VEHWSWLPQL GIDLSFRLDA LSLIFALLIS GIGTLIYIYA YYYLNPKNSL SKLYALLMLF
MAAMLGISLS NNLMILLVFW EMTSISSFLL VGYWSNYDAA QRGSRMALTI TGLGGLAMLG
GFILLGQITG TYQIDQIITM TSTIQASSLF VPTLLLILLG AFTKSAQFPF HFWLPNAMAA
PTPVSAYLHS ATMVKAGIFL LARLMPIFVG SALYHNLVTT VGLFTLCMAA FFAIFKEDLK
GLLAYSTISH LGLIVCLLGI GSPLAVAAAV FHIINHATFK AALFMIAGII DHETGTRDIR
KLSGIWQLLP FTATLTMITA AAMAGVPLTN GFLSKEMFFT ELLANLSGGI AVLAAIVATL
AGLFAVAYSA RLVHGVFFDG DVGKGVPNKD AHEPHMGMRA PAMILAALCI AVGILPALLL
EPIVNAGARA SINQATFEGV HLAIWHGFNL PLLMSAIALV GGLIFYFALA KGSRIREIDL
DPSLGKLQGK VLFESFLKHL LLNSRKLKRA TETGSLQHYL LWIVVFAIAL VAMPLLGQGI
STGTRELTHA PIVAIVLWLL LFSACWMMLW FHHERIKAVL ISGAVGLVVT LVFVTLSAPD
LALTQITVDV VTTVLLLMSL SLLPQLTPYE SSRSRRWRDA AIAIIGGLGI GWIAWLILTR
DHNSISWFFL QQSLPLGGGS NVVNVILVDF RGFDTFGEIT VLGIAAIGAL CMMDGMRAHG
TTITQGLTYR FNPSPLMFRM TASWVLPIAL VVSLYIFLRG HNLPGGGFIA GLITSMALVI
QYIALGQEQA ENMLRAKSGR LYEIWIGVGL MIAGLTGIAA WLWGRPFLTS AHIYVEPVLL
GKMHLASAAA FDVGVYVTVV GAAMLMISVL SDSRNTSITG PVPKG
//
