ID   A0A143Z1S7_9LACT        Unreviewed;       770 AA.
AC   A0A143Z1S7;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Competence protein {ECO:0000313|EMBL:CZR04688.1};
GN   ORFNames=TR210_2140 {ECO:0000313|EMBL:CZR04688.1};
OS   Trichococcus ilyis.
OC   Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC   Trichococcus.
OX   NCBI_TaxID=640938 {ECO:0000313|EMBL:CZR04688.1, ECO:0000313|Proteomes:UP000076878};
RN   [1] {ECO:0000313|EMBL:CZR04688.1, ECO:0000313|Proteomes:UP000076878}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Trichococcus_R210 {ECO:0000313|EMBL:CZR04688.1};
RA   Wen L., He K., Yang H.;
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; FJNB01000017; CZR04688.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A143Z1S7; -.
DR   STRING; 640938.TR210_2140; -.
DR   Proteomes; UP000076878; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR   CDD; cd07731; ComA-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR035681; ComA-like_MBL.
DR   InterPro; IPR004477; ComEC_N.
DR   InterPro; IPR004797; Competence_ComEC/Rec2.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   NCBIfam; TIGR00360; ComEC_N-term; 1.
DR   NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR   PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR   PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR   Pfam; PF03772; Competence; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        14..31
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        38..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        227..250
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        262..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        315..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        351..374
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        380..405
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        425..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        451..468
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        477..494
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          507..718
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   770 AA;  85643 MW;  047FE4E95F3AD7C6 CRC64;
     MLVFPITVIW FDRANFFAWA LLGAVLLRLF LMQSRSLNVV AAAVVAASLL SLHVHNWSGG
     SEFSLQEAEA GQSAVLRLDP NDVRINGDLL SGEALLRMGG KEERVYFYYT IKTEEEKISW
     EQQRSGRYFA AEVELEAPEA ERNLHQFDFK EYLARKDIHW VATIDALQFQ REDRSALAWL
     GSIRRAIILM LEQLPAGQTT DYIQTMLFNQ AHAIAGETLD SYRGIGLLHL FSISGMHIQL
     LLAQVRFLLL RMRVSHETTN KLLVVFLVGY GVLTGWGIGV FRAICTHFIL LIGRIFGRPV
     EAKDAFALTV LITVLYNPLL IYSASFQLSY LLAALLYFIA PVSAEWKMNG FLKDICLTAL
     MTIASFPVVA YHFFEVSWLG IFMNVIFSFF FSWLLFPLFW TLFLLVLVSP RNPLLGLFCS
     VSDKLLSALE IFAGTAADLD FAALVTGRPH AFYFALVGAA VAMLLLNIEK KQKDNRVLGF
     LIAAIGLFAF SPQLSPAGKV VMVDVGQGDA ILIITPFHHR AVLIDTGGMI AFEKEAWQVR
     ETSATAGKKL VMAIKAEGVR KLDMVFLTHA DQDHVGSLRE LAEGLPIASV YFPKGAEGNE
     EFAAVLLEMQ KEKRVGIYPV LGRVDLPISA DMVFRILAPL SPGAGGNEDS LIIHAAIGGL
     DWLFTGDLGE EGEELLLHTY PNLKTDVLKI GHHGSATSSS ESFLDQLQPK VALISAGKNN
     RYGHPEAEVL ERLELRNIPV YRTDQQGAVH FLYGSGETEW RIVLEQQKNK
//