ID A0A145Q4U5_9BACT Unreviewed; 591 AA.
AC A0A145Q4U5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE RecName: Full=Mur ligase {ECO:0008006|Google:ProtNLM};
GN ORFNames=GEMMAAP_14720 {ECO:0000313|EMBL:AMW06892.1};
OS Gemmatimonas phototrophica.
OC Bacteria; Gemmatimonadota; Gemmatimonadetes; Gemmatimonadales;
OC Gemmatimonadaceae; Gemmatimonas.
OX NCBI_TaxID=1379270 {ECO:0000313|EMBL:AMW06892.1, ECO:0000313|Proteomes:UP000076404};
RN [1] {ECO:0000313|EMBL:AMW06892.1, ECO:0000313|Proteomes:UP000076404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AP64 {ECO:0000313|EMBL:AMW06892.1,
RC ECO:0000313|Proteomes:UP000076404};
RX PubMed=24821787; DOI=10.1073/pnas.1400295111;
RA Zeng Y., Feng F., Medova H., Dean J., Koblizek M.;
RT "Functional type 2 photosynthetic reaction centers found in the rare
RT bacterial phylum Gemmatimonadetes.";
RL Proc. Natl. Acad. Sci. U.S.A. 111:7795-7800(2014).
RN [2] {ECO:0000313|EMBL:AMW06892.1, ECO:0000313|Proteomes:UP000076404}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AP64 {ECO:0000313|EMBL:AMW06892.1,
RC ECO:0000313|Proteomes:UP000076404};
RX PubMed=26636755; DOI=10.1111/1758-2229.12363;
RA Zeng Y., Baumbach J., Barbosa E.G., Azevedo V., Zhang C., Koblizek M.;
RT "Metagenomic evidence for the presence of phototrophic Gemmatimonadetes
RT bacteria in diverse environments.";
RL Environ. Microbiol. Rep. 8:139-149(2016).
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DR EMBL; CP011454; AMW06892.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A145Q4U5; -.
DR STRING; 1379270.GEMMAAP_14720; -.
DR KEGG; gph:GEMMAAP_14720; -.
DR eggNOG; COG0769; Bacteria.
DR Proteomes; UP000076404; Chromosome.
DR GO; GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.90.190.20; Mur ligase, C-terminal domain; 1.
DR Gene3D; 3.40.1190.10; Mur-like, catalytic domain; 1.
DR InterPro; IPR036565; Mur-like_cat_sf.
DR InterPro; IPR004101; Mur_ligase_C.
DR InterPro; IPR036615; Mur_ligase_C_dom_sf.
DR InterPro; IPR013221; Mur_ligase_cen.
DR PANTHER; PTHR23135:SF18; CYANOPHYCIN SYNTHETASE; 1.
DR PANTHER; PTHR23135; MUR LIGASE FAMILY MEMBER; 1.
DR Pfam; PF02875; Mur_ligase_C; 1.
DR Pfam; PF08245; Mur_ligase_M; 1.
DR SUPFAM; SSF53623; MurD-like peptide ligases, catalytic domain; 1.
DR SUPFAM; SSF53244; MurD-like peptide ligases, peptide-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000076404}.
FT DOMAIN 187..406
FT /note="Mur ligase central"
FT /evidence="ECO:0000259|Pfam:PF08245"
FT DOMAIN 432..494
FT /note="Mur ligase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02875"
SQ SEQUENCE 591 AA; 62955 MW; EB93E9F36526F3BA CRC64;
MLDSRRLTGA NWWSEQPGAV LEVRNAEAID RRALEQWPRE VRVLCDALGW PSGSPNAQQH
GVLSVCFLAA PLDGLMTATT VAEQAWVRAE LWVRSQDGDA DAAAWLLSST PTVHDALRTR
YDNERAPLVA ACAVVAEATK RGCSWQLDED MVSVGSGVYG LSWPLDRVPV AELVTWYTVA
DVPVVLVTGS NGKTTTTRLV TAMWRATGVT VGLSCSDGVF VHDDIGTREL AEGDYTGPGG
ARLVLRDRAV QAAVLETARG GMLRRGLATS RAHAAVITNI SADHFGEYGV ESLGDLARVK
ATVARILVPD ALLVLNADDE HLRALGAAME REHPNAVAWF SQDAAHPLVQ RGVQLHGYGA
VVCDGRLMLA EQGVWSDAGA LLHMPLTLNG LAPHNVENAL AASLAASVAG VPFAAVHRAL
HTFGADAGDN AGRLHRRVLG DVTVLVDYAH NPDGMRVLGA TAMAIPAARR LLVLGQAGNR
DDAQLVALAQ AAWASARYDR VFLKEMPEML RGREPGDVTR VLRAALLEAG APADVISEWP
SELDAVRAAL AWAQPGDLLV LPTHAQKEVV DALLNALEAQ GWYAGEPLAP L
//
