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Database: UniProt
Entry: A0A149VZV9_9PROT
LinkDB: A0A149VZV9_9PROT
Original site: A0A149VZV9_9PROT 
ID   A0A149VZV9_9PROT        Unreviewed;       529 AA.
AC   A0A149VZV9;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   05-JUL-2017, entry version 10.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724181};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377,
GN   ECO:0000313|EMBL:KXW58736.1};
GN   ORFNames=FEMY_07640 {ECO:0000313|EMBL:KXW58736.1};
OS   Ferrovum sp. Z-31.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Ferrovales; Ferrovaceae;
OC   Ferrovum.
OX   NCBI_TaxID=1789004 {ECO:0000313|EMBL:KXW58736.1, ECO:0000313|Proteomes:UP000075653};
RN   [1] {ECO:0000313|EMBL:KXW58736.1, ECO:0000313|Proteomes:UP000075653}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Z-31 {ECO:0000313|EMBL:KXW58736.1,
RC   ECO:0000313|Proteomes:UP000075653};
RA   Poehlein A., Ullrich S.R., Schloemann M., Muehling M., Daniel R.;
RT   "Genome sequence of the acidophilic iron oxidising Ferrovum strain Z-
RT   31.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00724167}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS00756131}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KXW58736.1}.
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DR   EMBL; LRRD01000011; KXW58736.1; -; Genomic_DNA.
DR   EnsemblBacteria; KXW58736; KXW58736; FEMY_07640.
DR   PATRIC; fig|1789004.3.peg.772; -.
DR   Proteomes; UP000075653; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-HAMAP.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-HAMAP.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF12; PTHR30050:SF12; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731922};
KW   Complete proteome {ECO:0000313|Proteomes:UP000075653};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS00756112};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00731887};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756124};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00731897};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075653}.
FT   DOMAIN      226    357       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      437    506       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     234    241       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   529 AA;  60567 MW;  F24B4AE949FCA100 CRC64;
     MSALSFGNRW LISTFHGIFL DFTNEPMITP QNIGLCQEKN IHIHPYLTVN NFVWTGVECR
     VNNRFHPTLL LVRYPHTVSI SPASERWQQT LLNLQAEYTE SQFNTWIKPL SEVIENNQVI
     LIAPNRFILQ WVKERYFQRI DELAREQGLD SVILQQKENS TILPENTSPP PDTHSQDTLA
     RTVLQPNPAE RSQLNRTFNF DNFVSGKANQ LARAAALQVA ENPGKAYNPL FVYGGVGLGK
     THLIQAIGNN ILERNPQAKV RYIHSEKYVS DVVRAYQHKS FDSFKQYYHT LDLLMIDDIQ
     FFGNKTRTQE EFFFAFNALV ESHRQIIITC DSFPKEISGM EPRLISRFGW GLTVAIEPPE
     LEMRVAILIS KAQKESIILE ESVAFFIAKH IRSNVRELEG ALKRVVAYAR FRNESISVIS
     AREALKDVLA LQHRQISIEN IQKTVADYYK IKVSDMFSKK RTRNLARPRQ MAMALAKEIT
     SLSLPDIGES FGGRDHTTVL HACRKIQELC GSDQTTQRDF EALNSILNG
//
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