ID   A0A150AN82_9BACT        Unreviewed;      1467 AA.
AC   A0A150AN82;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   RecName: Full=Acriflavine resistance protein B {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AVL50_06970 {ECO:0000313|EMBL:KXX71344.1};
OS   Flammeovirga sp. SJP92.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Flammeovirgaceae;
OC   Flammeovirga.
OX   NCBI_TaxID=1775430 {ECO:0000313|EMBL:KXX71344.1, ECO:0000313|Proteomes:UP000075267};
RN   [1] {ECO:0000313|EMBL:KXX71344.1, ECO:0000313|Proteomes:UP000075267}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SJP92 {ECO:0000313|EMBL:KXX71344.1,
RC   ECO:0000313|Proteomes:UP000075267};
RA   Shamseldin A., Moawad H., Abd El-Rahim W.M., Sadowsky M.J.;
RL   Submitted (DEC-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC       family. {ECO:0000256|ARBA:ARBA00007613}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXX71344.1}.
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DR   EMBL; LQAQ01000031; KXX71344.1; -; Genomic_DNA.
DR   STRING; 1775430.AVL50_06970; -.
DR   OrthoDB; 9758234at2; -.
DR   Proteomes; UP000075267; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   InterPro; IPR003423; OMP_efflux.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF18; CATION EFFLUX SYSTEM PROTEIN; 1.
DR   Pfam; PF00873; ACR_tran; 1.
DR   Pfam; PF02321; OEP; 2.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075267};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        336..355
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        432..454
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        466..491
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        527..545
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        860..876
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        882..902
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        959..975
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        981..1008
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   COILED          1053..1080
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1467 AA;  164939 MW;  ED831E9F309A5178 CRC64;
     MSIVKQALDH KQIILTITFL IVMYGIFSLE TMPRREDPKF NIREGLVVAF FPGASSVDVE
     KKVTAKIEDV LFSFEEVNKE KTYSNSREGV LYIVVELQDY VTQADIFWSK LQNRLNLLKL
     TELPSGVIGP IVQSDFGDTV ALLVSFQSKN RSSRENQGYV DELCDRLRGI TSLSKIKKMG
     SKKECYYINV DYRKLSQYKI YTPQILASLA GENLIVPSGR IEVNGINTQF ISTHQFSNQS
     DIENQIIAVG AQGETIRIKD IAEVERGFKE DDQYIRVNGT SSILISMEMQ NGFNIVDFGE
     EVENMVEEYQ SEIPSDVKID YVVNQPENVK ESINDFIREF FIAIISVIIV ILLLLPFRVA
     LIATLAIPVT VAFTFGILDG LGIQLQQVSL ASLIVVLGML VDDAIVIADN YVEKLEEDFD
     PYEAAWRSAD ELKIPVFTAG LTIAGAFFPL ITLSGAVGEF IHSLPLTVAI AINASYLVAM
     LLTPYLCYTF IKKKFEKKEG GKKSMLDYLQ LFFDHAIDLS FKYPKTLFLF STLSFIVGGS
     LYFLLKQKLF PAAERNQFVI EIRTKEGTAL SVTDSITLEI EKQINSNEKL VSYASFVGTS
     SPRFYYNYAP KFPQSNLSQL LINTISNEAT EEWVAELEEI LPDKFPEAVI DVKKMQQGTP
     YEAPIELRIK GKDYATIQKI AKDIRTILEK SPYSFNVRND HFENQLSIEV NTIKNVAQQL
     GISEATIMRQ LTVAYTGMSV GTLWEGNTAL PIIIQDKSVK HKNIEGLKNF YVTSMITGAS
     FPLMEVAEIS PAWMPSNIKH RNGVNTLTVE SQTKVDVLPS QVLNSIREEL NNYQMPHGYE
     LEIGGEDESQ RETFEEMNNV ILYCVFIIFL VILMQFKTLN QVSIVLAAIP LSVFGAFFGL
     LLSGYPFGFT AFVGLASLVG VSVRNSIILV DFANELVIKE NHTIKEAAIG AGKRRIRPIF
     LTTMAAAIGV TPMIISGSPM WAPLATVLAV GLVFSMFMTL LTIPVLYWKF GMTEELKKHI
     SKGAAVILFF FIFQPNDLLA QETIQLDQCV EIAKQNNQQL QLLQLEIQKK QKEVHKVTAN
     YLPTVILDGG LFWYYHTERT SDVSLKVNEL PLIGEVPPIP FGAEFTLAEN NTFLGVANVG
     VYQPISQIFK IKAGSEVKEI DYKIVQNKYY EAEQQIRSGV SKLYVGIAIE EAKVSTYQEQ
     IELIQKKLKD VEVGVDAGEL LDVYAIGLQA DLLDHQSKFQ QSKIDASKYR LQLNTILDFP
     QDSIWSVAEV TYDSIGVLEL LSTVSTDSSI ILDNYRVRES NLMIEKAEAG LSFHKNQHIP
     DITLTAQGFY FGNIPLIPQT NVLVGATLSW PILQWGKKSR DVEISKIQLQ QAKLQLDENK
     KEVTKDIIVV SEELKNAMVI LKTAQQALKF RDRELKIKKD AFDNGLLNYK DYSDCQEKNL
     ESRTLVLKAK ANVIVKEYEL RGLINSQ
//