ID A0A150IVJ3_9EURY Unreviewed; 385 AA.
AC A0A150IVJ3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA-directed RNA polymerase subunit Rpo1C {ECO:0000256|HAMAP-Rule:MF_00411};
DE EC=2.7.7.6 {ECO:0000256|HAMAP-Rule:MF_00411};
DE AltName: Full=DNA-directed RNA polymerase subunit A'' {ECO:0000256|HAMAP-Rule:MF_00411};
GN Name=rpoA2_2 {ECO:0000313|EMBL:KYC48885.1};
GN Synonyms=rpo1C {ECO:0000256|HAMAP-Rule:MF_00411}, rpoA2
GN {ECO:0000256|HAMAP-Rule:MF_00411};
GN ORFNames=AMQ74_01542 {ECO:0000313|EMBL:KYC48885.1};
OS Candidatus Methanofastidiosum methylthiophilus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Candidatus Methanofastidiosa;
OC Methanofastidiosum.
OX NCBI_TaxID=1705564 {ECO:0000313|EMBL:KYC48885.1, ECO:0000313|Proteomes:UP000075578};
RN [1] {ECO:0000313|EMBL:KYC48885.1, ECO:0000313|Proteomes:UP000075578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U1lsi0528_Bin089 {ECO:0000313|EMBL:KYC48885.1};
RX PubMed=26943620;
RA Nobu M.K., Narihiro T., Kuroda K., Mei R., Liu W.T.;
RT "Chasing the elusive Euryarchaeota class WSA2: genomes reveal a uniquely
RT fastidious methyl-reducing methanogen.";
RL ISME J. 0:0-0(2016).
CC -!- FUNCTION: DNA-dependent RNA polymerase (RNAP) catalyzes the
CC transcription of DNA into RNA using the four ribonucleoside
CC triphosphates as substrates. Forms part of the jaw domain.
CC {ECO:0000256|HAMAP-Rule:MF_00411}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.6; Evidence={ECO:0000256|HAMAP-Rule:MF_00411};
CC -!- SUBUNIT: Part of the RNA polymerase complex. {ECO:0000256|HAMAP-
CC Rule:MF_00411}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00411}.
CC -!- SIMILARITY: Belongs to the RNA polymerase beta' chain family.
CC {ECO:0000256|HAMAP-Rule:MF_00411}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYC48885.1}.
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DR EMBL; LNGD01000126; KYC48885.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A150IVJ3; -.
DR PATRIC; fig|1705564.3.peg.1634; -.
DR Proteomes; UP000075578; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003899; F:DNA-directed 5'-3' RNA polymerase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006351; P:DNA-templated transcription; IEA:UniProtKB-UniRule.
DR CDD; cd06528; RNAP_A; 1.
DR Gene3D; 1.10.150.390; -; 1.
DR HAMAP; MF_00411; RNApol_arch_Rpo1C; 1.
DR InterPro; IPR045867; DNA-dir_RpoC_beta_prime.
DR InterPro; IPR007081; RNA_pol_Rpb1_5.
DR InterPro; IPR012757; RPO1C.
DR NCBIfam; TIGR02389; RNA_pol_rpoA2; 1.
DR PANTHER; PTHR19376; DNA-DIRECTED RNA POLYMERASE; 1.
DR PANTHER; PTHR19376:SF69; DNA-DIRECTED RNA POLYMERASE SUBUNIT RPO1C; 1.
DR Pfam; PF04998; RNA_pol_Rpb1_5; 1.
DR SUPFAM; SSF64484; beta and beta-prime subunits of DNA dependent RNA-polymerase; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490, ECO:0000256|HAMAP-Rule:MF_00411};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00411};
KW DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW ECO:0000256|HAMAP-Rule:MF_00411};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695, ECO:0000256|HAMAP-
KW Rule:MF_00411};
KW Transcription {ECO:0000256|ARBA:ARBA00023163, ECO:0000256|HAMAP-
KW Rule:MF_00411};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|HAMAP-
KW Rule:MF_00411}.
FT DOMAIN 46..334
FT /note="RNA polymerase Rpb1"
FT /evidence="ECO:0000259|Pfam:PF04998"
SQ SEQUENCE 385 AA; 43291 MW; A5043DCB3034EC46 CRC64;
MVDTAYIDSQ LEKYQDKLTK FISDKLKDKL YMANDKYVLS EKEVDSIIED CIKAYETSLV
DPGEAVGTVA AQSLGEPGTQ MTLNTFHYAG VADINVTLGL PRIIEIVDAR KDPDTPVMRI
YLDEEIRDNR EKAEEIVKEI EGTTIESISK SMKIDVINMS IVVELDNYKM EKQGLTINDI
KEKLYKLKKV ENIEDEDNFL TLKAGDVSLM ELRKFFNRVR SHQLKGIKNV KRALIKKEGD
EYVIYTEGSN LGEAFKIPGV DITRSISNDI HEIQRVLGIE AARRSIVVEI KKTLEEQGLE
VDLRHIMLLA DLMTMEGEIK QIGRHGISGE KSSILARASF EVTTNHLMKA AKFGEIDPLS
GVTENVIIGQ PIPLGTGNVK LIMKK
//
