ID   A0A150IW57_9EURY        Unreviewed;       454 AA.
AC   A0A150IW57;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Modification methylase MjaII {ECO:0000313|EMBL:KYC49105.1};
DE            EC=2.1.1.113 {ECO:0000313|EMBL:KYC49105.1};
GN   Name=mjaIIM_2 {ECO:0000313|EMBL:KYC49105.1};
GN   ORFNames=AMQ74_01486 {ECO:0000313|EMBL:KYC49105.1};
OS   Candidatus Methanofastidiosum methylthiophilus.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Candidatus Methanofastidiosa;
OC   Methanofastidiosum.
OX   NCBI_TaxID=1705564 {ECO:0000313|EMBL:KYC49105.1, ECO:0000313|Proteomes:UP000075578};
RN   [1] {ECO:0000313|EMBL:KYC49105.1, ECO:0000313|Proteomes:UP000075578}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=U1lsi0528_Bin089 {ECO:0000313|EMBL:KYC49105.1};
RX   PubMed=26943620;
RA   Nobu M.K., Narihiro T., Kuroda K., Mei R., Liu W.T.;
RT   "Chasing the elusive Euryarchaeota class WSA2: genomes reveal a uniquely
RT   fastidious methyl-reducing methanogen.";
RL   ISME J. 0:0-0(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KYC49105.1}.
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DR   EMBL; LNGD01000115; KYC49105.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A150IW57; -.
DR   PATRIC; fig|1705564.3.peg.1569; -.
DR   Proteomes; UP000075578; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0015667; F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity; IEA:UniProtKB-EC.
DR   GO; GO:0044249; P:cellular biosynthetic process; IEA:UniProt.
DR   GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 2.
DR   InterPro; IPR002941; DNA_methylase_N4/N6.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   Pfam; PF01555; N6_N4_Mtase; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:KYC49105.1};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KYC49105.1}.
FT   DOMAIN          26..111
FT                   /note="DNA methylase N-4/N-6"
FT                   /evidence="ECO:0000259|Pfam:PF01555"
SQ   SEQUENCE   454 AA;  52950 MW;  F245E4D8E3DE7F35 CRC64;
     METMMKTVVN DVMFKTTKSR KEIINLFNTK KIDEDWSFAG YKPSDTGKWT HDYHRYPAKF
     IPQLVEKLID EYIPYKDAHI NDPFMGCGTT IVTAISRGFK ASGTDINKIA HLITKVKSTP
     IEPEYLNKKI EQLMSRLKVL NGTQITLFND KIEPLIPQKH IDRINYWFTE ENKNELGKIL
     RVIYDENDEV IRNFFLVAFS HILKNCSIWL QGSTKPTRDL EKKSVKPYDA LRRHLMKMRS
     GNDAFYEVVP DRIRKNINQY LNIEIGDARK QPVSDETVDL VVTSSPYVTS YEYADLHQLS
     TIWLDLADDL TEYKKEFIGT AYKKYENKRL RSSIAMDIVN KMSKKSKKMA KEIEAFFIDM
     EEVFDESFRI LKHGGRCCYV IGDTKLKGID ILNAEVFAES LQYSGFKFDR LLKREIPSKI
     LPQKRDEKTG RFANNHEANF EAYPIEYIVI GLKE
//