ID A0A150J9W3_9EURY Unreviewed; 685 AA.
AC A0A150J9W3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN Name=mcm_1 {ECO:0000313|EMBL:KYC53990.1};
GN ORFNames=AMQ74_00224 {ECO:0000313|EMBL:KYC53990.1};
OS Candidatus Methanofastidiosum methylthiophilus.
OC Archaea; Euryarchaeota; Stenosarchaea group; Candidatus Methanofastidiosa;
OC Methanofastidiosum.
OX NCBI_TaxID=1705564 {ECO:0000313|EMBL:KYC53990.1, ECO:0000313|Proteomes:UP000075578};
RN [1] {ECO:0000313|EMBL:KYC53990.1, ECO:0000313|Proteomes:UP000075578}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=U1lsi0528_Bin089 {ECO:0000313|EMBL:KYC53990.1};
RX PubMed=26943620;
RA Nobu M.K., Narihiro T., Kuroda K., Mei R., Liu W.T.;
RT "Chasing the elusive Euryarchaeota class WSA2: genomes reveal a uniquely
RT fastidious methyl-reducing methanogen.";
RL ISME J. 0:0-0(2016).
CC -!- SIMILARITY: Belongs to the MCM family. {ECO:0000256|ARBA:ARBA00008010,
CC ECO:0000256|RuleBase:RU004070}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYC53990.1}.
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DR EMBL; LNGD01000007; KYC53990.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A150J9W3; -.
DR PATRIC; fig|1705564.3.peg.225; -.
DR Proteomes; UP000075578; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR Gene3D; 2.20.28.10; -; 1.
DR Gene3D; 3.30.1640.10; mini-chromosome maintenance (MCM) complex, chain A, domain 1; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR031327; MCM.
DR InterPro; IPR001208; MCM_dom.
DR InterPro; IPR041562; MCM_lid.
DR InterPro; IPR027925; MCM_N.
DR InterPro; IPR033762; MCM_OB.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR11630; DNA REPLICATION LICENSING FACTOR MCM FAMILY MEMBER; 1.
DR PANTHER; PTHR11630:SF43; DNA REPLICATION LICENSING FACTOR MCM6; 1.
DR Pfam; PF00493; MCM; 1.
DR Pfam; PF17855; MCM_lid; 1.
DR Pfam; PF14551; MCM_N; 1.
DR Pfam; PF17207; MCM_OB; 1.
DR PRINTS; PR01657; MCMFAMILY.
DR SMART; SM00350; MCM; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50051; MCM_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU004070};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004070};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KYC53990.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004070}.
FT DOMAIN 282..488
FT /note="MCM"
FT /evidence="ECO:0000259|PROSITE:PS50051"
SQ SEQUENCE 685 AA; 77100 MW; D4946E4F84375128 CRC64;
MKLSYEEIED KFKELFESYP DVSEPKYKKI IDKMKLEGKL SIYINFDDII DFNFDLSEQL
LSSPEEVFPA AIDALKEVYG AEQGKRLAVR ITNLPITERI DIKDIRAVHI NKLIQVEGVV
RRTTEVKPEI IEAVFECERC GDFITIYQDS IIFKPPITCS NPSCGRNGPF KLMKMHSTFV
DWQSIKIQEK PEKLRGGQLP RSLDCTIKEE IVDTAQPGNV VTIVGILKTL QEGAGKTGGK
KTTFSKFLEV NSIEIKEKDI QDLELSEEDE EKIRELASDP KICENITNSI APSIYGNQHV
KYAVALQLFS SEARLLQDGT RIRGDSHILL VGDPGVAKSQ ILKYMNMVAP RSIYTSGKGT
SAAGLTAAVI RDETSGTFAL EAGALVIADN GIACIDEIDK MSNDDRSSIH EAMEQQTVSI
AKAGIIATLN ARASILAAAN PKRGRFDSYK PLGEQIDLLP TLLSRFDLIF ILTDKPKESE
DKKIAEHILK LHSNEEDNIT PPIETETIRK YAIYSKKTIQ EISLTDEAKN RLLEFYVSIR
KKGEEKNTPI PITARQLESL IRLSEARARM RLSDKVMVED VEEIIQLYMK SIEDIGKDPE
TGEIDIDMIM TGRPKSQRDK ITIIMEIISN LDKKSNNEGA LISELYEEAR AENISDSFTR
KIIDELKQKG DVYEPRPDRL KLTLM
//
