ID   A0A151BM25_9ARCH        Unreviewed;      1016 AA.
AC   A0A151BM25;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Glycoside hydrolase family 38 central domain-containing protein {ECO:0000259|SMART:SM00872};
GN   ORFNames=AYL32_007890 {ECO:0000313|EMBL:KYH40971.1};
OS   Candidatus Bathyarchaeota archaeon B26-2.
OC   Archaea; Candidatus Bathyarchaeota.
OX   NCBI_TaxID=1779371 {ECO:0000313|EMBL:KYH40971.1, ECO:0000313|Proteomes:UP000075437};
RN   [1] {ECO:0000313|EMBL:KYH40971.1, ECO:0000313|Proteomes:UP000075437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B26-2 {ECO:0000313|EMBL:KYH40971.1};
RA   He Y., Li M., Perumal V., Feng X., Fang J., Xie J., Sievert S., Wang F.;
RT   "Evidence for homoacetogenesis among multiple lineages of the archaeal
RT   phylum Bathyarchaeota widespread in marine sediments.";
RL   Submitted (MAR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC       {ECO:0000256|ARBA:ARBA00009792}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KYH40971.1}.
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DR   EMBL; LUCE01000019; KYH40971.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A151BM25; -.
DR   STRING; 1779371.AYL32_007890; -.
DR   Proteomes; UP000075437; Unassembled WGS sequence.
DR   GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR   CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR   Gene3D; 2.60.40.2220; -; 1.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR   Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR041147; GH38_C.
DR   InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR   InterPro; IPR011682; Glyco_hydro_38_C.
DR   InterPro; IPR015341; Glyco_hydro_38_cen.
DR   InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR   InterPro; IPR000602; Glyco_hydro_38_N.
DR   InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR   InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR   PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR   PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR   Pfam; PF09261; Alpha-mann_mid; 1.
DR   Pfam; PF17677; Glyco_hydro38C2; 1.
DR   Pfam; PF07748; Glyco_hydro_38C; 1.
DR   Pfam; PF01074; Glyco_hydro_38N; 1.
DR   SMART; SM00872; Alpha-mann_mid; 1.
DR   SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR   SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR   SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00023295};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723}.
FT   DOMAIN          488..558
FT                   /note="Glycoside hydrolase family 38 central"
FT                   /evidence="ECO:0000259|SMART:SM00872"
SQ   SEQUENCE   1016 AA;  115572 MW;  1AA3F48DC098431F CRC64;
     MKVGDKLSLL LTKLEEKHNE LTKYREALRW KILRGNPEDA HKADFDDSSW EEAALPLTLD
     ATEGDVWLRC EFLVPQKVAE IETAGSTVKL TSSPILGRAE IFVNSRLALK SEYWTELRVP
     IVLGERVKPR SRYVVAVHIV PVESPVPVQV TVPRFKVTLS KVEEVAFELD SFIQELRFAH
     FLDEATARQI VEGFNIQALK EGYAFILDEV EKARAALSTL SERAKEFKVH LVAHAHIDMN
     WLWPWDDTVE TVRETFTTMV KLMDKYPSFH FSQSQAVTYN VVEENFPKLF EAIREYVAKG
     NWDVTAAMWV EADLNMAGTE ALVRQFLYGR RYVKESFGVE PKVCWEPDTF GHVWTLPQIL
     RKSGVRYYYF MRCGKDHPLF WWMSPDGSKV LAFTSVYNNT ITPKKIVEAA IEMYERYGLK
     TSMFVYGVGD HGGGATEEDI EAAIKIAKKP ALPSAVFSTT HGFFEEVEGQ IREIDVPLVN
     DELNFIFDGC YTTHSDIKRY NRLCERLLVD AEKLCAVSGK YPREALKKAW LNTLFNQFHD
     ILDGSGTHGA YDYPKKLAEE TIEFTRETLE RSLKEISEKI GFSGLGIPVV VFNTLPWKRR
     DIVRVKVSPS ILPGNPVAVS GEERSPVQVS GEEIMFLAKV PSMGYRTYYI VEGKKSEEAP
     AGSGEALENE YLRVEVDKAS GTIRSLYDKT SGRFVFKRDR YPNTRPVLSN LLQVLYEVPH
     GMSAWIIGAI SRTENLIKGA DVGLVENGPV RAMIRVVHKY RRSTITQEIS VYKGLPRVDF
     HTTIDWRETA DGKSDFPMLK VSFTPILGDS KATFEIPFGY IERVADGTEV PALRWVDLSD
     GNYGLSILND SKYGFDVQGN TVRMTLIRTS YSPDPRPDQG THHVLYSIYP HKGDWREAQT
     FRRGYEINHP LEAVVFKELP TEAGSEPEEA SFIEVDPENV VLSCLKLAED SNDYIIRVYD
     ATGEGADAEV RFKSDLVEAF EVDMMEKPLR NLRVNGRRIL FRLHPFEIKT IRVSMA
//