ID A0A151FAW7_9EURY Unreviewed; 365 AA.
AC A0A151FAW7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=AYK18_08685 {ECO:0000313|EMBL:KYK37986.1};
OS Theionarchaea archaeon DG-70.
OC Archaea; Euryarchaeota; Theionarchaea.
OX NCBI_TaxID=1803813 {ECO:0000313|EMBL:KYK37986.1, ECO:0000313|Proteomes:UP000075311};
RN [1] {ECO:0000313|Proteomes:UP000075311}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Baker B.J., Lazar C.S., Teske A.P., Dick G.J.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYK37986.1}.
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DR EMBL; LSSB01000044; KYK37986.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151FAW7; -.
DR Proteomes; UP000075311; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR017200; PqqE-like.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF7; PQQA PEPTIDE CYCLASE; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR Pfam; PF13186; SPASM; 1.
DR PIRSF; PIRSF037420; PQQ_syn_pqqE; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 16..229
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 365 AA; 40825 MW; 4CAEE9DADF1634D2 CRC64;
MKILSSTEDY TQFFSGDPLL SFSLRVTIKC NLRCEHCYAN SGTSHGKELE LGEIERLLEE
AREIGCCGVF YTGGEPFVRR DMVDILKETS TRGIPIYLSS NGTLIDREKL EQLKGIPFRL
FQISIDGPSP EVHDKIRNVE GTFQRATNVI KAASGILGKN VALSSVLMKS NYQVIPDVMR
LAADLGADTF ALMLLLVTGR AKEEIDPTPA EKVSTFEKIF EKYRELNGKI KFASNTTIPL
ALIPEDIRNP ENPPFCLCSF PLTMGIDEMG NVFPCDGFMN FEEYKAGNIR ENGLTHIWEN
SKMLRKLKTM ELTELKGICS KCKYLDVCGG GCRAAAHIRY GDIRMPDPVC QDLFDAGLFP
EECLR
//
