ID   A0A151M0M1_ALLMI        Unreviewed;       244 AA.
AC   A0A151M0M1;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=Rho-related GTP-binding protein RhoE {ECO:0000256|ARBA:ARBA00018498};
DE   AltName: Full=Rho family GTPase 3 {ECO:0000256|ARBA:ARBA00031352};
DE   AltName: Full=Rnd3 {ECO:0000256|ARBA:ARBA00032042};
GN   Name=RND3 {ECO:0000313|EMBL:KYO18020.1};
GN   ORFNames=Y1Q_0011623 {ECO:0000313|EMBL:KYO18020.1};
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO18020.1};
RN   [1] {ECO:0000313|EMBL:KYO18020.1, ECO:0000313|Proteomes:UP000050525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO18020.1};
RX   PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA   St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA   Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA   Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA   Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA   Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA   McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA   Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA   Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA   Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA   Ray D.A.;
RT   "Sequencing three crocodilian genomes to illuminate the evolution of
RT   archosaurs and amniotes.";
RL   Genome Biol. 13:415-415(2012).
CC   -!- FUNCTION: Binds GTP but lacks intrinsic GTPase activity and is
CC       resistant to Rho-specific GTPase-activating proteins.
CC       {ECO:0000256|ARBA:ARBA00003614}.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rho family.
CC       {ECO:0000256|ARBA:ARBA00010142}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KYO18020.1}.
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DR   EMBL; AKHW03006853; KYO18020.1; -; Genomic_DNA.
DR   RefSeq; XP_006268560.1; XM_006268498.3.
DR   AlphaFoldDB; A0A151M0M1; -.
DR   STRING; 8496.A0A151M0M1; -.
DR   GeneID; 102574370; -.
DR   KEGG; amj:102574370; -.
DR   CTD; 390; -.
DR   eggNOG; KOG0393; Eukaryota.
DR   OrthoDB; 20499at2759; -.
DR   PhylomeDB; A0A151M0M1; -.
DR   Proteomes; UP000050525; Unassembled WGS sequence.
DR   GO; GO:0005525; F:GTP binding; IEA:InterPro.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   CDD; cd04172; Rnd3_RhoE_Rho8; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR041843; RhoE.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   InterPro; IPR003578; Small_GTPase_Rho.
DR   NCBIfam; TIGR00231; small_GTP; 1.
DR   PANTHER; PTHR24072; RHO FAMILY GTPASE; 1.
DR   PANTHER; PTHR24072:SF24; RHO-RELATED GTP-BINDING PROTEIN RHOE; 1.
DR   Pfam; PF00071; Ras; 1.
DR   PRINTS; PR00449; RASTRNSFRMNG.
DR   SMART; SM00175; RAB; 1.
DR   SMART; SM00173; RAS; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51419; RAB; 1.
DR   PROSITE; PS51421; RAS; 1.
DR   PROSITE; PS51420; RHO; 1.
PE   3: Inferred from homology;
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Lipoprotein {ECO:0000256|ARBA:ARBA00023288};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050525}.
SQ   SEQUENCE   244 AA;  27352 MW;  D410AF93066AA32E CRC64;
     MKERRASQKL SSKAVMDPNQ NVKCKIVVVG DSQCGKTALL HVFAKDCFPE NYVPTVFENY
     TASFEIDTQR IELSLWDTSG SPYYDNVRPL SYPDSDAVLI CFDISRPETL DSVLKKWKGE
     IQEFCPNTKM LLVGCKSDLR TDVSTLVELS NHRQTPVSYD QGANMAKQIG AATYIECSAL
     QSENSVRDIF HVATLACVNK TNKNIKRNKS QRATKRISHM PGRPELSTVA TDLRKDKAKS
     CTVM
//