GenomeNet

Database: UniProt
Entry: A0A151M2U5_ALLMI
LinkDB: A0A151M2U5_ALLMI
Original site: A0A151M2U5_ALLMI 
ID   A0A151M2U5_ALLMI        Unreviewed;      5012 AA.
AC   A0A151M2U5;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   22-NOV-2017, entry version 10.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KYO18847.1};
GN   ORFNames=Y1Q_0009256 {ECO:0000313|EMBL:KYO18847.1};
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO18847.1};
RN   [1] {ECO:0000313|EMBL:KYO18847.1, ECO:0000313|Proteomes:UP000050525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO18847.1};
RX   PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA   St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y.,
RA   Gongora J., Dalzell P., Moran C., Bed'hom B., Abzhanov A.,
RA   Burgess S.C., Cooksey A.M., Castoe T.A., Crawford N.G., Densmore L.D.,
RA   Drew J.C., Edwards S.V., Faircloth B.C., Fujita M.K., Greenwold M.J.,
RA   Hoffmann F.G., Howard J.M., Iguchi T., Janes D.E., Khan S.Y.,
RA   Kohno S., de Koning A.J., Lance S.L., McCarthy F.M., McCormack J.E.,
RA   Merchant M.E., Peterson D.G., Pollock D.D., Pourmand N., Raney B.J.,
RA   Roessler K.A., Sanford J.R., Sawyer R.H., Schmidt C.J., Triplett E.W.,
RA   Tuberville T.D., Venegas-Anaya M., Howard J.T., Jarvis E.D.,
RA   Guillette L.J.Jr., Glenn T.C., Green R.E., Ray D.A.;
RT   "Sequencing three crocodilian genomes to illuminate the evolution of
RT   archosaurs and amniotes.";
RL   Genome Biol. 13:415-415(2012).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KYO18847.1}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AKHW03006780; KYO18847.1; -; Genomic_DNA.
DR   Proteomes; UP000050525; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 2.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 5.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000050525};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4323   4341       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4545   4565       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4619   4638       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4755   4776       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4813   4834       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4889   4912       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      144    199       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      206    251       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      259    314       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      320    377       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      385    442       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      645    843       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1091   1288       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1422   1627       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4066   4101       EF-hand. {ECO:0000259|PROSITE:PS50222}.
SQ   SEQUENCE   5012 AA;  569930 MW;  40E186A3CA9C327A CRC64;
     MAARLHADQG SARDSGSRWI PPPCLVFPVF LLGQEQLRLD PIWHVEQAWL GPDQVVQWEA
     NLDDEVVLQC TATVHKEQQK LCLAAEGFGN RLCFLESTSN SKNVPPDLSI CTFVLEQSLS
     VRALQEMLAN TEEKAEGTAQ GGGHRTLLYG HAILLRHSYS GMYLCCLSTS RSSMDKLAFD
     VGLQEDTTGE ACWWTIHPAS KQRSEGEKVR VGDDLILVSI SSERYLHLSY GNGSLHVDAA
     FQQTLWSVAP ISSGSEVAQG YLIGGDVLRL LHGHMDECLT VPSGEHGEEL RRTVHYEGGA
     VSIHARSLWR LETLRVAWSG SHIRWGQPFR LRHITTGKYL SLLDDKSLLL TDKEQADVKS
     TAFCFRSSKE KLDVGIRKEV DGMGAPEIKY GDSVCYIQHI DTGLWLTYQS VDAKSVRMGS
     VQRKAIMHHE GHMDDGLTLS RSQHEESRTA RVIRSTVFLF NRFIRGLDAL SKKAKSSTVD
     LPIESVSLSL QDLIGYFHPP DEHLEHEDKQ NRLRALKNRQ NLFQEEGMIN LVLECIDRLH
     VYSSAAHFAD VAGKEAGETW KSILNSLYEL LAALIRGNRK NCAQFSGSLD WLISRLERLE
     ASSGILEVLH CVLVESPEAL NIIKEGHIKS IICLLDKHGR NHKVLDVLCS LCVCHGVAVR
     SNQHLICDNL LPGRDLLLQT RLVNHVSSMR PNIFLGISEG SAQYRKWYYE LMVDHVEPFV
     TAEATHLRVG WASTEGYSPY PGGGAEWGGN GVGDDLYSYG FDGLHLWSGC VARTVNSPNQ
     HLLKTDDVVS CCLDLSAPSI SFRINGQPVQ GMFENFNIDG LFFPVVSFSA GIKVRFLLGG
     RHGEFKFLPP PGYAPCFEAV LPKEKLKVEQ SREYKQDRNG TKDLLGPTIS LSQAAFTPIP
     VDTSQIVLPP HLERIREKLA ENIHELWVMN KIELGWQYGP VRDDNKRQHP CLVEFSKLPE
     QERNYNLQMS LETLKTLLAL GCHVGITDEH AEEKVKKVKL PKNYQLSSGY KPTPMDLSSI
     KLTPSQEAMV DKLAENAHNV WARDRIRQGW TYGIQQSQPA SQQREHKLTN KPCSQNCADI
     NDDTDHKQDV KNRRNPRLVP YALLDDRTKK SNKDSLREAV RTLLGYGYNL EAPDQDHATR
     SDVYSGIMEK FRIFRTEKTY AVKSGKWYFE FEAVTAGDMR VGWTRPGCLP DQELGADEQA
     FVFDGFKAQR WHQGNEHFGR SWLAGDVVGC MVDMNEHTMM FTLNGEILLD DSGSELAFKD
     FEVGDGFIPV CSLGSSQVGR MNFGKDVSTL KYFTICGLQE GYEPFAVNTN RDITMWLSKR
     LPQFLPVPPN HEHIEVMRID GTIDSCPCLK VTKKSFGSNS KTDVMFFRLS MPIECAEVFS
     KTPAGGLPGS GLFGPKNDLE DYDADSDFEV LMKTAHGHLV PDRVEREKEA AKPEFNNHKD
     YTQEKPSRLK QRFMLRRTKP DYSTSHSARL TEDVLADDRD DYDYLMQTST YYYSVRIFPG
     QEPANVWVGW ITSDFHQYDT TFDLDRVRTV TVTLGDEKGK VHESIKRSNC YMVCAGESMS
     PGQGRNNNGL EIGCLVDAAS GLVTFTANGK ELSTYYQVEP STKLFPAVFA QATSPNVFQF
     ELGRIKNVMP LSAGLFKSEH KNPVPQCPPR LHVQFLTHVL WSRVPNHFLK VDVSRVSERQ
     GWMIQCLDPL QFMALHVPEE NRSIDILELT EQEELLKFHY HALRLYSAVC ALGNNRVAHA
     MCSHVDESQL LYAIENKYMP GLLRTGYYDL LIDIHLNTYA TARLMMNNEF IVPMTDETKS
     ITLFPDENKK HGLPGIGLST SLRPRMQFSS PSFVSISSEC YQFSPEFPLE ILKAKTIEML
     TEAVQEGSLH VRDPVGGSTE FLFVPLIKLF YTLLIMGVFH NGDLKHILQL IEPRVFKEDT
     SQEDENEMPE KELTTKELKP EGGEEEARGE QVPKEGLLQM KLPEPVKLQM CHLLQYLCDC
     QIRHRIEAIV AFSDDFVAKL QENQRFRYNE VMQALNMSAA LTARKTKEFR SPPQEQINML
     LNFKDDKSDC PCPEEIRDQL LDFHEDLMTH CGIELDEDGA LDGSSDLTIR GRLLYLVEKM
     TYLKKKQTEK PTDNHSKKPS TLQQLISDTM VRWAQESVIE DPELVRAMFV LLHRQYDGIG
     GLVRTLPKTY TINSVSVEDT INLLASLGQI RSLLSVRMGK EEEKLMIRGL GDIMNNKVFY
     QHPNLMRALG MHETVMEVMV NVLGGGESKE ITFPKMVANC CRFLCYFCRI SRQNQKAMFD
     HLSYLLENSS VGLASPSMRG STPLDVAAAS VMDNNELALA LREPDLEKVV RYLAGCGLQS
     CPLLISKGYP DIGWNPVEGE RYLDFLRFAV FCNGESVEEN ANVVVRLLIR RPECFGPALR
     GEGGNGLLAA MEEAIKISED PTRDGPSPSN GSCKTLEMEE QEDDTIHVGN AIMTFYAALI
     DLLGRCAPEM HLIHAGKGEA IRIRSILRSL IPLEDLVGVI SIPFHMPTIA KDGTVVEPDM
     SAGFCPDHKA AMVLFLDRVY GIEDQDFLLH LLEVGFLPDL RAAASLDTAA LSATDMALAL
     NRYLCTAVLP LLTRCAPLFA GTEHHASLID SLLHTVYRLS KGCSLTKAQR DSIEECLLSI
     CGQLRPSMMQ HLLRRLVFDV PLLNEHAKMP LKLLTNHYER CWKYYCLPGG WGNFGAASEE
     ELHLSRKLFW GIFDALSQKK YEQELFKLAL PCLSAVAGAL PPDYMESNYV SMMEKQSSMD
     SDGNFNPQPV DTSNSTIPEK LEYFINKYAE HSHDKWSMEK FANGWIYGEM YSESAKVQPL
     MKQYKLLSEK EKEIYRWPIK ESLKTMLAWG WRIERTREGD TMALYNRTRR ISQTSQVSVD
     TAHGYSPRAI DMSNVTLSRD LHAMAEMMAE NYHNIWAKKK KMELEAKVGG GNHPLLVPYD
     TLTAKEKAKD REKAQDILKF LQINGYIVSR GLKDLELDTP SIEKRFAYSF LQQLIRYVDE
     AHQYILEFDG GSRGKGEHFP YEQEIKFFAK VVLPLIDQYF KNHRLYFLSA ASRPLSTGGH
     ASNKEKEMVT SLFCKLGVLV RHRISLFGND ATSIVNCLHI LGQTLDARTV MKTGLESVKM
     ALRAFLDNAA EDLEKTMENL KQGQFTHTRN QPKGVTQIIN YTTVALLPVL SSLFEHIGQH
     QFGEDLILED VQVSCYRILA SLYALGTSKS IYVERQRSAL GECLAAFAGA FPVAFLETHL
     NKHNMYSIYN TKCARDRAAL DLPTSVDEVC PNIPSLEKLM EEIVELAESG IRYTQMPHIM
     EVILPMLCSY MSHWWEHGPE NNPEKAEMCC TGLTSEHMNT LLGNILKIIY NNLGIDEGAW
     MKRLAVFSQP IISKAKPQLL KTHFLPLMDK LKKKAAMVIS DEEHLRAEGR GDMSEAELLI
     LDEFTTLARD LYAFYPLLIR FVDYNRAKWL KEPNPEAEEL FRMVADVFIY WSKSHNFKRE
     EQNFVVQNEI NNMSFLITDT KSKMSKAAVS DQERKKMKRK GDRYSTQTSL IVAALKRLLP
     IGLNICAPGD QELIALAKTR FSMKDTEDEV RDIIRSNLHL QGKLEDPAIR WQMALYKDLP
     NRTENTSDPE KTVERVLDIA NVLFHLEQVE HPQRSKKAVW HKLLSKQRKR AVVACFRMAP
     LYNLPRHRAV NLFLQGYEKS WIETEEHYFE DKLIEDLARP GEEPPEEEES IKRVDPLHQL
     ILLFSRTALT EKCKLEEDFL YMAYADIMAK VTGSQRSKEK EMEKQKLLYQ QARLHDRGAA
     EMVLQTISAS KGEMGPMVAA TLKLGIAILN GGNSTVQQKM LDYLKDKKDV GFFQSLAGLM
     QFCSVLDLNA FERQNKAEGL GMVTEEGSGE KVMQDDEFTC DLFRFLQLLC EGHNSDFQNY
     LRTQTGNNTT VNIIISTVDY LLRVQESISD FYWYYSGKDV IDEQGQRNFS KAIQVAKQVF
     NTLTEYIQGP CTGNQQSLAH SRLWDAVVGF LHVFAHMQMK LSQDSSQIEL LKELMDLQKD
     MVVMLLSMLE GNVVNGTIGK QMVDMLVESS NNVEMILKFF DMFLKLKDLT SSDAFKEYDP
     DGKGVISKRD FQKAMESHKH YTQSETEFLL SCAEPDENET LDYEEFVKRF HEPAKDIGFN
     VAVLLTNLSE HMPHDTRLQT FLELAESVLN YFQPFLGRIE IMGSAKRIER VYFEISESSR
     TQWEKPQVKE SKRQFIFDVV NEGGEKEKME LFVNFCEDTI FEMQLAAQIS ESDLSERSAN
     KEESEKDKLE EQDPRMGFFS LVTVKSALVA LKYNIMTLMK MLSVKSLKKQ MKKMKKMTMK
     DMVTAFFSSY WSILMGLLHF TSSVFRGFFR IMYSLLLGGS LVEGAKKIKV AELLANMPDP
     TQDEVRGEGE EGERKPTETA LPAEDLTDLT ALSDDGDLLS DIFGLDLKRE GGQYKLIPHN
     PNAGLSDLLS TPSLLPLPEV QEKVQEQKVK EDEKDEKEES KSEPEKAEGE DGEKEEKTKD
     EKGKQKLRQL HTHRYGEPEV QESAFWKKII AYQQKLLNYF ARNFYNMRML ALFVAFAINF
     ILLFYKVSTS SVTEEKEVHV VHAGENSKLN SLESGSHRII TVHYVLEESS GYMEPTLRIL
     AILHTVISFF CIIGYYCLKV PLVIFKREKE VARKLEFDGL YITEQPSEDD IKGQWDRLVI
     NTQSFPNNYW DKFVKRKVMD KYGEFYGRDR ISELLGMDKA ALDFSDAREK KKPKKDSSLS
     AVLNSIDVKY QMWKLGVVFT DNSFLYLAWY MTMSVLGHYN NFFFAAHLLD IAMGFKTLRT
     ILSSVTHNGK QLVLTVGLLA VVVYLYTVVA FNFFRKFYNK SEDGDMPDMK CDDMLTCYMF
     HMYVGVRAGG GIGDEIEDPA GDEYEIYRII FDITFFFFVI VILLAIIQGL IIDAFGELRD
     QQEQVKEDME TKCFICGIGN DYFDTVPHGF ETHTLQEHNL ANYLFFLMYL INKDETEHTG
     QESYVWKMYQ ERCWEFFPAG DCFRKQYEDQ LN
//
DBGET integrated database retrieval system