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Database: UniProt
Entry: A0A151M2X0_ALLMI
LinkDB: A0A151M2X0_ALLMI
Original site: A0A151M2X0_ALLMI 
ID   A0A151M2X0_ALLMI        Unreviewed;      4980 AA.
AC   A0A151M2X0;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   20-DEC-2017, entry version 11.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KYO18848.1};
GN   ORFNames=Y1Q_0009256 {ECO:0000313|EMBL:KYO18848.1};
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO18848.1};
RN   [1] {ECO:0000313|EMBL:KYO18848.1, ECO:0000313|Proteomes:UP000050525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO18848.1};
RX   PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA   St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y.,
RA   Gongora J., Dalzell P., Moran C., Bed'hom B., Abzhanov A.,
RA   Burgess S.C., Cooksey A.M., Castoe T.A., Crawford N.G., Densmore L.D.,
RA   Drew J.C., Edwards S.V., Faircloth B.C., Fujita M.K., Greenwold M.J.,
RA   Hoffmann F.G., Howard J.M., Iguchi T., Janes D.E., Khan S.Y.,
RA   Kohno S., de Koning A.J., Lance S.L., McCarthy F.M., McCormack J.E.,
RA   Merchant M.E., Peterson D.G., Pollock D.D., Pourmand N., Raney B.J.,
RA   Roessler K.A., Sanford J.R., Sawyer R.H., Schmidt C.J., Triplett E.W.,
RA   Tuberville T.D., Venegas-Anaya M., Howard J.T., Jarvis E.D.,
RA   Guillette L.J.Jr., Glenn T.C., Green R.E., Ray D.A.;
RT   "Sequencing three crocodilian genomes to illuminate the evolution of
RT   archosaurs and amniotes.";
RL   Genome Biol. 13:415-415(2012).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00448}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KYO18848.1}.
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DR   EMBL; AKHW03006780; KYO18848.1; -; Genomic_DNA.
DR   Proteomes; UP000050525; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   Gene3D; 1.25.10.30; -; 2.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR035910; IP3R_RIH_dom_sf.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000050525};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4291   4309       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4513   4533       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4587   4606       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4723   4744       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4781   4802       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4857   4880       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      144    199       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      206    251       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      259    314       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      320    377       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      385    442       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      645    843       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1059   1256       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1390   1595       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4034   4069       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   COILED      506    526       {ECO:0000256|SAM:Coils}.
FT   COILED     3091   3111       {ECO:0000256|SAM:Coils}.
FT   COILED     4220   4240       {ECO:0000256|SAM:Coils}.
FT   COILED     4431   4451       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   4980 AA;  566310 MW;  EF1A1FB8D090CF51 CRC64;
     MAARLHADQG SARDSGSRWI PPPCLVFPVF LLGQEQLRLD PIWHVEQAWL GPDQVVQWEA
     NLDDEVVLQC TATVHKEQQK LCLAAEGFGN RLCFLESTSN SKNVPPDLSI CTFVLEQSLS
     VRALQEMLAN TEEKAEGTAQ GGGHRTLLYG HAILLRHSYS GMYLCCLSTS RSSMDKLAFD
     VGLQEDTTGE ACWWTIHPAS KQRSEGEKVR VGDDLILVSI SSERYLHLSY GNGSLHVDAA
     FQQTLWSVAP ISSGSEVAQG YLIGGDVLRL LHGHMDECLT VPSGEHGEEL RRTVHYEGGA
     VSIHARSLWR LETLRVAWSG SHIRWGQPFR LRHITTGKYL SLLDDKSLLL TDKEQADVKS
     TAFCFRSSKE KLDVGIRKEV DGMGAPEIKY GDSVCYIQHI DTGLWLTYQS VDAKSVRMGS
     VQRKAIMHHE GHMDDGLTLS RSQHEESRTA RVIRSTVFLF NRFIRGLDAL SKKAKSSTVD
     LPIESVSLSL QDLIGYFHPP DEHLEHEDKQ NRLRALKNRQ NLFQEEGMIN LVLECIDRLH
     VYSSAAHFAD VAGKEAGETW KSILNSLYEL LAALIRGNRK NCAQFSGSLD WLISRLERLE
     ASSGILEVLH CVLVESPEAL NIIKEGHIKS IICLLDKHGR NHKVLDVLCS LCVCHGVAVR
     SNQHLICDNL LPGRDLLLQT RLVNHVSSMR PNIFLGISEG SAQYRKWYYE LMVDHVEPFV
     TAEATHLRVG WASTEGYSPY PGGGAEWGGN GVGDDLYSYG FDGLHLWSGC VARTVNSPNQ
     HLLKTDDVVS CCLDLSAPSI SFRINGQPVQ GMFENFNIDG LFFPVVSFSA GIKVRFLLGG
     RHGEFKFLPP PGYAPCFEAV LPKEKLKVEQ SREYKQDRNG TKDLLGPTIS LSQAAFTPIP
     VDTSQIVLPP HLERIREKLA ENIHELWVMN KIELGWQYGP VRDDNKRQHP CLVEFSKLPE
     QERNYNLQMS LETLKTLLAL GCHVGITDEH AEEKVKKVKL PKNYQLSSGY KPTPMDLSSI
     KLTPSQEAMV DKLAENAHNV WARDRIRQGW TYGIQQDVKN RRNPRLVPYA LLDDRTKKSN
     KDSLREAVRT LLGYGYNLEA PDQDHATRSD VYSGIMEKFR IFRTEKTYAV KSGKWYFEFE
     AVTAGDMRVG WTRPGCLPDQ ELGADEQAFV FDGFKAQRWH QGNEHFGRSW LAGDVVGCMV
     DMNEHTMMFT LNGEILLDDS GSELAFKDFE VGDGFIPVCS LGSSQVGRMN FGKDVSTLKY
     FTICGLQEGY EPFAVNTNRD ITMWLSKRLP QFLPVPPNHE HIEVMRIDGT IDSCPCLKVT
     KKSFGSNSKT DVMFFRLSMP IECAEVFSKT PAGGLPGSGL FGPKNDLEDY DADSDFEVLM
     KTAHGHLVPD RVEREKEAAK PEFNNHKDYT QEKPSRLKQR FMLRRTKPDY STSHSARLTE
     DVLADDRDDY DYLMQTSTYY YSVRIFPGQE PANVWVGWIT SDFHQYDTTF DLDRVRTVTV
     TLGDEKGKVH ESIKRSNCYM VCAGESMSPG QGRNNNGLEI GCLVDAASGL VTFTANGKEL
     STYYQVEPST KLFPAVFAQA TSPNVFQFEL GRIKNVMPLS AGLFKSEHKN PVPQCPPRLH
     VQFLTHVLWS RVPNHFLKVD VSRVSERQGW MIQCLDPLQF MALHVPEENR SIDILELTEQ
     EELLKFHYHA LRLYSAVCAL GNNRVAHAMC SHVDESQLLY AIENKYMPGL LRTGYYDLLI
     DIHLNTYATA RLMMNNEFIV PMTDETKSIT LFPDENKKHG LPGIGLSTSL RPRMQFSSPS
     FVSISSECYQ FSPEFPLEIL KAKTIEMLTE AVQEGSLHVR DPVGGSTEFL FVPLIKLFYT
     LLIMGVFHNG DLKHILQLIE PRVFKEDTSQ EDENEMPEKE LTTKELKPEG GEEEARGEQV
     PKEGLLQMKL PEPVKLQMCH LLQYLCDCQI RHRIEAIVAF SDDFVAKLQE NQRFRYNEVM
     QALNMSAALT ARKTKEFRSP PQEQINMLLN FKDDKSDCPC PEEIRDQLLD FHEDLMTHCG
     IELDEDGALD GSSDLTIRGR LLYLVEKMTY LKKKQTEKPT DNHSKKPSTL QQLISDTMVR
     WAQESVIEDP ELVRAMFVLL HRQYDGIGGL VRTLPKTYTI NSVSVEDTIN LLASLGQIRS
     LLSVRMGKEE EKLMIRGLGD IMNNKVFYQH PNLMRALGMH ETVMEVMVNV LGGGESKEIT
     FPKMVANCCR FLCYFCRISR QNQKAMFDHL SYLLENSSVG LASPSMRGST PLDVAAASVM
     DNNELALALR EPDLEKVVRY LAGCGLQSCP LLISKGYPDI GWNPVEGERY LDFLRFAVFC
     NGESVEENAN VVVRLLIRRP ECFGPALRGE GGNGLLAAME EAIKISEDPT RDGPSPSNGS
     CKTLEMEEQE DDTIHVGNAI MTFYAALIDL LGRCAPEMHL IHAGKGEAIR IRSILRSLIP
     LEDLVGVISI PFHMPTIAKD GTVVEPDMSA GFCPDHKAAM VLFLDRVYGI EDQDFLLHLL
     EVGFLPDLRA AASLDTAALS ATDMALALNR YLCTAVLPLL TRCAPLFAGT EHHASLIDSL
     LHTVYRLSKG CSLTKAQRDS IEECLLSICG QLRPSMMQHL LRRLVFDVPL LNEHAKMPLK
     LLTNHYERCW KYYCLPGGWG NFGAASEEEL HLSRKLFWGI FDALSQKKYE QELFKLALPC
     LSAVAGALPP DYMESNYVSM MEKQSSMDSD GNFNPQPVDT SNSTIPEKLE YFINKYAEHS
     HDKWSMEKFA NGWIYGEMYS ESAKVQPLMK QYKLLSEKEK EIYRWPIKES LKTMLAWGWR
     IERTREGDTM ALYNRTRRIS QTSQVSVDTA HGYSPRAIDM SNVTLSRDLH AMAEMMAENY
     HNIWAKKKKM ELEAKVGGGN HPLLVPYDTL TAKEKAKDRE KAQDILKFLQ INGYIVSRGL
     KDLELDTPSI EKRFAYSFLQ QLIRYVDEAH QYILEFDGGS RGKGEHFPYE QEIKFFAKVV
     LPLIDQYFKN HRLYFLSAAS RPLSTGGHAS NKEKEMVTSL FCKLGVLVRH RISLFGNDAT
     SIVNCLHILG QTLDARTVMK TGLESVKMAL RAFLDNAAED LEKTMENLKQ GQFTHTRNQP
     KGVTQIINYT TVALLPVLSS LFEHIGQHQF GEDLILEDVQ VSCYRILASL YALGTSKSIY
     VERQRSALGE CLAAFAGAFP VAFLETHLNK HNMYSIYNTK CARDRAALDL PTSVDEVCPN
     IPSLEKLMEE IVELAESGIR YTQMPHIMEV ILPMLCSYMS HWWEHGPENN PEKAEMCCTG
     LTSEHMNTLL GNILKIIYNN LGIDEGAWMK RLAVFSQPII SKAKPQLLKT HFLPLMDKLK
     KKAAMVISDE EHLRAEGRGD MSEAELLILD EFTTLARDLY AFYPLLIRFV DYNRAKWLKE
     PNPEAEELFR MVADVFIYWS KSHNFKREEQ NFVVQNEINN MSFLITDTKS KMSKAAVSDQ
     ERKKMKRKGD RYSTQTSLIV AALKRLLPIG LNICAPGDQE LIALAKTRFS MKDTEDEVRD
     IIRSNLHLQG KLEDPAIRWQ MALYKDLPNR TENTSDPEKT VERVLDIANV LFHLEQVEHP
     QRSKKAVWHK LLSKQRKRAV VACFRMAPLY NLPRHRAVNL FLQGYEKSWI ETEEHYFEDK
     LIEDLARPGE EPPEEEESIK RVDPLHQLIL LFSRTALTEK CKLEEDFLYM AYADIMAKVT
     GSQRSKEKEM EKQKLLYQQA RLHDRGAAEM VLQTISASKG EMGPMVAATL KLGIAILNGG
     NSTVQQKMLD YLKDKKDVGF FQSLAGLMQF CSVLDLNAFE RQNKAEGLGM VTEEGSGEKV
     MQDDEFTCDL FRFLQLLCEG HNSDFQNYLR TQTGNNTTVN IIISTVDYLL RVQESISDFY
     WYYSGKDVID EQGQRNFSKA IQVAKQVFNT LTEYIQGPCT GNQQSLAHSR LWDAVVGFLH
     VFAHMQMKLS QDSSQIELLK ELMDLQKDMV VMLLSMLEGN VVNGTIGKQM VDMLVESSNN
     VEMILKFFDM FLKLKDLTSS DAFKEYDPDG KGVISKRDFQ KAMESHKHYT QSETEFLLSC
     AEPDENETLD YEEFVKRFHE PAKDIGFNVA VLLTNLSEHM PHDTRLQTFL ELAESVLNYF
     QPFLGRIEIM GSAKRIERVY FEISESSRTQ WEKPQVKESK RQFIFDVVNE GGEKEKMELF
     VNFCEDTIFE MQLAAQISES DLSERSANKE ESEKDKLEEQ DPRMGFFSLV TVKSALVALK
     YNIMTLMKML SVKSLKKQMK KMKKMTMKDM VTAFFSSYWS ILMGLLHFTS SVFRGFFRIM
     YSLLLGGSLV EGAKKIKVAE LLANMPDPTQ DEVRGEGEEG ERKPTETALP AEDLTDLTAL
     SDDGDLLSDI FGLDLKREGG QYKLIPHNPN AGLSDLLSTP SLLPLPEVQE KVQEQKVKED
     EKDEKEESKS EPEKAEGEDG EKEEKTKDEK GKQKLRQLHT HRYGEPEVQE SAFWKKIIAY
     QQKLLNYFAR NFYNMRMLAL FVAFAINFIL LFYKVSTSSV TEEKEVHVVH AGENSKLNSL
     ESGSHRIITV HYVLEESSGY MEPTLRILAI LHTVISFFCI IGYYCLKVPL VIFKREKEVA
     RKLEFDGLYI TEQPSEDDIK GQWDRLVINT QSFPNNYWDK FVKRKVMDKY GEFYGRDRIS
     ELLGMDKAAL DFSDAREKKK PKKDSSLSAV LNSIDVKYQM WKLGVVFTDN SFLYLAWYMT
     MSVLGHYNNF FFAAHLLDIA MGFKTLRTIL SSVTHNGKQL VLTVGLLAVV VYLYTVVAFN
     FFRKFYNKSE DGDMPDMKCD DMLTCYMFHM YVGVRAGGGI GDEIEDPAGD EYEIYRIIFD
     ITFFFFVIVI LLAIIQGLII DAFGELRDQQ EQVKEDMETK CFICGIGNDY FDTVPHGFET
     HTLQEHNLAN YLFFLMYLIN KDETEHTGQE SYVWKMYQER CWEFFPAGDC FRKQYEDQLN
//
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