ID A0A151MDA7_ALLMI Unreviewed; 1037 AA.
AC A0A151MDA7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Pleckstrin-like proteiny-like domain family B member 2 isoform B {ECO:0000313|EMBL:KYO22485.1};
GN Name=PHLDB2 {ECO:0000313|EMBL:KYO22485.1};
GN ORFNames=Y1Q_0003047 {ECO:0000313|EMBL:KYO22485.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO22485.1};
RN [1] {ECO:0000313|EMBL:KYO22485.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO22485.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO22485.1}.
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DR EMBL; AKHW03006231; KYO22485.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151MDA7; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR CDD; cd14673; PH_PHLDB1_2; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR037810; PHLDB1/2/3_PH.
DR PANTHER; PTHR12156:SF21; PLECKSTRIN HOMOLOGY-LIKE DOMAIN FAMILY B MEMBER 2; 1.
DR PANTHER; PTHR12156; PLECKSTRIN HOMOLOGY-LIKE DOMAIN, FAMILY B, MEMBER 3; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..1037
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007584956"
FT DOMAIN 927..1030
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 91..122
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 223..246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 399..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..703
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 553..638
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 819..885
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 91..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 683..703
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1037 AA; 119428 MW; 06711525016B0B7C CRC64;
MTVGVWSVFT WLIQAIFSIQ TDPSKIMAEY SLIQNQMELQ NASLGKSSVA NSLENDLQDI
MDNLSSKKYS SSLKFKTNGD YVGSYLTLSQ PVSTKSSPSS SVKNMHSATR IPGGTLDGKK
NSGSLLTMWN GSSGSEMMLS PVSTSGAASM PSSPKQSRRM NIQDSLNLHP RPVKHKEVMT
EALGSRARKY SGTSPSNSFS PVDIDRSFSV RRNLSTSSME FDETELESFR QTPTSLPPSI
RERKNSISSV TGREDLMDYH RRQREERLRE QEMERLERQR LETILSLCAE YSKPDSDPAA
AATVADVQKI NKELEKLQLS DEDSVFEDSQ INPETRFRNH LKLSTSDSDF SELSNVSRSA
CSFLSSRGIR ADEHIGENMK TPPLVSSAFL KDSNESSYLS ITPKTSERTS SEQRGHELGQ
LEEERIAVLN NLEELEQKIK DLNDQMDESS RELDMECALL DGEQKSETTE LLKEKEILDH
LNRKIAELER NVIGEKTKEK IKLEAEREKL ERLQELYSEQ KTQLDNCPES MREQLQQQLK
RDADLLDIES KHFEDLEFQQ LEHESRLDEE KENLTQQLLR EVAEYQRSIV SRKEKISALK
KQANHIVQQA QREQDHFVKE KNNLIMMLQR EKENLCNLEK KYSGLSGGRG FPVSPSSLKE
HFRNLEERKK QHKEGMYMSD TLPRKKTTPS VSPHFNSSTL GRSVNPKGHL PLGQSNSCGS
VLPHCLATMT KESEPRRMHK GYNHQHICEE QRQKSPEFYS RTASESNVYL NSFHYPDHSY
KDHAFDTLSL DSSDSMETSI SACSPDNISS ASTSNVARIE EMERLLKQAH AEKNRLLESR
EREMEAKKRA LEEEKRRREQ LEKRLEEETS QRQKLIEKEV KIREKQRAQA RPLTRYLPIR
KEDFDLRSHI ETAGHNIETC YHISLTEKTC RGFLIKMGGK IKTWKKRWFV FDRNKRTFSY
YSDKHETKLK GVIYFQAIEE VYYDHLKNAY KSPNPLLTFS VKTHDRIYYM VAPTPEAMRI
WMDVIVTGAE GYTHFML
//
