ID A0A151MHN3_ALLMI Unreviewed; 1915 AA.
AC A0A151MHN3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 18.
DE SubName: Full=von Willebrand factor A domain-containing protein 8 {ECO:0000313|EMBL:KYO24037.1};
GN Name=VWA8 {ECO:0000313|EMBL:KYO24037.1};
GN ORFNames=Y1Q_0004620 {ECO:0000313|EMBL:KYO24037.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO24037.1};
RN [1] {ECO:0000313|EMBL:KYO24037.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO24037.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO24037.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AKHW03006155; KYO24037.1; -; Genomic_DNA.
DR STRING; 8496.A0A151MHN3; -.
DR eggNOG; KOG1808; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011704; ATPase_dyneun-rel_AAA.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039891; VWA8.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR21610; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR21610:SF9; VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8; 1.
DR Pfam; PF07728; AAA_5; 3.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 3.
DR SUPFAM; SSF53300; vWA-like; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 454..626
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 788..897
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1566..1606
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1915 AA; 214406 MW; 7AF39062CBEBE8BF CRC64;
MQSRVLCLGG GGGSGSGSXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXAAAAGAGP
PLRALHRAAG DTVTIGDVSF KLKTPKNPEL VPQNYISDSL GQSVIHHLRW IMQKDLLGQD
VFLIGPPGPL RRSIAMQYLE LTKREAEYIA LSRDTTETDL KQRREIRAGT AFYIDQCAVR
AATEGRILVL EGLEKAERNV LPVLNNLLEN REMQLEDGRF LMSAERYDKL LQEHTKTELD
AWKIVRVSED FRVIALGLPV PKYSGNPLDP PLRSRFQARD VYYLPFRDCL QLLYSVGSNI
SADRISQLLS FAATLCSQES STLGLPDFPL DSLSAAVRIM DYFPMMSIQH LIKWLYPYNV
FLGKEGRTAV EDALKRFKLK DSGSHLCPSS ITKVESVQGS KTLQADVTVQ IGEKEVTFQV
PAGTRPLNLY SGSDTFIKTS SHKQFLAEMM QSHMVKDMCL IGGKGCGKTV IAKEFADILG
YNIEPIMLYQ DMTARDLLQQ RYTLPNGDTA WRPSPLVTAA LEGKLVILDG IHRVNSGTLA
VLQRLIHDRE LTLYDGTRLL REDRYQQLKE DLHLSDEKLQ ERSIFPIHSS FRIIALAEPP
VLGSSTQQWL GPELLTLFLF HNVKSLTKNE EFQVIKEMIP NVPKVAVEQL LSLTHKLRKT
NDPTAQSLAS SLSTRQLLRI CRRLSQYPDE SLYHAVDKAC LSRFLPNLAR SALHKNLLDS
GIETSPDDIR KLEEKNYSYE VHNGILKIGS TSMPIYNPSE KMKVPDVLFY ENTQHMMVME
DMLKDFLLGE HLLLVGNQGV GKNKIVDRFL HLLNRPREYL QLHRDTTVQS LTQQPSVKDG
LIMYEDSPLV KAVKSGHILV IDEADKAPTN VTCILKTLVE SGEMILSDGR RLVANPATVD
GRENVIVIHP DFRMIVLANR PGFPFLGNDF FGTLGDIFSC HAVDNPKPQS ELSMLKQYGP
DVPKQVLQKL VAAFGELRSL ADQGIINYPY STREVVNIVK HLQKFPTEGL ADVVRNVFDF
DSYNNEMRET LINTLHKHGI PIGAKPTNIQ LAKELPLPDH KFMGYWRVGQ SGNAQQKLLC
PTETQHVNVK GPVYLNIQGF PLERHEARSL SFTEELAFWT LPLNEVNLVC DIAVAQEEEA
DNILYVATCN PISLYFMNVS GKNGYFVDFY DLFPRTVGSM WQPFVTVAPL GNPLKGQVIL
HEQQSNVVLL LDTNNGTIRR LLFSPEAEEA PKRMSWWGNK EELSNHKMCR EFSHKNWLVF
YKEGGNYLTV LDVLEGQTHT ISLPINLKSV FLVAEDRWLV VENNTNQKFL LTKQVHMESE
ESGVCQLHVL SDEPVDTGFG LTAASELCVP HAVSSDQLSS ENLSVAVGQK ISSPNRIISD
EHNYATIVVG FPDLMSPNEV YSWRRRSSLS SRHASPSDPF YYGGLRKTGA PKQINCMALL
ASNQVVRILA PGDVPLKEIY PKEVTPPPTA GYMEITDLNS KKLKYIPIPR SGSLSLYTSW
LSKISDTDVL LAPLGKVGLV TVDMGGSVRL WETGLDSLQR SLQDWRNMIG QEDGRPMQIT
IERDSGLDVS SPKHGKIDQD NMPHVGGNTW AGGTGGRDTA GLGGKGGPYR LDAGHKVYQI
SQAEKDAVPE EVKRAAREMG EKAFKQRLKE IKMSEYDAST YERFSGAVRR QVQSLRIILD
NLQAKGKERQ WLKHQAVGEL DDAKIIDGLT GEKAIYKRRG ELEPQPGSPQ QKPKRLRLVV
DVSGSMYRFN GVDGRLERSM EAVCMVMEAF ENYEHKFKYD IVGHSGDGFN IALVGSDKVP
KNNKQRLEIL KIMHAHAQFC MSGDHTLEGT EHAVREIAKE DADEYFVIVL SDANLERYGI
PPARRPSRQA AEDTTSRPVF YCHGYQADPT DHAADLYIHH VVKCLSVLTA IAVRM
//
