ID A0A151MXU5_ALLMI Unreviewed; 402 AA.
AC A0A151MXU5;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Tumor necrosis factor receptor superfamily member 11B {ECO:0000313|EMBL:KYO29268.1};
GN Name=TNFRSF11B {ECO:0000313|EMBL:KYO29268.1};
GN ORFNames=Y1Q_0017919 {ECO:0000313|EMBL:KYO29268.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO29268.1};
RN [1] {ECO:0000313|EMBL:KYO29268.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO29268.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00206}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO29268.1}.
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DR EMBL; AKHW03004704; KYO29268.1; -; Genomic_DNA.
DR RefSeq; XP_006263409.2; XM_006263347.3.
DR AlphaFoldDB; A0A151MXU5; -.
DR STRING; 8496.A0A151MXU5; -.
DR GeneID; 102565506; -.
DR KEGG; amj:102565506; -.
DR CTD; 4982; -.
DR eggNOG; ENOG502QVRT; Eukaryota.
DR OrthoDB; 5348767at2759; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01670; Death; 1.
DR CDD; cd00185; TNFRSF; 1.
DR CDD; cd10581; TNFRSF11B; 1.
DR Gene3D; 1.10.533.10; Death Domain, Fas; 1.
DR Gene3D; 2.10.50.10; Tumor Necrosis Factor Receptor, subunit A, domain 2; 4.
DR InterPro; IPR011029; DEATH-like_dom_sf.
DR InterPro; IPR000488; Death_domain.
DR InterPro; IPR001368; TNFR/NGFR_Cys_rich_reg.
DR InterPro; IPR022323; TNFR_11.
DR InterPro; IPR017371; TNFR_11B.
DR PANTHER; PTHR23097; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER; 1.
DR PANTHER; PTHR23097:SF90; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 11B; 1.
DR Pfam; PF00531; Death; 1.
DR Pfam; PF00020; TNFR_c6; 3.
DR PRINTS; PR01961; TNFACTORR11.
DR PRINTS; PR01975; TNFACTORR11B.
DR SMART; SM01411; Ephrin_rec_like; 2.
DR SMART; SM00208; TNFR; 4.
DR SUPFAM; SSF47986; DEATH domain; 1.
DR SUPFAM; SSF57586; TNF receptor-like; 2.
DR PROSITE; PS50050; TNFR_NGFR_2; 2.
PE 4: Predicted;
KW Apoptosis {ECO:0000256|ARBA:ARBA00022703};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00206}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Receptor {ECO:0000313|EMBL:KYO29268.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..402
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007585565"
FT REPEAT 64..105
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DOMAIN 64..105
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT DOMAIN 106..142
FT /note="TNFR-Cys"
FT /evidence="ECO:0000259|PROSITE:PS50050"
FT REPEAT 106..142
FT /note="TNFR-Cys"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 65..80
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 87..105
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
FT DISULFID 124..142
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00206"
SQ SEQUENCE 402 AA; 45796 MW; E4366EFAD6FFF7E8 CRC64;
MNRVLCCALV FLDISIKWAT QETSPPKYLH YDPATSRQLM CDLCPPGTYL KQHCTATRKT
ECSPCPDQYY SEDWNSNDEC QYCSVVCKEL QYVKQECNST QNRICECIEG RYLDLEFCLK
HTECPPGSGV VQPGTPESDT SCMRCPEGFF SNETSSKTPC KKHTNCSALG LKTASKGNAV
RDNVCQGNGD ASAQKCGIDV TLCEEALFRF TVPTQLSPNW LNILADNLPG TKITTENIEW
IKQRHSSQEQ AFQLLKLWKQ QNKEQDMVKK KIRDFDLCEN SVLKHVGQLN LSFEHLNILM
ASLPGKKVGK EDIERTVKLC TPTQQILKLL NLWRVKNGDQ DTINGLMFGL KHLKTYHFPK
TTIQSLKKVV KILHRFTTYR VSQKLFLDRV GNQVKMVKMR SV
//
