ID   A0A151N177_ALLMI        Unreviewed;       958 AA.
AC   A0A151N177;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 20.
DE   SubName: Full=MHC class II transactivator isoform A {ECO:0000313|EMBL:KYO30510.1};
GN   Name=CIITA-1 {ECO:0000313|EMBL:KYO30510.1};
GN   ORFNames=Y1Q_0008169 {ECO:0000313|EMBL:KYO30510.1};
OS   Alligator mississippiensis (American alligator).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC   Alligator.
OX   NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO30510.1};
RN   [1] {ECO:0000313|EMBL:KYO30510.1, ECO:0000313|Proteomes:UP000050525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO30510.1};
RX   PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA   St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA   Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA   Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA   Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA   Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA   McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA   Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA   Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA   Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA   Ray D.A.;
RT   "Sequencing three crocodilian genomes to illuminate the evolution of
RT   archosaurs and amniotes.";
RL   Genome Biol. 13:415-415(2012).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KYO30510.1}.
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DR   EMBL; AKHW03004154; KYO30510.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A151N177; -.
DR   STRING; 8496.A0A151N177; -.
DR   eggNOG; KOG4308; Eukaryota.
DR   Proteomes; UP000050525; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR008095; MHC_II_transact.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR47189; MHC CLASS II TRANSACTIVATOR; 1.
DR   PANTHER; PTHR47189:SF1; MHC CLASS II TRANSACTIVATOR; 1.
DR   Pfam; PF13516; LRR_6; 2.
DR   Pfam; PF05729; NACHT; 1.
DR   PRINTS; PR01719; MHCIIACTVATR.
DR   SMART; SM00368; LRR_RI; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52047; RNI-like; 1.
DR   PROSITE; PS51450; LRR; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT   DOMAIN          484..628
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|PROSITE:PS50837"
SQ   SEQUENCE   958 AA;  107368 MW;  5ECD504A264035AD CRC64;
     MNLFKEILPR VRKILSSATL SDAHALLSLM LKEDVISKEY YQTLLHEKDR EDLARKISLT
     FVEKWDLCLN TLVPLCYLKL CNNKHQSTTD GDSSLNRVLA GNKRQTMDSS ILTENSFLDL
     LHSDIDPVHL YTLLDAKSIE NAESEVLTDP ETDTINHDQF NNLDIFYTME NSESGEELYI
     CSNTREAYAR IAGLAEYVLK DPQERQMEDT FAGNLIFDEM ATESTEGFTD VKMQKCHKRT
     FLGTAENHSD TSEPKCRKTV DSPAVSTVNS SFLSVTLSGS PVNSSSFSLL HIPFSVTTIS
     PTGRSFIAPG SIPNCLPVSA KGIQVIPGFP ALPQQIISLP VRNGASDIIV CPGSSFPTET
     SQLASPILPV NLSGVEISKG SQIPFVPSKQ TQKRPKPVEA FCMSLKDYFC DVCKFMPMER
     EVTLDQLYIE GALLQGQHET KGGKNIIKGI EKEPVIYDLE EKEKTALERN QIFQVPGGKE
     LETKIIVLLG KAGMGKSILV QKICQDWSNG KFSQFEFVFL YECRRLSLPE KRYSLKDLLL
     EVFVRPQEGK EEVFKYILQN PSKVLLIFDG FEELQDHDGF THFPDCQSYK ELYSMRELFA
     GLFQKKILSG CTLLLTARPK DKLNQYLSKV DKIIEMVGFS PQQNIALRLE RELSFLGTPL
     TPPDVYVLRS ILKRSKKEFA LDLRNSAIDL QGMKDLVGLK NVTSFRASLT DTIRLWESLE
     QTQEYELLKI SIQKFAIDPF KAKTMRDISD LSGFVHMQEK MIHCMQETSG CQIHEIPAIK
     NLKKLEFALG PACGPRGFLR LVEILVSLPS LQQLDLDALS ENGIGDEGVK SLSQVFSQLT
     SLEVLNLSQN KITDLGAENL ATALPSLSSL KTLSLYNNSI CDAGAENIAK VLPAMASLRV
     LDVQAWRCGI LLFPMEFLST CSNWILELFC RFSRSCEGDI KKKGKEISLT FLIMFAAL
//