ID A0A151NGQ6_ALLMI Unreviewed; 1732 AA.
AC A0A151NGQ6;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Unconventional myosin-Vb {ECO:0008006|Google:ProtNLM};
GN ORFNames=Y1Q_0011975 {ECO:0000313|EMBL:KYO35982.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO35982.1};
RN [1] {ECO:0000313|EMBL:KYO35982.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO35982.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the TRAFAC class myosin-kinesin ATPase
CC superfamily. Myosin family. {ECO:0000256|PROSITE-ProRule:PRU00782}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO35982.1}.
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DR EMBL; AKHW03003034; KYO35982.1; -; Genomic_DNA.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR GO; GO:0003779; F:actin binding; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003774; F:cytoskeletal motor activity; IEA:UniProtKB-UniRule.
DR CDD; cd15470; Myo5_CBD; 1.
DR CDD; cd01380; MYSc_Myo5; 1.
DR Gene3D; 1.10.10.820; -; 1.
DR Gene3D; 1.20.5.190; -; 3.
DR Gene3D; 1.20.58.530; -; 1.
DR Gene3D; 6.20.240.20; -; 1.
DR Gene3D; 3.40.850.10; Kinesin motor domain; 1.
DR Gene3D; 1.20.120.720; Myosin VI head, motor domain, U50 subdomain; 1.
DR InterPro; IPR002710; Dilute_dom.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR036961; Kinesin_motor_dom_sf.
DR InterPro; IPR001609; Myosin_head_motor_dom.
DR InterPro; IPR036103; MYSc_Myo5.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13140; MYOSIN; 1.
DR PANTHER; PTHR13140:SF356; UNCONVENTIONAL MYOSIN-VB; 1.
DR Pfam; PF01843; DIL; 1.
DR Pfam; PF00612; IQ; 5.
DR Pfam; PF00063; Myosin_head; 1.
DR PRINTS; PR00193; MYOSINHEAVY.
DR SMART; SM01132; DIL; 1.
DR SMART; SM00015; IQ; 6.
DR SMART; SM00242; MYSc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51126; DILUTE; 1.
DR PROSITE; PS50096; IQ; 5.
DR PROSITE; PS51456; MYOSIN_MOTOR; 1.
PE 3: Inferred from homology;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Coiled coil {ECO:0000256|SAM:Coils};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Myosin {ECO:0000256|ARBA:ARBA00023123, ECO:0000256|PROSITE-
KW ProRule:PRU00782};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00782}; Reference proteome {ECO:0000313|Proteomes:UP000050525}.
FT DOMAIN 69..751
FT /note="Myosin motor"
FT /evidence="ECO:0000259|PROSITE:PS51456"
FT DOMAIN 1413..1685
FT /note="Dilute"
FT /evidence="ECO:0000259|PROSITE:PS51126"
FT REGION 630..652
FT /note="Actin-binding"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
FT REGION 1083..1132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1321..1354
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 886..937
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 969..1082
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1167..1194
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1223..1319
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1087..1126
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 163..170
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00782"
SQ SEQUENCE 1732 AA; 198953 MW; 0105859151F0F371 CRC64;
MAAPDLYAQG AQVWIPDCVE VWKPAEVTRG YKEGDGVLYL RLEDGQEVAY PLDPYCLQLP
HLRNPDYLSG ENNLVALSYL HEPAVLHTLR MRFLESSTIY TYCGIVLVAV NPYKQLPIYE
EAVIHAYSGQ NIGEMDPHIF AVAEEAYRQM SREDKNQSLI ISGESGAGKT ATAKYAMREK
QQSSSSTARF LAREAFGNAK TTRNDNSSRF GKYVEICFNH EYRVLGATMK TYLLEKSRVT
FQATVERNYH IFYQLCASAS LPELQGLGLG GPESFHYTNQ GQCMHIGGTD DAADLDRTRN
AFSLLGVSEA DQLELFSILA AILHLGNIRL KKKSRHGESC FIEAEDKALE LFCMLLGLEM
SQVSRWLCYH KLVTASETFV KPMSWQQVLD SRDALAKHIY GQLFQWVVSR INRSLRASER
HRASIGILDI YGFETFRVNS FEQFCINYAN EKLQQHFNLH VFKLEQEEYV EEGIPWTFID
FYDNQPCIDL IEAKLGILDL LNEECKMPNG SDGSWAQKLY DRHLHHSLHF EKPKMHADAF
IIQHFAGKVE YQCKGFLEKN RDAVHAELIG LLRASKSQLL AELFPEDCDG TISLRRSNGT
RLTVRPSRKS LPGTNKEHRK PISVQFKASL HKLMEMLGCT MPHYIRCIKP NDLKRPFEFD
SKRAIEQLRA CGILETIQIS ASGYPSRWTY EDFFSRYRAL MSRVELTGDD EKKICRLVLE
RLLRDPSKYQ CGRRKVFLRA GQVAFLEELR AKTLRAACII LQSSLRGWLG RRRFLLVHAA
AICIQRFARG LLARRLVRDL RRAKAAVILQ KNIKMALARR SYLRIHVAII TIQAFTRGMF
ARHLYRVMVL HQKAVVIQAA VRGWLARSHY TRLRHAAVYL QCCFRRSRAR RELKQLRIEA
RSVEHYKQLQ KGMEIKVMQL QCKLDEQARE NRSLLEQLSM LSTSHAEEVE RLCGEMQQLR
EDKAQDQHIQ GLQEQLQCVE LEKRSSERRL CQELEQLKQR MTELEVAKSN LKDENDTLNR
RILEQSKDVE EKMCQRLSVE SRELQCELEE ERSRYQSLVK EYARLEQGYE NLREEVAFHK
HTTGFRRSPS SDSILDSESS YQSGSTALSR DEPVQQIESP SQPLNQEKDP WRLIPEQYRA
RSDSTTSSLS SDGEQDPLKA YILLGQLNAV RKELARTQEE LHKTKTQLAH EDKKLLRPWY
IAELFGLNRS PEKMMEEDLK HAYDAVQVTN RLLEEQLQEQ QQQHKQEREG LHQDIRSLKR
LTWQQQSLIQ DLQHQQSGDG LQRQIVQLKE ENLELSEQLQ KQERSKLKLQ KQLKNYMKQI
QEPAATREAT RGEKATPAEQ ERPLEVPSPS GPFQGMLRCR GEDEERLVRT IITDFQPQHI
PGTLPTLPGY ILFMCLRHAD YCQDEHRIRS LLTAAINGIK RVMKKHSEDF DMVTFWLANT
CCLLNCLRQY GRDESYRQVN TPKQNLHCLQ HCNPVSHCQS LGDLAIQIYQ QLIGTAEKKL
KPMIVAAMLE SETIPGLSST RPSGSRRPQG APAYTLDSLL LQLSAFHKVL KSHDLEPAIV
QQAVRQLLFL ISGTALNYLL LRRDACSWSQ GVQLRYNVSQ LEEWLRTGGL QQSGATTILE
PLIQAAQLLQ VKKTSEEDAE AICCLCTALS PQQVVKLLRA YTPAPGLEER VSPHFISSVE
KRLAEQNPSG PCQLLVDTAQ LFPVPLPFSH SPVHLDEICL PDGLNLTFLS CM
//
