ID A0A151NHG9_ALLMI Unreviewed; 397 AA.
AC A0A151NHG9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Lipase member I isoform B {ECO:0000313|EMBL:KYO36089.1};
GN Name=LIPI {ECO:0000313|EMBL:KYO36089.1};
GN ORFNames=Y1Q_0013129 {ECO:0000313|EMBL:KYO36089.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO36089.1};
RN [1] {ECO:0000313|EMBL:KYO36089.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO36089.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|RuleBase:RU004262}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO36089.1}.
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DR EMBL; AKHW03003018; KYO36089.1; -; Genomic_DNA.
DR RefSeq; XP_014460061.1; XM_014604575.2.
DR AlphaFoldDB; A0A151NHG9; -.
DR GeneID; 102566291; -.
DR CTD; 200879; -.
DR OrthoDB; 3428256at2759; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016298; F:lipase activity; IEA:InterPro.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd00707; Pancreat_lipase_like; 1.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR013818; Lipase.
DR InterPro; IPR033906; Lipase_N.
DR InterPro; IPR000734; TAG_lipase.
DR PANTHER; PTHR11610; LIPASE; 1.
DR PANTHER; PTHR11610:SF186; LIPASE H-RELATED; 1.
DR Pfam; PF00151; Lipase; 1.
DR PRINTS; PR00821; TAGLIPASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..397
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007586070"
FT DOMAIN 36..241
FT /note="Lipase"
FT /evidence="ECO:0000259|Pfam:PF00151"
SQ SEQUENCE 397 AA; 44783 MW; 82EED07008ABBA42 CRC64;
MLRLHIIFIF IFTCRVGADT EEACPAFTGL SISSALTGTD LKVKLLLYTR QNQHCAETLS
TVASNYLNVT KKSIFIVHGY RPTGSPPVWI QDIIKLLLSI EDVNIIIVDW NRGATTLIYH
NAFRKTRKVA EFLKERIDRM LAEGASLDSI YLIGISLGAH ISGFVGQMYN GRLGRITALD
PAGPLFRGKP HSERLDPSDA QFVDVIHSDI DGLGYREALG HIDFYPNGGT DQPGCPQTIF
SGYYAYEWKS HLTQKDPPVT KAFFDTADKE PFCIYHYFVD VITWNQNMRR GSLTIKLTDQ
AGNTAKSRIN HEAAVFQQHR QTILLTGFDQ DLDEVQRMSL TFSTGTVVGP KYKLRILQMR
LWSISNPERP ALCRYDLVLM ENVEIGFKPI PCESRPT
//
