ID A0A151NPK2_ALLMI Unreviewed; 768 AA.
AC A0A151NPK2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Semaphorin-3A {ECO:0008006|Google:ProtNLM};
GN ORFNames=Y1Q_0023411 {ECO:0000313|EMBL:KYO38713.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO38713.1};
RN [1] {ECO:0000313|EMBL:KYO38713.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO38713.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- SIMILARITY: Belongs to the semaphorin family.
CC {ECO:0000256|ARBA:ARBA00009492}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO38713.1}.
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DR EMBL; AKHW03002440; KYO38713.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151NPK2; -.
DR STRING; 8496.A0A151NPK2; -.
DR eggNOG; KOG3611; Eukaryota.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR CDD; cd05871; Ig_Sema3; 1.
DR CDD; cd11249; Sema_3A; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR013151; Immunoglobulin.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR042820; Sema3A_sema.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF23; SEMAPHORIN-3A; 1.
DR Pfam; PF00047; ig; 1.
DR Pfam; PF01403; Sema; 1.
DR SMART; SM00409; IG; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS50835; IG_LIKE; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..768
FT /note="Semaphorin-3A"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007586239"
FT DOMAIN 30..513
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT DOMAIN 575..664
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 768 AA; 87895 MW; AE4B7648ADBCD16C CRC64;
MGRLGGAALL LLLAGLLLAA CQPGRNNVPR LKLSYKEMLE SNNIITFNGL SNSSSYHTFL
LDEERSRLYV GAKDHIFSFN LVNIKEYRKI VWPVSHTRRD ECKWAGKDIL KECANFIKVL
KAYNHTHLYA CGTGAFHPIC TYIEIGRHPE DNIFKIEDSH FENGRGKSPY DPKLLTASLL
IDGELYSGTA ADFMGRDFAI FRTLGHHHPI RTEQHDSRWL NDPRFISAHL IPESDNPEDD
KIYFFFRENA IDGEHSGKAT HARIGQICKN DFGGHRSLVN KWTTFLKARL ICSVPGPNGI
DTHFDELQDV FLMNSKDPKN PIVYGVFTTS SNIFKGSAVC MYSMTDVRRV FLGPYAHRDG
PNYQWVPYQG RVPYPRPGTC PSKTFGGFDS TKDLPDEVIT FARSHPAMYN PVFPINNRPI
MIKTDVDYQF TQIVVDRVDA EDGQYDVMFI GTDIGTVLKV VSIPKETWHD LEEVLLEEMA
VFREPTIISA MKISTKQQQL YIGSATGVSQ LPLHRCDVYG KACAECCLAR DPYCAWDGSS
CSRYFPTAKR RTRRQDIRNG DPLTHCSDLQ HHDNPSGQSL EEKIIYGVEN SSTFLECSPK
SQRALVYWQF QKQNEDRKEE IKVDDRLIRT DQGLLLRTLQ RKDSGTYFCH AVEHGFMQTL
LKVTLEVIDS EHLEELLHKE EDGESSKVKE ASNSMTPSQK VWYRDFMQLI NHPNLNTMDE
FCEQVWKRDR KQRRQRPANA QIHLAVWSIA TVIFFLSEQM NCFAASEH
//
