ID A0A151PBY3_ALLMI Unreviewed; 1227 AA.
AC A0A151PBY3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:KYO46591.1};
GN ORFNames=Y1Q_0018366 {ECO:0000313|EMBL:KYO46591.1};
OS Alligator mississippiensis (American alligator).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Crocodylia; Alligatoridae; Alligatorinae;
OC Alligator.
OX NCBI_TaxID=8496 {ECO:0000313|EMBL:KYO46591.1};
RN [1] {ECO:0000313|EMBL:KYO46591.1, ECO:0000313|Proteomes:UP000050525}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=KSC_2009_1 {ECO:0000313|EMBL:KYO46591.1};
RX PubMed=22293439; DOI=10.1186/gb-2012-13-1-415;
RA St John J.A., Braun E.L., Isberg S.R., Miles L.G., Chong A.Y., Gongora J.,
RA Dalzell P., Moran C., Bed'hom B., Abzhanov A., Burgess S.C., Cooksey A.M.,
RA Castoe T.A., Crawford N.G., Densmore L.D., Drew J.C., Edwards S.V.,
RA Faircloth B.C., Fujita M.K., Greenwold M.J., Hoffmann F.G., Howard J.M.,
RA Iguchi T., Janes D.E., Khan S.Y., Kohno S., de Koning A.J., Lance S.L.,
RA McCarthy F.M., McCormack J.E., Merchant M.E., Peterson D.G., Pollock D.D.,
RA Pourmand N., Raney B.J., Roessler K.A., Sanford J.R., Sawyer R.H.,
RA Schmidt C.J., Triplett E.W., Tuberville T.D., Venegas-Anaya M.,
RA Howard J.T., Jarvis E.D., Guillette L.J.Jr., Glenn T.C., Green R.E.,
RA Ray D.A.;
RT "Sequencing three crocodilian genomes to illuminate the evolution of
RT archosaurs and amniotes.";
RL Genome Biol. 13:415-415(2012).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYO46591.1}.
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DR EMBL; AKHW03000499; KYO46591.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151PBY3; -.
DR Proteomes; UP000050525; Unassembled WGS sequence.
DR GO; GO:0001518; C:voltage-gated sodium channel complex; IEA:InterPro.
DR GO; GO:0005248; F:voltage-gated sodium channel activity; IEA:InterPro.
DR CDD; cd13433; Na_channel_gate; 1.
DR Gene3D; 1.10.287.70; -; 3.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 3.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR044564; Na_chnl_inactivation_gate.
DR InterPro; IPR010526; Na_trans_assoc_dom.
DR InterPro; IPR043203; VGCC_Ca_Na.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR10037:SF223; SODIUM CHANNEL PROTEIN TYPE 4 SUBUNIT ALPHA; 1.
DR PANTHER; PTHR10037; VOLTAGE-GATED CATION CHANNEL CALCIUM AND SODIUM; 1.
DR Pfam; PF00520; Ion_trans; 3.
DR Pfam; PF06512; Na_trans_assoc; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Ion channel {ECO:0000256|ARBA:ARBA00022882};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000050525};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448};
KW Voltage-gated channel {ECO:0000256|ARBA:ARBA00022882}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..1227
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007586887"
FT TRANSMEM 92..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 236..253
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 273..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 471..489
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 501..524
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 581..609
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 639..659
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 671..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 905..923
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 944..966
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 972..992
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1021..1047
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1145..1168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..307
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 470..699
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 708..899
FT /note="Sodium ion transport-associated"
FT /evidence="ECO:0000259|Pfam:PF06512"
FT DOMAIN 903..1177
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 346..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 743..762
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1198..1227
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 297..339
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 743..758
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1227 AA; 140108 MW; 7E44B9808F0C3A2E CRC64;
MFIMITILTN CVFMTMSDPP PWSKNVEYTF TGIYTFESMI KILARGFCID SFTFLRDPWN
WLDFSVIVMA YTTEFVDLGN ISALRTFRVL RALKTITVIP GLKTIVGALI QSVKKLSDVM
ILTVFCLSVF ALIGLQLFMG NLRHKCVRWP PPFNETIPEN IFGMDNDTFV NATLYGNLTG
SGNNTFDYDA YMNNEGNFYF LEGALDALLC GNSSDAGKCP EGYECMKAGR NPNYGYTSYD
TFSWAFLALF RLMTQDYWEN LFQLTLRAAG KTYMIFFVLI IFLGSFYLIN LILAVVAMAY
AEQNDATALE IQQKEEEYQK LLEQLKKHQE EQAKMLKDRK LSACSATQKK KGDSDQDADS
DQDKLKDCNG RVVPKVVLER SATVRERNPS DDQDKVDYNH LAVGPQDGPS LQKRAESVTS
IISSTMEELE EAHRKCPPWW YKFAKTFLVW DCCLPWLKLK AFVKLIVLDP FVDLGITICI
VLNTLFMAME HYPMTEEFEN VLTVGNLVFT GIFTAEMVLK LIALDPYDYF QQGWNIFDSI
IVTLSLVELG LANVQGLSVL RSFRLLRVFK LAKSWPTLNM LIKIIGNSVG ALGNLTLVLA
IIVFIFAVVG MQLFGKSYKE CVCKISADCT LPRWHMHDFF HAFLIVFRIL CGEWIETMWD
CMEVAGQAMC LLVFMLVMVI GNLVVLNLFL ALLLSSFSAD SLAASDDDGE MNNLQIAIGR
ITRGIDFVKK TVLMLLHRQW KEKKDPDEEQ EESKTDNYVL NHMDSGQDSK SDFMDGVAGK
EHISVDHVDH MNFINNPNLT VQVPIASEES DLYDETSTQS DTEDTKKPLS HGSTSSMGST
VDYKPPVAEV EEVVEEATEG TEPENCFTEA CVQRFPFLYV DITTDKGKIW WNLRKTCFKI
VEHNWFETFI IFMILLSSGA LAFEDIYIEQ RKVIRTILEY ADKIFSYVFV IEMLLKWVAY
GFKVYFTNAW CWLDFLIVDV SIISLTANWL GYSELGAIKS LRTLRALRPL RALSRFEGMR
VVVNALLGAI PSIMNVLLVC LIFWLIFSIM GVNLFAGKYY RCINTTTDEL FEIEVVNNKS
DCLALLDTSQ VRWVNVKVNF DNVGLGYLSL LQVATFKGWM DIMYAAVDSR EIEEQPLYET
NLYMYIYFVI FIIFGAFFTL NLFIGVIIDN FNQQKKKFGG KDIFMTEEQK KYYNAMKKLG
SKKPQKPIPR PQMTKVKPKL KFSRLST
//
