ID A0A151R7G9_CAJCA Unreviewed; 757 AA.
AC A0A151R7G9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Phosphatidylinositol 4-phosphate 5-kinase {ECO:0000256|PIRNR:PIRNR037274};
DE EC=2.7.1.68 {ECO:0000256|PIRNR:PIRNR037274};
GN ORFNames=KK1_040307 {ECO:0000313|EMBL:KYP38449.1};
OS Cajanus cajan (Pigeon pea) (Cajanus indicus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Cajanus.
OX NCBI_TaxID=3821 {ECO:0000313|EMBL:KYP38449.1, ECO:0000313|Proteomes:UP000075243};
RN [1] {ECO:0000313|EMBL:KYP38449.1, ECO:0000313|Proteomes:UP000075243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Asha {ECO:0000313|Proteomes:UP000075243};
RX PubMed=22057054; DOI=10.1038/nbt.2022;
RA Varshney R.K., Chen W., Li Y., Bharti A.K., Saxena R.K., Schlueter J.A.,
RA Donoghue M.T., Azam S., Fan G., Whaley A.M., Farmer A.D., Sheridan J.,
RA Iwata A., Tuteja R., Penmetsa R.V., Wu W., Upadhyaya H.D., Yang S.P.,
RA Shah T., Saxena K.B., Michael T., McCombie W.R., Yang B., Zhang G.,
RA Yang H., Wang J., Spillane C., Cook D.R., May G.D., Xu X., Jackson S.A.;
RT "Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop
RT of resource-poor farmers.";
RL Nat. Biotechnol. 30:83-89(2012).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol 4-
CC phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-
CC inositol-4,5-bisphosphate) + ADP + H(+); Xref=Rhea:RHEA:14425,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:58178,
CC ChEBI:CHEBI:58456, ChEBI:CHEBI:456216; EC=2.7.1.68;
CC Evidence={ECO:0000256|PIRNR:PIRNR037274};
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DR EMBL; KQ484000; KYP38449.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A151R7G9; -.
DR STRING; 3821.A0A151R7G9; -.
DR OMA; GEFRDGF; -.
DR Proteomes; UP000075243; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProt.
DR GO; GO:0016308; F:1-phosphatidylinositol-4-phosphate 5-kinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0046488; P:phosphatidylinositol metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd17302; PIPKc_AtPIP5K_like; 1.
DR Gene3D; 3.30.810.10; 2-Layer Sandwich; 1.
DR Gene3D; 2.20.110.10; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 4.
DR Gene3D; 3.30.800.10; Phosphatidylinositol Phosphate Kinase II Beta; 1.
DR InterPro; IPR003409; MORN.
DR InterPro; IPR017163; PIno-4-P-5_kinase_pln.
DR InterPro; IPR027483; PInositol-4-P-4/5-kinase_C_sf.
DR InterPro; IPR002498; PInositol-4-P-4/5-kinase_core.
DR InterPro; IPR027484; PInositol-4-P-5-kinase_N.
DR InterPro; IPR023610; PInositol-4/5-P-5/4-kinase.
DR PANTHER; PTHR23086:SF113; PHOSPHATIDYLINOSITOL 4-PHOSPHATE 5-KINASE 6; 1.
DR PANTHER; PTHR23086; PHOSPHATIDYLINOSITOL-4-PHOSPHATE 5-KINASE; 1.
DR Pfam; PF02493; MORN; 7.
DR Pfam; PF01504; PIP5K; 1.
DR PIRSF; PIRSF037274; PIP5K_plant_prd; 1.
DR SMART; SM00698; MORN; 7.
DR SMART; SM00330; PIPKc; 1.
DR SUPFAM; SSF82185; Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain; 2.
DR SUPFAM; SSF56104; SAICAR synthase-like; 1.
DR PROSITE; PS51455; PIPK; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|PIRNR:PIRNR037274, ECO:0000256|PROSITE-
KW ProRule:PRU00781};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000256|PIRNR:PIRNR037274};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR037274, ECO:0000256|PROSITE-
KW ProRule:PRU00781}; Reference proteome {ECO:0000313|Proteomes:UP000075243};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR037274}.
FT DOMAIN 359..753
FT /note="PIPK"
FT /evidence="ECO:0000259|PROSITE:PS51455"
SQ SEQUENCE 757 AA; 86109 MW; 91B115DA67F344EE CRC64;
MSKEINGIVK AWETTVRKSS GAKKRTNSIF TPMFVAHVDD DESAAVCQVE KILPNGDFYT
GQWLQRFPHG QGKYLWTDGC MYVGEWSKGT TTGKGRFSWP SGATYEGEFK CGNMDGKGTY
IGSSGDTYKG SWMMNFKHGQ GTESYPNGDF YDGEWKKGLH NGHGRYQWKN GNQYIGQWKN
GVFCGNGTMM WSNGNRYDGC WEEGLPKGNG TFRWGDGSFY VGVWSQDPKE QSGTFYPGAS
DRPADWDPQD VFNVELIDCQ ICPCEKVSIY PSQKTLSVSC GEEDNKLVSK KRIDGSGRPR
WTSEDGRISN YNSECEDGAY AFDVARKSGF DASVDHSNQG RDTSLSRLRI KNPKRQGETI
SKGHKNYELM LNLQLGIRHS VGRPAPSASL DLKNSAFDPK EKVWTRFPPE GSKHTPPHPS
CEFRWKDYCP VVFRALRKLF KVDPADYMIS ICGNDALREL SSPGKSGSFF YLTNDDRYMI
KTMKKAEVKV FMRMLPAYYK HVRAFENTLV TRFYGLHCVK LTGSAQKKVR FVIMGNLFCS
QHAIHKRFDL KGSTFGRNTD KPESEIEPTT TLKDLDLNFI FRLQKSWFQE FCRQVDRDCD
FLEQERIMDY SMLVGLHFKE TTSSGTVTPS RHSTSGCTPT SFNDAGPRLS GVDIDHLIMD
PSRWIQLGVN MPARAEMTMR KSTSDTPQLV GQPTGELYEI IIFFGIIDIL QDYDISKKLE
HAYKSFQYDP TSISAVDPRL YSKRFRDFIF RVFVEDT
//
