ID A0A151RCR7_CAJCA Unreviewed; 1399 AA.
AC A0A151RCR7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Cucumisin {ECO:0000313|EMBL:KYP40420.1};
DE EC=3.4.21.62 {ECO:0000313|EMBL:KYP40420.1};
GN ORFNames=KK1_038228 {ECO:0000313|EMBL:KYP40420.1};
OS Cajanus cajan (Pigeon pea) (Cajanus indicus).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Cajanus.
OX NCBI_TaxID=3821 {ECO:0000313|EMBL:KYP40420.1, ECO:0000313|Proteomes:UP000075243};
RN [1] {ECO:0000313|EMBL:KYP40420.1, ECO:0000313|Proteomes:UP000075243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Asha {ECO:0000313|Proteomes:UP000075243};
RX PubMed=22057054; DOI=10.1038/nbt.2022;
RA Varshney R.K., Chen W., Li Y., Bharti A.K., Saxena R.K., Schlueter J.A.,
RA Donoghue M.T., Azam S., Fan G., Whaley A.M., Farmer A.D., Sheridan J.,
RA Iwata A., Tuteja R., Penmetsa R.V., Wu W., Upadhyaya H.D., Yang S.P.,
RA Shah T., Saxena K.B., Michael T., McCombie W.R., Yang B., Zhang G.,
RA Yang H., Wang J., Spillane C., Cook D.R., May G.D., Xu X., Jackson S.A.;
RT "Draft genome sequence of pigeonpea (Cajanus cajan), an orphan legume crop
RT of resource-poor farmers.";
RL Nat. Biotechnol. 30:83-89(2012).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; KQ483836; KYP40420.1; -; Genomic_DNA.
DR STRING; 3821.A0A151RCR7; -.
DR OMA; PFGTIHK; -.
DR Proteomes; UP000075243; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 2.
DR CDD; cd04852; Peptidases_S8_3; 2.
DR Gene3D; 2.60.40.2310; -; 2.
DR Gene3D; 3.50.30.30; -; 2.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 2.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 2.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF791; SUBTILISIN-LIKE SERINE ENDOPEPTIDASE FAMILY PROTEIN; 1.
DR Pfam; PF17766; fn3_6; 2.
DR Pfam; PF05922; Inhibitor_I9; 2.
DR Pfam; PF00082; Peptidase_S8; 2.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 2.
DR PROSITE; PS51892; SUBTILASE; 2.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 2.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000075243};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 6..50
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 71..513
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 570..665
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT DOMAIN 692..770
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 791..1242
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 1298..1393
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 79
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 140
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 462
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 799
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 860
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 1191
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KYP40420.1"
SQ SEQUENCE 1399 AA; 150883 MW; 1BFC929EBE3BE521 CRC64;
SDIEPAEAIL HSYKKSFNGF VVKLTEDEAE RMAEMEDVVS VFPNKKNRLH TTKSWDFIGV
SPQVKRSNIE SDIIVGVIDS GVWPESKSFS DQGFGPPPKK WKGSCHNFTC NNKIIGAKYI
NIEGYYSKSD IISPIDTGGH GTHTASMVAG NWVNSASVLG FGSGTARGGV PSARIAVYKA
IGCGSEADTL AAFDEAIADG VDIISLSLGP FEPKHYFEDA IDIGSFHAMK RGILTSHAAG
NDGPRPSTIT NYSPWLLSVA ATTIDRKFML GTAAKPLSGT SINTFDLKNK MFPLIFSGNA
PNTADGYNSS ISRLCLDNSL DKHLVKGKIV LCDGFDSSKV GGLSGAVGML VGSPISKDSP
FTLALPAALL SQRNILSVFS YMTSTSNSTA TIFRSVEVND TAAPYVASFS ARGPNPFTPN
TLKPDLAAPG VNILAAWTPL NPISHFKGDK RPAHYNLAFG TSMACPHASA AAAYVKSFHP
NWSPAMIKSA LMTTATPMSP TPNPDVEFAY GAGQINPVKA ANPGLVYDIS EADYVKFLCG
EGLTNEQLRK ITRDHSSCSK HSKKEAVYEF NLPSFALHVN VSEYFSHVFN RTVTNVGLAT
SSYKAKVVSP SLLDIQVEPN VLSFTSIGQK KKFSVIIEGS INVEILSASI VWDDGTFQVR
TTIVVQILVA SRVKYYSSTT SYKHADKLKR MTYIVYMGDH PKGMDSTSIP SLHTAMAQKV
LGSDFKPEAL LHSYKNFNAF VMKLTEEEAE RTAEMENVIS VFPNSKKSLH TTRSWNFIDF
PQNVKRETRE SDIIVGVLDS GIWPESESFS GKGFGPPPSR WKGSCHNFTC NNKIIGAKYF
NLEHEFAKED IISPRDAEGH GSHCASTVAG NSVNSVSLFG LASGAARGGV PSARIAVYKV
CWKEHCHDDD ILAAFDEAIS DGVDIISISI GPRIVHYFPY FQDPTHIGSF HAMKRGILTS
NSGGNEGPSF SSMSNLAPWL LSVAASSFDR KIVTKVQLGN GAVYEGVSIN TFNLKKKLYP
LIYGGDIPNI AGGHNSSTSR YCIRNSLDKD SVKGKIVLCE ITHGTDIDSL SGIGAVGVIL
GSNSPQDSAS AFVLPAAILS PWNQRLIHSY ITSTRNATAT IFKSEEINDG LIPFVASFSS
RGPNPITPNT LKPDIAAPGV EVIAAWSPVS PISDVKGDKR KVQYNVISGT SMACPHASAA
AAYIKSFHPN WSPAMIKSAL MTTATPMSHV LNPEAEFAYG AGLINPVKAA NPGLVYDISE
ADYIKFLCGE GYTDEMLRNL TKDHSSCKVQ ASKRAVYELN LPSFALFTNH STFSRAYFRT
VTNVGSATAT YKARVIASPL LQIQVKPSTL SFTSIGQKKS FSLIIEGITN LDIISASLIW
DDGSHQVRSP IVVYGRMGM
//
