ID   A0A151WSX9_9HYME        Unreviewed;       824 AA.
AC   A0A151WSX9;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   22-FEB-2023, entry version 20.
DE   RecName: Full=guanylate cyclase {ECO:0000256|ARBA:ARBA00012202};
DE            EC=4.6.1.2 {ECO:0000256|ARBA:ARBA00012202};
GN   ORFNames=ALC60_10073 {ECO:0000313|EMBL:KYQ50933.1};
OS   Trachymyrmex zeteki.
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC   Formicidae; Myrmicinae; Trachymyrmex.
OX   NCBI_TaxID=64791 {ECO:0000313|EMBL:KYQ50933.1, ECO:0000313|Proteomes:UP000075809};
RN   [1] {ECO:0000313|EMBL:KYQ50933.1, ECO:0000313|Proteomes:UP000075809}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tzet28-1 {ECO:0000313|EMBL:KYQ50933.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:KYQ50933.1};
RA   Nygaard S., Hu H., Boomsma J., Zhang G.;
RT   "Trachymyrmex zeteki WGS genome.";
RL   Submitted (SEP-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the adenylyl cyclase class-4/guanylyl cyclase
CC       family. {ECO:0000256|RuleBase:RU000405}.
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DR   EMBL; KQ982769; KYQ50933.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A151WSX9; -.
DR   STRING; 64791.A0A151WSX9; -.
DR   Proteomes; UP000075809; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004383; F:guanylate cyclase activity; IEA:UniProtKB-EC.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 6.10.250.780; -; 1.
DR   Gene3D; 3.90.1520.10; H-NOX domain; 1.
DR   Gene3D; 3.30.450.260; Haem NO binding associated domain; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR018297; A/G_cyclase_CS.
DR   InterPro; IPR038158; H-NOX_domain_sf.
DR   InterPro; IPR011644; Heme_NO-bd.
DR   InterPro; IPR011645; HNOB_dom_associated.
DR   InterPro; IPR042463; HNOB_dom_associated_sf.
DR   InterPro; IPR024096; NO_sig/Golgi_transp_ligand-bd.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   PANTHER; PTHR45655; GUANYLATE CYCLASE SOLUBLE SUBUNIT BETA-2; 1.
DR   PANTHER; PTHR45655:SF10; SOLUBLE GUANYLATE CYCLASE 88E; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   Pfam; PF07700; HNOB; 1.
DR   Pfam; PF07701; HNOBA; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF111126; Ligand-binding domain in the NO signalling and Golgi transport; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   PROSITE; PS00452; GUANYLATE_CYCLASE_1; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|RuleBase:RU000405};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00023134};
KW   Reference proteome {ECO:0000313|Proteomes:UP000075809}.
FT   DOMAIN          424..552
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   COILED          367..394
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   824 AA;  93974 MW;  129C2FB56F0A9D31 CRC64;
     MYGLILENLA EYIRQVYGED RWEEIRRQAS VDQPSFSVHQ VYSENLIPRL AKKAIQVLGV
     TEKEFFDQMG VHFVGFVGQY GYDRVLSVLG RHVRDFLNGL DNLHEYLKFS YPRMRAPSFI
     CENETRQGLT LHYRSKRRGF VYYTMGQIRE VARHFYHKEL QIELVREEVL FDTVHVTFQL
     IFDNRAFTLA SLAMTREEKH LPIGACVLFE IFPFCIVFGS DMIVRSIGNS LMVILPDLVG
     KKITYFFDLV RPLIAFKFQS ILNRTNNIFE LVTVEPVLTE RLNDRHRNEI LLSDELETVE
     DKTLRLKGQM IYMDNWKMMM YLGTPVMPDL NALIATGLYI NDLSMHDFSR DLMLAGTQQS
     VELKLALDQE QLKSKKLEES MRKLDEEMKR TDELLYQMIP KQVADRLRNG ESPIDTCEMF
     DSVSILFSDV VTFTEICSRI SPMEVVSMLN AMYSLFDTLT ERNRVYKVET IGDAYMVVSG
     APVKENDHAD RVCDMALDMV EAITDLKDRS TGNHLQIRVG IHSGAVVAGI VGLKMPRYCL
     FGDSVNTAAR MEATSQAMQI HISQSTQELL SPSYKVKERE EIEVKGKGTM KTYWLEKRER
     RSVTTKGITI QEPHQWHTKS FEKRVPSVGA IGLISTGMFD KSTSGDALSR RRGSAFLSEE
     RRIYSPITFQ DVALRSIANS PTKNVEVREC RSNSMGAVGT SSASDMFSSL LNDTEEHFRQ
     HRNNLSVRVG ENQSASVHVK PEVKINVTSS LSSQSSEEES NLDFTLQTQK DNANARVDND
     NECAAISSDL NNSQLLTQQD QCCPGFTISK SSKMRHQGNS CIIV
//