ID   A0A158M9G2_9BORD        Unreviewed;       487 AA.
AC   A0A158M9G2;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   RecName: Full=RNA polymerase sigma-54 factor {ECO:0000256|PIRNR:PIRNR000774};
GN   Name=rpoN {ECO:0000313|EMBL:KAK99619.1};
GN   ORFNames=L497_3178 {ECO:0000313|EMBL:KAK99619.1};
OS   Bordetella holmesii CDC-H585-BH.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=1331206 {ECO:0000313|EMBL:KAK99619.1, ECO:0000313|Proteomes:UP000026682};
RN   [1] {ECO:0000313|EMBL:KAK99619.1, ECO:0000313|Proteomes:UP000026682}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CDC-H585-BH {ECO:0000313|EMBL:KAK99619.1,
RC   ECO:0000313|Proteomes:UP000026682};
RA   Harvill E., Goodfield L.L., Ivanov Y., Meyer J.A., Newth C., Cassiday P.,
RA   Tondella M.L., Liao P., Zimmerman J., Meert K., Wessel D., Berger J.,
RA   Dean J.M., Holubkov R., Burr J., Liu T., Brinkac L.M., Sanka R., Kim M.,
RA   Losada L.;
RT   "Genome sequence of Bordetella holmseii.";
RL   Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Sigma factors are initiation factors that promote the
CC       attachment of RNA polymerase to specific initiation sites and are then
CC       released. {ECO:0000256|PIRNR:PIRNR000774}.
CC   -!- SIMILARITY: Belongs to the sigma-54 factor family.
CC       {ECO:0000256|ARBA:ARBA00008798, ECO:0000256|PIRNR:PIRNR000774}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KAK99619.1}.
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DR   EMBL; JFZZ01000009; KAK99619.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A158M9G2; -.
DR   STRING; 35814.BBB42_00610; -.
DR   PATRIC; fig|1331206.3.peg.197; -.
DR   Proteomes; UP000026682; Unassembled WGS sequence.
DR   GO; GO:0000428; C:DNA-directed RNA polymerase complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0001216; F:DNA-binding transcription activator activity; IEA:InterPro.
DR   GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016987; F:sigma factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0006352; P:DNA-templated transcription initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 1.10.10.1330; RNA polymerase sigma-54 factor, core-binding domain; 1.
DR   InterPro; IPR000394; RNA_pol_sigma_54.
DR   InterPro; IPR007046; RNA_pol_sigma_54_core-bd.
DR   InterPro; IPR007634; RNA_pol_sigma_54_DNA-bd.
DR   InterPro; IPR038709; RpoN_core-bd_sf.
DR   NCBIfam; TIGR02395; rpoN_sigma; 1.
DR   PANTHER; PTHR32248; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR   PANTHER; PTHR32248:SF4; RNA POLYMERASE SIGMA-54 FACTOR; 1.
DR   Pfam; PF00309; Sigma54_AID; 1.
DR   Pfam; PF04963; Sigma54_CBD; 1.
DR   Pfam; PF04552; Sigma54_DBD; 1.
DR   PIRSF; PIRSF000774; RpoN; 1.
DR   PRINTS; PR00045; SIGMA54FCT.
DR   PROSITE; PS00717; SIGMA54_1; 1.
DR   PROSITE; PS00718; SIGMA54_2; 1.
DR   PROSITE; PS50044; SIGMA54_3; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PIRNR:PIRNR000774};
KW   DNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022478,
KW   ECO:0000256|PIRNR:PIRNR000774};
KW   Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695,
KW   ECO:0000256|PIRNR:PIRNR000774};
KW   Sigma factor {ECO:0000256|ARBA:ARBA00023082,
KW   ECO:0000256|PIRNR:PIRNR000774};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163,
KW   ECO:0000256|PIRNR:PIRNR000774};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW   ECO:0000256|PIRNR:PIRNR000774};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR000774}.
FT   DOMAIN          115..311
FT                   /note="RNA polymerase sigma factor 54 core-binding"
FT                   /evidence="ECO:0000259|Pfam:PF04963"
FT   DOMAIN          326..481
FT                   /note="RNA polymerase sigma factor 54 DNA-binding"
FT                   /evidence="ECO:0000259|Pfam:PF04552"
FT   REGION          60..117
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        64..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   487 AA;  53488 MW;  FC75B8EA908ED522 CRC64;
     MRSGEVGFIM QNIVPMSRPA LELRPGQHLT LTPQLQQSIR LLQLSSLDLE AEISQALAEN
     PLLERDETPA EQIDSDPQRE ASLDTADSVT DTEIRFDDMP GSGGVYPDED SDSPARSDTL
     REHLLQQLAL TRAGVRDAAL AALLIDELDD NGYLGSPLSE ILQWLPAELE VDEDELRAAL
     SLVQSFDPTG IGARDMAECL LLQLRHPDVA RLPEAASPAV LGCARELCGQ HLALLATGNP
     ARLREMLRVD EATLRAARAL IVRLEPRPGR AWTVPAAEYA VPDVLVRKTR QGWQAVLNSA
     VMPRLQVNGL YAQMLSNQRE AAYAGLNAQL QQARWMIRNV EQRFDTILRV AQAIVAHRAE
     FFTRGPAAMR PLILKDIAGE LGLHESTISR ATTQKYMLTP FGTMELKRFF GTGVAMDSGD
     SASATAVQEH IRQMVADENR AKPLSDSQIM ERLAGQGIVI ARRTVAKYRE ALRIAPAAVR
     KAQAAAR
//