ID A0A158NEB0_ATTCE Unreviewed; 564 AA.
AC A0A158NEB0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 30.
DE RecName: Full=Aldehyde dehydrogenase domain-containing protein {ECO:0000259|Pfam:PF00171};
GN Name=105618947 {ECO:0000313|EnsemblMetazoa:XP_012055868.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012055868.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012055868.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR EMBL; ADTU01013229; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01013230; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01013231; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01013232; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012055868.1; XM_012200478.1.
DR AlphaFoldDB; A0A158NEB0; -.
DR STRING; 12957.A0A158NEB0; -.
DR EnsemblMetazoa; XM_012200478.1; XP_012055868.1; LOC105618947.
DR GeneID; 105618947; -.
DR KEGG; acep:105618947; -.
DR eggNOG; KOG2456; Eukaryota.
DR InParanoid; A0A158NEB0; -.
DR OrthoDB; 606537at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR GO; GO:0006081; P:cellular aldehyde metabolic process; IEA:InterPro.
DR CDD; cd07132; ALDH_F3AB; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR012394; Aldehyde_DH_NAD(P).
DR PANTHER; PTHR43570; ALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43570:SF16; ALDEHYDE DEHYDROGENASE TYPE III, ISOFORM Q; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 535..556
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 69..490
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 273
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 564 AA; 63377 MW; 8DC2708783A50391 CRC64;
MINIIKLQLD SRTPHSGSSN MTETILDIPD ASEEMDASDI CHIDMQTAVL DVSESSQTND
KQIPINYADL VQQSRDTFNS GKTRPIEWRI KQLKQLILML TENASELTAA FTSDLHRCKF
ESFALEINYT IQEIKYMLMN IKEWAATEKP RKSLAHFFDV VEIRKDPYGV VLVMGAWNYP
LQLCILPMMG AIAAGNCVIV KPSEIAMATT KFLYDTVPKY LDTDSCRVIL GGISETTELL
KQRFDYIFYT GSSAVGKIIR KAANEFLTPV TLELGGKSPV YIDNTVDISM AAKRILWGKC
INVGQTCIAP DYMLCTPEIQ KKFIEEAKKI LHEWYGDNPR ESPDLARIIS DKHYQRLVNY
LNDKSKIAIG GDVNPAEKFI SPTVLVNIKP TDSIMQEEIF GPLLPIININ NAYEAINFIN
SRESPLVLYV FSTSKGVQDL IIDQVSSGAV CVNDTVLQYA VDTLPFGGVG YSGIGAYHGK
FTFDTFTHKK GCLIRNYNKI AEILAKSRFP PYSDANLKLL QLLVARRPSL PLLKYIPYIL
MFGLGMLATF GIKAIMKEYN YMEE
//
