ID A0A158NF67_ATTCE Unreviewed; 1350 AA.
AC A0A158NF67;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE RecName: Full=UDENN domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=105619261 {ECO:0000313|EnsemblMetazoa:XP_012056175.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012056175.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012056175.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
CC -!- SIMILARITY: Belongs to the RAB6IP1 family.
CC {ECO:0000256|ARBA:ARBA00006664}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
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DR EMBL; ADTU01013890; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01013891; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01013892; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012056175.1; XM_012200785.1.
DR STRING; 12957.A0A158NF67; -.
DR EnsemblMetazoa; XM_012200785.1; XP_012056175.1; LOC105619261.
DR GeneID; 105619261; -.
DR KEGG; acep:105619261; -.
DR eggNOG; KOG2080; Eukaryota.
DR InParanoid; A0A158NF67; -.
DR OrthoDB; 5398783at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR CDD; cd01757; PLAT_RAB6IP1; 1.
DR CDD; cd17677; RUN1_DENND5; 1.
DR CDD; cd17678; RUN2_DENND5; 1.
DR Gene3D; 1.20.58.900; -; 3.
DR Gene3D; 3.30.450.200; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR047278; DEN5A/B.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR InterPro; IPR047277; PLAT_RAB6IP1.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR46070; PINSTRIPE, ISOFORM A; 1.
DR PANTHER; PTHR46070:SF1; PINSTRIPE, ISOFORM A; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF01477; PLAT; 1.
DR Pfam; PF02759; RUN; 2.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00593; RUN; 2.
DR SMART; SM00800; uDENN; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR SUPFAM; SSF140741; RUN domain-like; 2.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS50095; PLAT; 1.
DR PROSITE; PS50826; RUN; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 36..591
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT DOMAIN 768..1003
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 1007..1115
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DOMAIN 1180..1343
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT REGION 140..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..714
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..909
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 699..714
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1350 AA; 154192 MW; 191D5FA8B3A1CDAA CRC64;
MNGSLGITRG PEQHPQRFAD YFVICGLDKD SGLEPDKYFG DSLQCTPLDR AYKSKVLGHY
PDSVPWNPFD EHAVCMLCLP SGLRFRTQKH SVEPTFHSFV LTKEDGHRTY GFSLVFYEEC
RNRKICSAMQ TLQAMHITEL SSGQNGTPPT ARKGQDGHNT RSLPRHFKLS AHSPGAALGY
YDSTKDKLLV TKSISLLCQQ PYLHATKTFL TNLYKCVPRH PGPGLSLESY VYNLLYNVPV
PLPGKSLKFF VPNDEPAKSP LELVIHQPSP SLELPMLDYP LKDVFTWLGA DCLIQLFTCV
LLENQVLLRS ADFHKLMVVS ECITALLFPF SWQHVYVPIL PASLHHFLDA PVPFIMGLHA
HNEGGVLKIA SEANLCYVDI DKQSSQFPEE LPVFPHKMQF INEIRALLNK YKIPHSGKTD
NMVINYYNGD IMTSSLTLPG SGFHLPRRKH SLHDVLDWDR PELGPQSDNL QRTVDIVKRV
NMDDIDPIED TTEKILMPQE EYQETLIFNN AIREIFLNRF VQMFSSYEHF VIQPSQDKDE
WINNRDSMHV FDKATFLSDQ PTQHLPFLSR FLETQMFASL VDSKVMSTWS ELDCNIKVFD
QRISALKKKV GESIIRSMRY ESCTSIADTQ HILDQRLINT DFETNPPAEI LPHRAAYFRS
FPLLDNVALN KEPAQSILRS RRGQTQWKYK MKSMDTNGKP AIPQESQSPR PQTKLSADMS
PALIAQANWT FVEKLLKDCK SKTKRMLVEK MGSEAVALGH GGESLSDVEE NTLVASLCDL
LERVWSHGLQ NKQGKSALWS HLTMYQESEE CNDATKSIDS NFLSPGKTCM VXYLXLDECL
VKKNIVFMCI LFASLGLXLE KCLYLKYFTL XLKLHIDLSN LQLETDVSPT RSTDKHKSSS
ERKTIGPEHL RPLPDSLIFD IRNIQAMTDI KTHIGYARAW VRLALEKKLL SRHLKTLLSD
NALLRTQYKR SAFLRCEEEK EQFLYHLLTL NAVDYFCFTN NYPTTKLPYR VVIFPSRKAS
AATTSANSWI AISGTLCETN PVPIPKGALE FVFHHKNLGV LSTLRIGHDN TGLSPKWMVE
HVVVRNEVTG HTFKFPCGRW LGRGIDDGST ERLLVGALVP RSIDSEELVE SCSTPPRCRS
PSIPRRPIFS QVELQHMLGE AVNAIVKYHY RRECQDGSLT ALLCGEGGLV PSLEQIFLFG
FKNQRIFGRN FYVWDYLLRI KENFEISLLE EMDEYSQRLN RDRRVYTESS QRFTILRCYC
HLIDQINIFS QTLGKDGKFQ LFICLAAREQ LLYPMLRPMS DARSTMDMYE ENSFLRNPTL
LTFLIHILEP LSEFHIVLEK SLTHGISSIC
//
