ID A0A158NGX7_ATTCE Unreviewed; 1662 AA.
AC A0A158NGX7;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=PH domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=105619877 {ECO:0000313|EnsemblMetazoa:XP_012056785.1};
OS Atta cephalotes (Leafcutter ant).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Formicoidea;
OC Formicidae; Myrmicinae; Atta.
OX NCBI_TaxID=12957 {ECO:0000313|EnsemblMetazoa:XP_012056785.1, ECO:0000313|Proteomes:UP000005205};
RN [1] {ECO:0000313|Proteomes:UP000005205}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21347285; DOI=10.1371/journal.pgen.1002007;
RA Suen G., Teiling C., Li L., Holt C., Abouheif E., Bornberg-Bauer E.,
RA Bouffard P., Caldera E.J., Cash E., Cavanaugh A., Denas O., Elhaik E.,
RA Fave M.J., Gadau J., Gibson J.D., Graur D., Grubbs K.J., Hagen D.E.,
RA Harkins T.T., Helmkampf M., Hu H., Johnson B.R., Kim J., Marsh S.E.,
RA Moeller J.A., Munoz-Torres M.C., Murphy M.C., Naughton M.C., Nigam S.,
RA Overson R., Rajakumar R., Reese J.T., Scott J.J., Smith C.R., Tao S.,
RA Tsutsui N.D., Viljakainen L., Wissler L., Yandell M.D., Zimmer F.,
RA Taylor J., Slater S.C., Clifton S.W., Warren W.C., Elsik C.G., Smith C.D.,
RA Weinstock G.M., Gerardo N.M., Currie C.R.;
RT "The genome sequence of the leaf-cutter ant Atta cephalotes reveals
RT insights into its obligate symbiotic lifestyle.";
RL PLoS Genet. 7:e1002007-e1002007(2011).
RN [2] {ECO:0000313|EnsemblMetazoa:XP_012056785.1}
RP IDENTIFICATION.
RG EnsemblMetazoa;
RL Submitted (APR-2016) to UniProtKB.
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DR EMBL; ADTU01015316; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01015317; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01015318; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; ADTU01015319; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_012056785.1; XM_012201395.1.
DR STRING; 12957.A0A158NGX7; -.
DR EnsemblMetazoa; XM_012201395.1; XP_012056785.1; LOC105619877.
DR GeneID; 105619877; -.
DR KEGG; acep:105619877; -.
DR eggNOG; KOG0248; Eukaryota.
DR InParanoid; A0A158NGX7; -.
DR OrthoDB; 4538469at2759; -.
DR Proteomes; UP000005205; Unassembled WGS sequence.
DR GO; GO:0071944; C:cell periphery; IEA:UniProt.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0009887; P:animal organ morphogenesis; IEA:UniProt.
DR GO; GO:0030182; P:neuron differentiation; IEA:UniProt.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd17094; FERM_F1_Max1_like; 1.
DR CDD; cd00821; PH; 1.
DR CDD; cd13282; PH1_PLEKHH1_PLEKHH2; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 1.25.40.530; MyTH4 domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 3.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR000857; MyTH4_dom.
DR InterPro; IPR038185; MyTH4_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR22903:SF8; MAX-1A; 1.
DR PANTHER; PTHR22903; PLEKHH PROTEIN; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF00784; MyTH4; 1.
DR Pfam; PF00169; PH; 2.
DR SMART; SM00295; B41; 1.
DR SMART; SM00139; MyTH4; 1.
DR SMART; SM00233; PH; 2.
DR SUPFAM; SSF50729; PH domain-like; 2.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS50057; FERM_3; 1.
DR PROSITE; PS51016; MYTH4; 1.
DR PROSITE; PS50003; PH_DOMAIN; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000005205};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 816..910
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 924..1029
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT DOMAIN 1064..1282
FT /note="MyTH4"
FT /evidence="ECO:0000259|PROSITE:PS51016"
FT DOMAIN 1293..1615
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 24..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 603..625
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 637..677
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 699..796
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1169..1196
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1636..1662
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 333..374
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 442..476
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 65..91
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..144
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..677
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 720..773
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1636..1655
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1662 AA; 183481 MW; 0878784435354560 CRC64;
MDEIRGSSSG RRLSQILDPI TRLASDFGSN SAPCSPRLGA RVQDPSSGPA AAGQSGPIGA
AGPATAGVSS SSRAGPSGAG TGSSNSGPDS PRLWPRQFRQ APTPPPRPRH AGAAATTAIS
TASTSTSVST NVNNNNNNNN AGSGVDSGAP LSVIHTRDSP YVNVSNLFFH KDKSFAENAR
SAGYIELREK PKCSPYDFTS ESSGHVEYAD KRTFVTPVQS DLAYDVGKEP GSPLCRGRSN
YDPGPSSGRS HFDRAFSFSG RQPSELPASR IYEAGRLFVD PRATGGNVDL KREKLDVRPT
YSTSKSFDGY TTVEELNWQE RCLELQLELH RSRSQATRVR DMLREKLSEL EQRVLEAEGR
ADEAEDKVRM MEERLVKGEY CLSTSGVGSP PHSLPSTSGT QNDKIEEVHC ACISKLETQV
EEQRQLRLHD ARQVEAKAAR IKEWVTNKLR ELEQQNQHLR EQNNKCNQQL ELLRNHITNI
GLKPPAPTRA SLSLEVDPTL RIDRRRSESL EGTPQTAPEC VQNIVTEPQT STKHRRHLSA
CGNIQRGIAT TNMDSSLLSE ELAAAVENLV MLPNMSGVSE ASRDSGSSEA VHDYAEIYTP
SREGMNWLQG GGQGPRPPTP PLHRFPSWEA KIYQVADGGL GIGPPTNEES APSTMTTTTS
SSKHSQATGH NLTAHNSQGY CDISVPVYAT VKGRASQIRS MPFGDSSDDS SDGEEHPNQT
ETNTRITNSS SDNTDSSLGS GSSPSKSIKT TSSLSPAKRS SSGSPSKSVK RDTSLESGLS
EDYAIPPDAL SSTSLESSMP SLLMRVSGES PKRQESLEKT GHLAKLGGKL KTWRKRWFVL
KNGVLTYWKS QNDVNRKPQG QIILDEVCRI NRAEGAATFE IATGKKTYYL TADCIATMED
WIRVLQNVQR RNATKLLLSR EDNKPTIQGW LTKVKNGHAK KCWCVLIGKM FLYFKCPSDT
NPIGQINMRD ARVEEVEHVS DSDSEERDAE CPHERTIGIF PTHQGPTYLL MPHKQDKDNW
LYHLTVVSGG GPSAGTQYEQ LVQRLMETDG DPSCVLWRHP LLLHTKESIT SPLTSLTSET
LQTEAIKLFK ACQLFMSVAV EQAGIDYHVV LAQNALQQCL DQPELQSEFI CALVKQTSRH
TQHRLGVQQL LLCATQSLFT CDTQSPAANG SGENADAQST ASTSHSPPLT QGHSTSTILD
CKTNPAQYVL IQGWQLLALA VSLFLPKNNR LLWYLKLHLQ RNADSKTECG KYAAYCERAL
ERTLQNGSRE VKPSRMEVLS ILMKNPYHHS LPHAIPVHFL NGTYQVVSFD GSTTIEEFLN
TLNQEIGCRD VHQSGFTLFS DDPIEKDLEH FIDPEAKLCD IISKWETALR EKGSGKFENT
RVIQLTYKSR CYWRQAAKME TDKERLLLCY QVNQQVVQGK FPLNRELAFE LASLMAQIDF
GEYNNDKARG SGPGSNPHHL VLQALDKFYP LRYRANITAD QLRELQEKLQ EKWIALKGRS
VLDCVRIYLT CTRKWPFFGA TLYQAKLKQG DSVTVWIAVS EDSVTLLELQ TMAVMCRYNY
ANIVTFGGCL DDFMLVACPD EGAAEQKLLF ALSKPKILEI TLLIADYMNA LGHALPGTPQ
MNTLTRNGSH RSIKSTLRPA TGSSCLPTQP DILKSTPDHQ RP
//
